9 hasil untuk "E Lin"
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Artikel Jurnal Teks lengkap
The relationships among nurses’ spiritual health, sleep quality, and stress and the factors influencing stress during the late global COVID-19 pandemic: A cross- sectional study
Background: COVID-19 has had a significant impact on healthcare workers. Although several studies have looked at the pandemic’s physical and mental effects on nurses, little has been done to investigate their spiritual health and its relationship to stress and sleep quality during the late…
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Artikel Jurnal Teks lengkap
A sense of belonging: The role of higher education in retaining quality STEM teachers
There is an alarming shortage of qualified STEM teachers in American PK-12 schools. The COVID-19 pandemic may exacerbate this crisis and consequently affect who participates in future STEM innovation. At three points during the pandemic, we surveyed early career teachers who were supported by the…
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Artikel Jurnal Teks lengkap
A Novel CDX2 Isoform Regulates Alternative Splicing
Gene expression is a dynamic and coordinated process coupling transcription with pre-mRNA processing. This regulation enables tissue-specific transcription factors to induce expression of specific transcripts that are subsequently amplified by alternative splicing allowing for increased proteome…
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Artikel Jurnal Teks lengkap
The effects of the flipped classroom in teaching evidence based nursing: A quasi-experimental study
Background: Evidence-based nursing (EBN) has been an important training mechanism for improving the quality of clinical care. At present, the pedagogy focuses on the application of e-learning and team-based learning to enhance learners’ engagement and learning effectiveness. Objectives: This study…
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Artikel Jurnal Teks lengkap
Myeloid Cell Sirtuin-1 Expression Does Not Alter Host Immune Responses to Gram-Negative Endotoxemia or Gram-Positive Bacterial Infection
The role of sirtuin-1 (SIRT1) in innate immunity, and in particular the influence of SIRT1 on antimicrobial defense against infection, has yet to be reported but is important to define since SIRT1 inhibitors are being investigated as therapeutic agents in the treatment of cancer, Huntington’s…
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Artikel Jurnal Teks lengkap
Role of Hypoxia Inducible Factor-1α (HIF-1α) in Innate Defense against Uropathogenic Escherichia coli Infection
Uropathogenic E. coli (UPEC) is the primary cause of urinary tract infections (UTI) affecting approximately 150 million people worldwide. Here, we revealed the importance of transcriptional regulator hypoxia-inducible factor-1 α subunit (HIF-1α) in innate defense against UPEC-mediated UTI. The…
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Artikel Jurnal Teks lengkap
STAT1-mediated interferon signaling in the hematopoietic system is essential for restricting Usutu virus infection in vivo
Usutu virus (USUV) is an emerging mosquito-borne flavivirus known to induce neuroinvasive disease in birds, mice, and humans in European and African countries. The mechanisms of infection and dissemination remain poorly understood. Thus, elucidating how USUV spreads in a susceptible host is crucial…
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Artikel Jurnal Teks lengkap
The Association of Alternate VEGF Ligands with Resistance to Anti-VEGF Therapy in Metastatic Colorectal Cancer
Background: Circulating angiogenic factors are altered in patients with mCRC receiving bevacizumab. Evaluation of alterations in levels of VEGF ligands may provide insights into possible resistance mechanisms. Methods: PlGF, VEGF-A, VEGF-C, and VEGF-D were measured from two cohorts of patients…
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Artikel Jurnal Teks lengkap
Receptor transporter protein 4 (RTP4)-mediated repression of hepatitis C virus replication in mouse cells
Hepatitis C virus (HCV) exhibits a narrow species tropism, causing robust infections only in humans and experimentally inoculated chimpanzees. While many host factors and restriction factors are known, many more likely remain unknown, which has limited the development of mouse or other small animal…