36 hasil untuk "Dharmendra"
Menampilkan 1–20 · 0,33 detik · RSS
-
Artikel Jurnal Teks lengkap
A Conceptual Cortical Surface Atlas
Volumetric, slice-based, 3-D atlases are invaluable tools for understanding complex cortical convolutions. We present a simple scheme to convert a slice-based atlas to a conceptual surface atlas that is easier to visualize and understand. The key idea is to unfold each slice into a one-dimensional…
-
Artikel Jurnal Teks lengkap
Oxidative Stress and Nano-Toxicity Induced by TiO 2 and ZnO on WAG Cell Line
Metallic nanoparticles are widely used in cosmetics, food products and textile industry. These particles are known to cause respiratory toxicity and epithelial inflammation. They are eventually released to aquatic environment necessitating toxicity studies in cells from respiratory organs of…
-
Artikel Jurnal Teks lengkap
Cofilin Oligomer Formation Occurs In Vivo and Is Regulated by Cofilin Phosphorylation
Background: ADF/cofilin proteins are key regulators of actin dynamics. Their function is inhibited by LIMK-mediated phosphorylation at Ser-3. Previous in vitro studies have shown that dependent on its concentration, cofilin either depolymerizes F-actin (at low cofilin concentrations) or promotes…
-
Artikel Jurnal Teks lengkap
Multifaceted bioactivity of brown seaweed-derived fucoidan from the Indian Coastline: A natural health product candidate
Brown seaweeds are rich in bioactive constituents, among which fucoidan a sulphated polysaccharide is particularly noted for its broad-spectrum therapeutic properties. This study explores the multifaceted bioactivity of fucoidan extracted from six brown seaweed species (Sargassum wightii, Sargassum…
-
Artikel Jurnal Teks lengkap
Genomic Mechanisms Accounting for the Adaptation to Parasitism in Nematode-Trapping Fungi
Orbiliomycetes is one of the earliest diverging branches of the filamentous ascomycetes. The class contains nematode-trapping fungi that form unique infection structures, called traps, to capture and kill free-living nematodes. The traps have evolved differently along several lineages and include…
-
Artikel Jurnal Teks lengkap
Muscleblind-1 interacts with tubulin mRNAs to regulate the microtubule cytoskeleton in C . elegans mechanosensory neurons
Regulation of the microtubule cytoskeleton is crucial for the development and maintenance of neuronal architecture, and recent studies have highlighted the significance of regulated RNA processing in the establishment and maintenance of neural circuits. In a genetic screen conducted using…
-
Artikel Jurnal Teks lengkap
Associations of intimate partner violence and reproductive coercion with contraceptive use in Uttar Pradesh, India: How associations differ across contraceptive methods
Intimate partner violence (IPV) and reproductive coercion (RC)–largely in the form of pressuring pregnancy—appear to contribute to low use of contraceptives in India; however, little is known about the extent to which these experiences differentially affect use of specific contraceptive methods…
-
Artikel Jurnal Teks lengkap
Awareness of management of pulmonary multidrug-resistant tuberculosis (MDR-TB) among private practitioners in suburban areas of Pune city, India: Input for developing an educational tool
Private practitioners (PPs) play a major role in caring for people with tuberculosis (TB) in India. At the same time, PPs have limited access to continuing medical education and oversight especially with regards to recent changes in the management of multi-drug resistant (MDR- TB). As a part of a…
-
Artikel Jurnal Teks lengkap
Knockdown of FIBRILLIN4 Gene Expression in Apple Decreases Plastoglobule Plastoquinone Content
Fibrillin4 (FBN4) is a protein component of plastoglobules, which are antioxidant-rich sub-compartments attached to the chloroplast thylakoid membranes. FBN4 is required for normal plant biotic and abiotic stress resistance, including bacterial pathogens, herbicide, high light intensity, and ozone…
-
Artikel Jurnal Teks lengkap
Understanding intersections of social determinants of maternal healthcare utilization in Uttar Pradesh, India
Objective: To explore intersections of social determinants of maternal healthcare utilization using the Classification and Regression Trees (CART) algorithm which is a machine-learning method used to construct prediction models. Methods: Institutional review board approval for this study was…
-
Artikel Jurnal Teks lengkap
Differentiation of Induced Pluripotent Stem Cells to Lentoid Bodies Expressing a Lens Cell-Specific Fluorescent Reporter
Curative approaches for eye cataracts and other eye abnormalities, such as myopia and hyperopia currently suffer from a lack of appropriate models. Here, we present a new approach for in vitro growth of lentoid bodies from induced pluripotent stem (iPS) cells as a tool for ophthalmological…
-
Artikel Jurnal Teks lengkap
G10 is a direct activator of human STING
The cGAS/STING pathway initiates an innate immune response when DNA is detected in the cytosol. DNA bound cGAS synthesizes cyclic dinucleotides which bind and activate the adaptor STING, leading to downstream secretion of Type I interferons and other pro-inflammatory NFκB pathway cytokines. In the…
-
Artikel Jurnal Teks lengkap
Investigating host-virus interaction mechanism and phylogenetic analysis of viral proteins involved in the pathogenesis
Since the emergence of yellow fever in the Americas and the devastating 1918 influenza pandemic, biologists and clinicians have been drawn to human infecting viruses to understand their mechanisms of infection better and develop effective therapeutics against them. However, the complex molecular…
-
Artikel Jurnal Teks lengkap
Diagnosis of Visceral Leishmaniasis in Bihar India: Comparison of the rK39 Rapid Diagnostic Test on Whole Blood Versus Serum
Background: Antibody-detecting rapid diagnostic tests (RDTs) against rK39 are available to aid in the diagnosis of visceral leishmaniasis (VL). Although these rK39 RDTs have been developed, validated and approved for use with serum, they are universally performed using whole blood. It was therefore…
-
Artikel Jurnal Teks lengkap
Genetic Diversity in Lens Species Revealed by EST and Genomic Simple Sequence Repeat Analysis
Low productivity of pilosae type lentils grown in South Asia is attributed to narrow genetic base of the released cultivars which results in susceptibility to biotic and abiotic stresses. For enhancement of productivity and production, broadening of genetic base is essentially required. The genetic…
-
Artikel Jurnal Teks lengkap
Integrative network-centric approach reveals signaling pathways associated with plant resistance and susceptibility to Pseudomonas syringae
Plant protein kinases form redundant signaling pathways to perceive microbial pathogens and activate immunity. Bacterial pathogens repress cellular immune responses by secreting effectors, some of which bind and inhibit multiple host kinases. To understand how broadly bacterial effectors may bind…
-
Artikel Jurnal Teks lengkap
Investigating single amino acid substitutions in PIM1 kinase: A structural genomics approach
PIM1, is a serine/threonine proto-oncogene kinase, involved in many biological functions, including cell survival, proliferation, and differentiation, thus play a key role in oncogenesis. It plays a crucial role in the onset and progression of various hematopoietic and non-hematopoietic…
-
Artikel Jurnal Teks lengkap
The Metabolic Score for Visceral Fat (METS-VF) as a predictor of diabetes mellitus: Evidence from the 2011–2018 NHANES study
Introduction: With 42.4% of obese US population, the prevalence of diabetes mellitus (DM) is increasing. Visceral fat, even at the same body mass index, has significant deleterious effects. This study aims to investigate the association between the Metabolic Score for Visceral Fat (METS-VF) and DM…
-
Artikel Jurnal Teks lengkap
Missense Mutation of Brain Derived Neurotrophic Factor ( BDNF ) Alters Neurocognitive Performance in Patients with Mild Traumatic Brain Injury: A Longitudinal Study
The predictability of neurocognitive outcomes in patients with traumatic brain injury is not straightforward. The extent and nature of recovery in patients with mild traumatic brain injury (mTBI) are usually heterogeneous and not substantially explained by the commonly known demographic and…
-
Artikel Jurnal Teks lengkap
Associations between recent intimate partner violence and receipt and quality of perinatal health services in Uttar Pradesh
Background: India suffers some of the highest maternal and neonatal mortality rates in the world. Intimate partner violence (IPV) can be a barrier to utilization of perinatal care, and has been associated with poor maternal and neonatal health outcomes. However, studies that assess the relationship…