6 results for "CM"

Acridine orange fluorescent microscopy is more sensitive than India ink light microscopy in the rapid detection of cryptococcosis among CrAg positive HIV patients

Richard Kwizera; Andrew Akampurira; Darlisha Williams et al.

PLOS ONE, Vol. 12 No. 7 · 2017 · English · PLOS Scopus

Background: India ink microscopy on cerebrospinal fluid is still utilized in resource limited settings for the diagnosis of cryptococcal meningitis despite its poor sensitivity. We hypothesized that staining fungal nucleic acids with fluorescent dyes instead of the capsule with India ink might…

Differential Programming of B Cells in AID Deficient Mice

Marc A. Hogenbirk; Marinus R. Heideman; Arno Velds et al.

PLoS ONE, Vol. 8 No. 7 · 2013 · English · PLOS Scopus

The Aicda locus encodes the activation induced cytidine deaminase (AID) and is highly expressed in germinal center (GC) B cells to initiate somatic hypermutation (SHM) and class switch recombination (CSR) of immunoglobulin (Ig) genes. Besides these Ig specific activities in B cells, AID has been…

The Value of a Checklist for Child Abuse in Out-of-Hours Primary Care: To Screen or Not to Screen

Maartje CM Schouten; Henk F. van Stel; Theo JM Verheij et al.

PLOS ONE, Vol. 12 No. 1 · 2017 · English · PLOS Scopus

Objectives: To assess the diagnostic value of the screening instrument SPUTOVAMO-R2 (checklist, 5 questions) for child abuse at Out-of-hours Primary Care locations (OPC), by comparing the test outcome with information from Child Protection Services (CPS). Secondary, to determine whether reducing…

The Influence of Differentially Expressed Tissue-Type Plasminogen Activator in Experimental Autoimmune Encephalomyelitis: Implications for Multiple Sclerosis

Lisa CM Dahl; Zeyad Nasa; JieYu Chung et al.

PLOS ONE, Vol. 11 No. 7 · 2016 · English · PLOS Scopus

Tissue type plasminogen activator (t-PA) has been implicated in the development of multiple sclerosis (MS) and in rodent models of experimental autoimmune encephalomyelitis (EAE). We show that levels of t-PA mRNA and activity are increased ~4 fold in the spinal cords of wild-type mice that are mice…

Proteomic analysis of plasma exosomes from Cystic Echinococcosis patients provides in vivo support for distinct immune response profiles in active vs inactive infection and suggests potential biomarkers

Federica Fratini; F. Tamarozzi; G. Macchia et al.

PLOS Neglected Tropical Diseases, Vol. 14 No. 10 · 2020 · English · PLOS Scopus

The reference diagnostic method of human abdominal Cystic Echinococcosis (CE) is imaging, particularly ultrasound, supported by serology when imaging is inconclusive. However, current diagnostic tools are neither optimal nor widely available. The availability of a test detecting circulating…

Correction: Temporal Patterns of Influenza A and B in Tropical and Temperate Countries: What Are the Lessons for Influenza Vaccination?

S Caini; W Andrade; S Badur et al.

PLOS ONE, Vol. 11 No. 5 · 2016 · English · PLOS Scopus