3 hasil untuk "Adrian Pirog"
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Artikel Jurnal
Burst of aneuploidy: a cost of adaptation driven by breakdown of cell cycle control
Abstract Complex genome rearrangements are intriguing because it remains unclear whether they occurred gradually or suddenly, and what promoted or impeded their development. We started by asking whether double loss of heterozygosity (dLOH) involving two different chromosomes is simply the result of…
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Artikel Jurnal
Extreme positive epistasis for fitness in monosomic yeast strains
The loss of a single chromosome in a diploid organism halves the dosage of many genes and is usually accompanied by a substantial decrease in fitness. We asked whether this decrease simply reflects the joint damage caused by individual gene dosage deficiencies. We measured the fitness effects of…
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Artikel Jurnal Teks lengkap
A Systematic Review on Quiescent State Research Approaches in S. cerevisiae
Quiescence, the temporary and reversible arrest of cell growth, is a fundamental biological process. However, the lack of standardization in terms of reporting the experimental details of quiescent cells and populations can cause confusion and hinder knowledge transfer. We employ the systematic…