8 hasil untuk "David Musheyev"
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Artikel Jurnal
Endocrine therapy resistance: what we know and future directions
Endocrine resistance is a major hurdle in the treatment of estrogen receptor (ER)-positive breast cancer. When abnormally regulated, molecular signals responsible for cellular proliferation, as well as ER itself, allow for cellular evasion of ER-dependent treatments. Therefore, pharmacological…
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Artikel Jurnal
Assessment of Artificial Intelligence Chatbot Responses to Top Searched Queries About Cancer
Importance: Consumers are increasingly using artificial intelligence (AI) chatbots as a source of information. However, the quality of the cancer information generated by these chatbots has not yet been evaluated using validated instruments. Objective: To characterize the quality of information and…
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Artikel Jurnal Teks lengkap
Inhibition of ERK signaling for treatment of ERRα positive TNBC.
Breast cancer is the second leading cause of cancer-related deaths in women and triple-negative breast cancer (TNBC), in particular, is an aggressive and highly metastatic type of breast cancer that does not respond to established targeted therapies and is associated with poor prognosis and worse…
Juga tersedia di: PLOS
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Artikel Jurnal
Single-Cell Approach Reveals Intercellular Heterogeneity in Phage-Producing Capacities
ABSTRACT Bacteriophage burst size is the average number of phage virions released from infected bacterial cells, and its magnitude depends on the duration of an intracellular progeny accumulation phase. Burst size is often measured at the population level, not the single-cell level, and…
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Artikel Jurnal
Inequity of NIH cancer funding in the United States: an ecological study predicting funding based on disease burden from 2008 through 2023Research in context
Summary: Background: Disease burden has been used to predict National Institutes of Health (NIH) funding but included diseases with little underlying relationship. Here we focus on cancers to create a more appropriate model to allow for more targeted scrutinization of funding allocation. Methods…
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Artikel Jurnal
Pharmacovigilance of lower urinary tract adverse events among commonly prescribed medications: A FAERS database analysis
Background:: Lower urinary tract symptoms (LUTS) are a diverse group of urologic conditions characterized by dysfunction in storage, voiding, and post-micturition control. Previous studies estimate that medications account for 10% of LUTS in men. Pharmacovigilance studies, such as those using the…
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Artikel Jurnal
Social defeat stress induces depression-like behavior and alters spine morphology in the hippocampus of adolescent male C57BL/6 mice
Social stress, including bullying during adolescence, is a risk factor for common psychopathologies such as depression. To investigate the neural mechanisms associated with juvenile social stress-induced mood-related endophenotypes, we examined the behavioral, morphological, and biochemical effects…