14 hasil untuk "Devendra Kumar"
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Noise and neglect: Social-media signals expose attention gaps for dengue, chikungunya, lymphatic filariasis and kala-azar in India’s vector-borne NTDs
Background: Neglected tropical and vector-borne diseases, including dengue, chikungunya, lymphatic filariasis, and kala-azar, pose substantial public health burdens in India. Despite WHO recommendations for enhanced disease surveillance and targeted communication strategies, little is known about…
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Analytical solution of fuzzy heat problem in two-dimensional case under Caputo-type fractional derivative
This work aims to investigate the analytical solution of a two-dimensional fuzzy fractional-ordered heat equation that includes an external diffusion source factor. We develop the Sawi homotopy perturbation transform scheme (SHPTS) by merging the Sawi transform and the homotopy perturbation scheme…
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De novo genome and transcriptome analyses provide insights into the biology of the trematode human parasite Fasciolopsis buski
Many trematode parasites cause infection in humans and are thought to be a major public health problem. Their ecological diversity in different regions provides challenging questions on evolution of these organisms. In this report, we perform transcriptome analysis of the giant intestinal fluke…
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Northeast India Helminth Parasite Information Database (NEIHPID): Knowledge Base for Helminth Parasites
Most metazoan parasites that invade vertebrate hosts belong to three phyla: Platyhelminthes, Nematoda and Acanthocephala. Many of the parasitic members of these phyla are collectively known as helminths and are causative agents of many debilitating, deforming and lethal diseases of humans and…
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An evidence based efficacy and safety assessment of the ethnobiologicals against poisonous and non-poisonous bites used by the tribals of three westernmost districts of West Bengal, India: Anti-phospholipase A 2 and genotoxic effects
Introduction: To explore the ethnobiological wisdom of the tribals of three western districts of West Bengal, India against poisonous and non-poisonous bites and stings, a quantitative approach was adopted. These age-old yet unexplored knowledge can be utilized in finding lead-molecules against…
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Genetics and Molecular Mapping of Black Rot Resistance Locus Xca1bc on Chromosome B-7 in Ethiopian Mustard ( Brassica carinata A. Braun)
Black rot caused by Xanthomonas campestris pv. campestris (Pam.) Dowson is the most destructive disease of cauliflower causing huge loss to the farmers throughout the world. Since there are limited sources of resistance to black rot in B. oleracea (C genome Brassica), exploration of A and B genomes…
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Evaluation of Memory Enhancing Clinically Available Standardized Extract of Bacopa monniera on P-Glycoprotein and Cytochrome P450 3A in Sprague-Dawley Rats
Bacopa monniera is a traditional Ayurvedic herbal medicine used to treat various mental ailments from ancient times. Recently, chemically standardized alcoholic extract of Bacopa monniera (BM) has been developed and currently available as over the counter herbal remedy for memory enhancement in…
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Optimization of diosgenin extraction from Dioscorea deltoidea tubers using response surface methodology and artificial neural network modelling
Introduction: Dioscorea deltoidea var. deltoidea (Dioscoreaceae) is a valuable endangered plant of great medicinal and economic importance due to the presence of the bioactive compound diosgenin. In the present study, response surface methodology (RSM) and artificial neural network (ANN) modelling…
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Heat Shock Protein-70 (Hsp-70) Suppresses Paraquat-Induced Neurodegeneration by Inhibiting JNK and Caspase-3 Activation in Drosophila Model of Parkinson's Disease
Parkinson's disease (PD) is one of the most common neurodegenerative disorders with limited clinical interventions. A number of epidemiological as well as case-control studies have revealed an association between pesticide exposure, especially of paraquat (PQ) and occurrence of PD. Hsp70, a…
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Development of the Olfactory Epithelium and Nasal Glands in TMEM16A -/- and TMEM16A +/+ Mice
TMEM16A/ANO1 is a calcium-activated chloride channel expressed in several types of epithelia and involved in various physiological processes, including proliferation and development. During mouse embryonic development, the expression of TMEM16A in the olfactory epithelium is dynamic. TMEM16A is…
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Low prevalence of Plasmodium falciparum histidine-rich protein 2 and 3 gene deletions in malaria-endemic states of India
Rapid diagnostic tests (RDTs) are crucial for diagnosing malaria in resource-limited settings. These tests, which detect the histidine-rich protein 2 (PfHRP2) and its structural homologue PfHRP3, are specifically designed to identify Plasmodium falciparum. Deletion of the Pfhrp2 gene in parasite…
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Genome-wide association study uncovers key genomic regions governing agro-morphological and quality traits in Indian mustard [ Brassica juncea (L.) Czern. and Coss.]
In Indian mustard, improving agro-morphological and quality traits through conventional methods are both cumbersome and resource-intensive. Marker-aided breeding presents a promising solution to these challenges. Hence, the present research aimed to identify genomic regions governing…
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Yield optimization, microbial load analysis, and sensory evaluation of mungbean ( Vigna radiata L.), lentil ( Lens culinaris subsp. culinaris ), and Indian mustard ( Brassica juncea L.) microgreens grown under greenhouse conditions
Microgreens have been used for raw consumption and are generally viewed as healthy food. This study aimed to optimize the yield parameters, shelf life, sensory evaluation and characterization of total aerobic bacteria (TAB), yeast and mold (Y&M), Escherichia coli, Salmonella spp., and Listeria spp…
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Genetic differentiation among Aedes aegypti populations from different eco-geographical zones of India
The present study explicitly evaluated the genetic structure of Aedes aegypti Linn, the vector of dengue, chikungunya, and Zika viruses, across different geo-climatic zones of India and also elucidated the impact of ecological and topographic factors. After data quality checks and removal of…