19 results for "Burhan Engin"

Safety of Biologic Agents in the Treatment of Psoriasis Vulgaris: An Integrated Review of Clinical Trials and Real-World Evidence

Burhan Engin; Emre Bayindir

Selçuk Tıp Dergisi, Vol. 42 No. 1 · 2026 · English · DOAJ

Psoriasis vulgaris is a chronic, immune-mediated inflammatory disease in which dysregulation of the TNF-α and IL-23/Th17 axes drives keratinocyte hyperproliferation and systemic comorbidities. Targeted biologic drugs-TNF-α inhibitors, the IL-12/23 p40 inhibitor ustekinumab, IL-23 p19 inhibitors…

A Case of Cutaneous Leishmaniasis Caused by Leishmania infantum

Serhat Sirekbasan; Erdal Polat; Zekayi Kutlubay et al.

Türkiye Parazitoloji Dergisi, Vol. 43 No. 1 · 2019 · Turkish · DOAJ Scopus

Leishmania is a disease that is transmitted via Phlebotomine sand flies. Two clinical forms of leishmaniasis are observed in humans: Visceral and cutaneous leishamniasis. The latter is very widespread in our country and may resolve by itself with scar formation. Whereas visceral leishmaniasis can…

Predictors of PASI90 response in patients with psoriasis treated with ınterleukin ınhibitors: observational cohort study

Burhan Engin; Yusuf Demir; Sera Nur Yucesoy et al.

Anais Brasileiros de Dermatologia, Vol. 100 No. 4 · 2025 · Portuguese · DOAJ Scopus

Abstract Background: Psoriasis is a chronic multisystem disorder, and the inhibition of different cytokine pathways has been associated with different treatment responses. Objective: To demonstrate independent predictors of PASI90 response in patients with psoriasis under biologic therapy and…

Evaluation of the level of serum Interleukins (IL-2, IL-4, IL-15 andIL-17) and its relationship with disease severity in patients with alopecia areata,

Özge Aşkın; Sera Nur Yücesoy; Erkam Coşkun et al.

Anais Brasileiros de Dermatologia, Vol. 96 No. 5 · 2021 · Portuguese · DOAJ Scopus

Abstract Background: Alopecia areata (AA) is a hair disease that causes hair loss without scarring. The etiopathogenesis of AA has not been fully understood yet. Objective: To determine serum interleukin levels (IL-2, IL-4, IL-15, and IL-17) in patients diagnosed with alopecia areata and to…

The use of an urticaria control test for the evaluation of omalizumab treatment response in patients diagnosed with chronic urticaria

Burhan Engin; Sera Nur Yücesoy; Özge Aşkın et al.

Turkderm Turkish Archives of Dermatology and Venereology, Vol. 54 No. 4 · 2020 · Turkish · DOAJ Scopus

Background and Design: Urticaria is a very common skin disease which is characterized by itchy, erythematous and edematous plaques. Angioedema can also be seen in half of the cases in addition to skin findings. In most cases of chronic urticaria, the underlying factor is not known. Omalizumab, a…

Comparison of Clinicopathological Findings of Spitz Nevus in Pediatric and Adult Patients

Tuğba Kevser Uzunçakmak; Sera Nur Yücesoy; Ayşe Mine Önenerk et al.

Turkish Archives of Pediatrics, Vol. 59 No. 1 · 2024 · English · DOAJ Scopus

Objective: The aim of this study is to evaluate the demographic characteristics of patients diagnosed with Spitz nevus and to investigate potential distinctions in clinicopathological findings of Spitz nevi in relation to age and location of the lesion. Materials and Methods: Clinical and…

Basal Cell Carcinoma

Yalçın Tüzün; Zekayi Kutlubay; Burhan Engin et al.

Skin Cancer Overview · 2011 · English · IntechOpen

Current Management of Malignant Melanoma: State of the Art

Zekayi Kutlubay; Burhan Engin; Server Serdaroğlu et al.

Highlights in Skin Cancer · 2013 · English · IntechOpen

Association Between Androgenetic Alopecia Severity and Sexual Dysfunction in Male and Female Patients Attending a Dermatology Clinic: An Exploratory Cross-Sectional Study

Defne Özkoca; Ali Emre Buğday; Mahmut Gazi Ergün et al.

European Medical Journal (2026) · 2026 · English · DOAJ

Background and objectives: Androgenetic alopecia (AGA) negatively impacts body image and psychosocial wellbeing, potentially contributing to sexual dysfunction. Yet, the direct relationship between AGA severity and sexual function remains underexplored. This exploratory study aimed to evaluate the…

Mucosal Lichen Planus: A Clinical Study of 145 Patients

Özge Aşkın; Defne Özkoca; Tuğba Kevser Üstünbaş Uzunçakmak et al.

Cerrahpaşa Medical Journal, Vol. 45 No. 2 · 2021 · English · DOAJ

…Cite this article as: Aşkın Ö, Özkoca D, Uzunçakmak TKU, Kutlu Ö, Engin B, Kutlubay Z. Mucosal lichen planus: A clinical study of 145 patients. Cerrahpaşa Med J. 2021;45(2):124-128.

Predictors of early high-level response to bimekizumab in patients with moderate-to-severe plaque psoriasis: a real-world cohort study

Burhan Engin; Yusuf Demir; Gurbuz Yildirim et al.

Anais Brasileiros de Dermatologia, Vol. 101 No. 3 · 2026 · Portuguese · DOAJ Scopus

Comparison of Corneal Topographical and Biomechanical Properties in Cases with Atopic Dermatitis and Healthy Subjects

Yusuf Yıldırım; Necip Kara; Tolga Yılmaz et al.

Türk Oftalmoloji Dergisi, Vol. 43 No. 3 · 2013 · Turkish · DOAJ

Pur po se: To compare the topographic, biomechanical, and thickness properties of corneas of patients with atopic dermatitis (AD) and of healthy individuals. Ma te ri al and Met hod: In this prospective, cross-sectional, and comparative study, 28 healthy individuals (control group) and 28 patients…

A Phaeohyphomycosis Case: A Rare Entity

Zekayi Kutlubay; Murat Küçüktaş; Övgü Aydin et al.

Zdravniški Vestnik, Vol. 83 No. 11 · 2014 · Slovenian · DOAJ Scopus

Phaeohyphomycosis is the term used to describe infections with darkly pigmented moulds appearing as septate filaments in host tissues. The disease is a histopathological rather than a clinical entity. A 79-year-old patient presented with multiple ulcerated lesions and nodules on the face…

Omalizumab versus cyclosporin-A for the treatment of chronic spontaneous urticaria: can we define better-responding endotypes?

Emek Kocatürk; Emel Bülbül Başkan; Özlem Su Küçük et al.

Anais Brasileiros de Dermatologia, Vol. 97 No. 5 · 2022 · Portuguese · DOAJ Scopus

Abstract Background: Chronic Spontaneous Urticaria (CSU) is characterized by recurrent wheals and/or angioedema for longer than 6-weeks. Guidelines recommend Omalizumab (Oma) as first-line and Cyclosporine-A (Cs-A) as second-line treatment in antihistamine resistant CSU. This step-wise algorithm…

Demographical and Clinical Characteristics, Risk Factors, and Prognosis of Adult Patients with Herpes Zoster in Türkiye: A Retrospective, Multi-Center Study (VARICOMP-Adult Study)

Esin Senol; Alpay Azap; Selda Sayin Kutlu et al.

Infectious Disease Reports, Vol. 17 No. 3 · 2025 · English · DOAJ Scopus

Introduction: Over the past few decades, the rising incidence of herpes zoster (HZ) rates appears to have been a global phenomenon. In Türkiye, there is a lack of comprehensive studies addressing the HZ burden of disease, risk factors, and clinical characteristics. The aim of the VARICOMP-Adult…

Evaluation of the diabetogenic effect of methotrexate in psoriatic arthritis patients with metabolic syndrome: a pilot study

Tannaz Dehpouri; Ghasem Rahmatpour Rokni; Nematollah Ahangar Narenjbon et al.

Dermatology Reports, Vol. 11 No. 1 · 2019 · English · DOAJ Scopus

Methotrexate is a systemic immunosuppressant drug that is used for the treatment of psoriasis and psoriatic arthritis. Previous studies demonstrated a potential association between psoriasis and diabetes mellitus, obesity, atherosclerosis and hypertension. This study aimed at exploring the possible…

Disease burden, clinical management and unmet treatment need of patients with moderate to severe alopecia areata; consensus statements, insights, and practices from CERTAAE (Central/Eastern EU, Russia, Türkiye AA experts) Delphi panel

Lidia Rudnicka; Magdalena Trzeciak; Erkan Alpsoy et al.

Frontiers in Medicine, Vol. 11 · 2024 · English · DOAJ Scopus

ObjectivesThis study aims to update the understanding of Alopecia Areata (AA) in Poland, Czechia, Russia, and Türkiye, focusing on the disease burden, clinical management, and patient journey. It seeks to establish a consensus on optimal management strategies for AA in these regions.MethodsA…

Disease burden, clinical management and unmet treatment need of patients with moderate to severe atopic dermatitis; consensus statements, insights and practices from CERTADE (Central/Eastern EU, Russia, Turkiye AD Experts) Delphi panel

Magdalena Trzeciak; Lidia Rudnicka; Petr Arenberger et al.

Frontiers in Medicine, Vol. 11 · 2024 · English · DOAJ Scopus

BackgroundThere is limited insight into the current disease burden and everyday clinical management of moderate-to- severe AD in Poland, Czechia, Russia, and Turkiye. Therefore, this study aimed to get information-driven insights regarding the current disease burden and clinical management of…

A Multicenter Randomized Double-Blind Vehicle-Controlled Parallel Group Phase 2 Study Evaluating the Efficacy and Safety of GN-037 Cream in Patients with Mild-to-Moderate Plaque Psoriasis

Burhan Engin; Müge Güler Özden; Özge Sevil Karstarlı Bakay et al.

Dermatology and Therapy, Vol. 14 No. 12 · 2024 · English · DOAJ Scopus

Abstract Introduction Topical therapies are used in almost all patients with psoriasis. A novel fixed topical combination cream (GN-037) with a lower concentration (0.0356%) of clobetasol 17-propionate (CP) was developed together with urea, salicylic acid, and retinoic acid to provide a better…