10 hasil untuk "Aklima"

Region-specific variation and determinants of caesarean delivery among ever-married women in Bangladesh

Gobinda Karmakar; Md. Tariqujjaman; Aklima Alam dkk.

PLOS One, Vol. 20 No. 9 · 2025 · Inggris · PLOS Scopus

Background: The extensive use of caesarean delivery has adverse consequences for both maternal and neonatal health. This study aims is to investigate regional variation and identify region-specific determinants of caesarean deliveries among ever-married women in Bangladesh. Methods: A total of…

Oral immunization with a probiotic cholera vaccine induces broad protective immunity against Vibrio cholerae colonization and disease in mice

Brandon Sit; Ting Zhang; Bolutife Fakoya dkk.

PLOS Neglected Tropical Diseases, Vol. 13 No. 5 · 2019 · Inggris · PLOS Scopus

Oral cholera vaccines (OCVs) are being increasingly employed, but current killed formulations generally require multiple doses and lack efficacy in young children. We recently developed a new live-attenuated OCV candidate (HaitiV) derived from a Vibrio cholerae strain isolated during the 2010 Haiti…

Designing of a multiepitope-based vaccine against echinococcosis utilizing the potent Ag5 antigen: Immunoinformatics and simulation approaches

Rehana Parvin; Md. Habib Ullah Masum; Homaira Pervin Heema dkk.

PLOS ONE, Vol. 20 No. 2 · 2025 · Inggris · PLOS Scopus

Echinococcosis is a significant parasitic zoonotic disease with severe implications for human and animal health. To date, there has been no effective vaccine candidate available for echinococcosis. Therefore, we employed computational approaches to develop a multiepitope-based vaccine using the…

Dysmagnesemia in critically ill diarrheal patients in Bangladesh

Aklima Alam; Gazi Md. Salahuddin Mamun; Monira Sarmin dkk.

PLOS One, Vol. 20 No. 5 · 2025 · Inggris · PLOS Scopus

Background: Despite having a pivotal role in numerous physiologic functions, magnesium disorders are rarely considered in clinical practice. This study aimed to explore the burden, predictors, and outcomes associated with magnesium imbalances among critically ill patients admitted to critical care…

Prevalence and predictors of magnesium imbalance among critically ill diarrheal children and their outcome in a developing country

Gazi Md. Salahuddin Mamun; Monira Sarmin; Aklima Alam dkk.

PLOS ONE, Vol. 18 No. 12 · 2023 · Inggris · PLOS Scopus

Despite having essential roles in maintaining human body physiology, magnesium has gained little attention. We sought to evaluate the prevalence and predictors of magnesium imbalance in diarrheal children admitted to an intensive care unit. This retrospective data analysis was conducted among…

Personal and perceived stigma towards mental disorders among attendants of patients with mental illness in selected health facilities of Bangladesh

Shagoofa Rakhshanda; Labida Islam; Koustuv Dalal dkk.

PLOS One, Vol. 20 No. 10 · 2025 · Inggris · PLOS Scopus

The objective of this study was to explore the stigma among attendants (close relatives or other caregivers) who brought patients with mental illness to the selected mental health facilities in Bangladesh. This mixed-method study was part of a nationwide survey where respondents were conveniently…

An assessment of potential biomarkers of environment enteropathy and its association with age and microbial infections among children in Bangladesh

Muhammad Ikhtear Uddin; Motaher Hossain; Shahidul Islam dkk.

PLOS ONE, Vol. 16 No. 4 · 2021 · Inggris · PLOS Scopus

Interventional studies targeting environment enteropathy (EE) are impeded by the lack of appropriate, validated, non-invasive biomarkers of EE. Thus, we aimed to validate the association of potential biomarkers for EE with enteric infections and nutritional status in a longitudinal birth cohort…

Induction of systemic, mucosal and memory antibody responses targeting Vibrio cholerae O1 O-specific polysaccharide (OSP) in adults following oral vaccination with an oral killed whole cell cholera vaccine in Bangladesh

Aklima Akter; Pinki Dash; Amena Aktar dkk.

PLOS Neglected Tropical Diseases, Vol. 13 No. 8 · 2019 · Inggris · PLOS Scopus

Background: Oral cholera vaccine (OCV) containing killed Vibrio cholerae O1 and O139 organisms (Bivalent-OCV; Biv-OCV) are playing a central role in global cholera control strategies. OCV is currently administered in a 2-dose regimen (day 0 and 14). There is a growing body of evidence that immune…

Plasma and memory B cell responses targeting O-specific polysaccharide (OSP) are associated with protection against Vibrio cholerae O1 infection among household contacts of cholera patients in Bangladesh

Amena Aktar; M. Arifur Rahman; Sadia Afrin dkk.

PLOS Neglected Tropical Diseases, Vol. 12 No. 4 · 2018 · Inggris · PLOS Scopus

Background: The mediators of protection against cholera, a severe dehydrating illness of humans caused by Vibrio cholerae, are unknown. We have previously shown that plasma IgA as well as memory B IgG cells targeting lipopolysaccharide (LPS) of Vibrio cholerae O1 correlate with protection against…

Correction: Plasma and memory B cell responses targeting O-specific polysaccharide (OSP) are associated with protection against Vibrio cholerae O1 infection among household contacts of cholera patients in Bangladesh

Amena Aktar; M. Arifur Rahman; Sadia Afrin dkk.

PLOS Neglected Tropical Diseases, Vol. 15 No. 7 · 2021 · Inggris · PLOS Scopus