8 hasil untuk "Feng-Chang Lin"
Menampilkan 1–8 · 0,38 detik · RSS
-
Artikel Jurnal Teks lengkap
Practical Implications of the Non-Linear Relationship between the Test Positivity Rate and Malaria Incidence
Background: The test positivity rate (TPR), defined as the number of laboratory-confirmed malaria tests per 100 suspected cases examined, is widely used by malaria surveillance programs as one of several key indicators of temporal trends in malaria incidence. However, there have been few studies…
-
Artikel Jurnal Teks lengkap
Multi-state models of transitions in depression and anxiety symptom severity and cardiovascular events in patients with coronary heart disease
Objective: Patients with coronary heart disease (CHD) commonly suffer from depression and anxiety, yet transitions of symptom severity and cardiovascular events (CVE) over time are not well characterized. Methods: We included 997 patients with stable CHD from a prospective cohort study. We…
-
Artikel Jurnal Teks lengkap
Diversity of T Cell Epitopes in Plasmodium falciparum Circumsporozoite Protein Likely Due to Protein-Protein Interactions
Circumsporozoite protein (CS) is a leading vaccine antigen for falciparum malaria, but is highly polymorphic in natural parasite populations. The factors driving this diversity are unclear, but non-random assortment of the T cell epitopes TH2 and TH3 has been observed in a Kenyan parasite…
-
Artikel Jurnal Teks lengkap
Alignment of PrEP adherence and HIV exposure risk among pregnant and postpartum women in Lilongwe, Malawi
Objective: When measured continuously, adherence to HIV pre-exposure prophylaxis (PrEP) is consistently low in studies of pregnant and postpartum women. We investigated how PrEP adherence aligned with HIV exposure risk. Methods: We conducted a trial of a PrEP adherence support intervention in…
-
Artikel Jurnal Teks lengkap
Efficacy of pyrazinoic acid dry powder aerosols in resolving necrotic and non-necrotic granulomas in a guinea pig model of tuberculosis
New therapeutic strategies are needed to treat drug resistant tuberculosis (TB) and to improve treatment for drug sensitive TB. Pyrazinamide (PZA) is a critical component of current first-line TB therapy. However, the rise in PZA-resistant TB cases jeopardizes the future utility of PZA. To address…
-
Artikel Jurnal Teks lengkap
Symptom burden, viral load, and antibody response to ancestral SARS-CoV-2 strain [D614G] in an outpatient household cohort
Background: Early in the SARS-CoV-2 pandemic, description of COVID-19 illness among non-hospitalized patients was limited. Data from household cohorts can help reveal the full spectrum of disease and the potential for long-term sequelae, even in non-severe disease. Methods: Daily symptom diaries…
-
Artikel Jurnal Teks lengkap
Real-time PCR detection of mixed Plasmodium ovale curtisi and wallikeri infections in human and mosquito hosts
Plasmodium ovale curtisi (Poc) and Plasmodium ovale wallikeri (Pow) represent distinct non-recombining Plasmodium species that are increasing in prevalence in sub-Saharan Africa. Though they circulate sympatrically, co-infection within human and mosquito hosts has rarely been described. Separate…
-
Artikel Jurnal Teks lengkap
Epidemiology of ovale, vivax and falciparum malaria in the highlands of Cameroon: An integrated community survey of human infection and vector abundance
Despite global malaria control efforts, the disease caused 263 million cases and 597,000 deaths in 2023. While Plasmodium falciparum accounts for most cases in Africa, non-falciparum species, such as P. ovale spp. and P. vivax, can cause relapse infections and are increasingly recognized as…