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4 results for "Filbert Francis"

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  1. Journal Article Full text

    Impact of treatment and re-treatment with artemether-lumefantrine and artesunate-amodiaquine on selection of Plasmodium falciparum multidrug resistance gene-1 polymorphisms in the Democratic Republic of Congo and Uganda

    Vito Baraka; Hypolite Muhindo Mavoko; Carolyn Nabasumba et al.

    PLOS ONE, Vol. 13 No. 2 · 2018 · English · PLOS Scopus

    Background: The emergence of resistance against artemisinin combination treatment is a major concern for malaria control. ACTs are recommended as the rescue treatment, however, there is limited evidence as to whether treatment and re-treatment with ACTs select for drug-resistant P. falciparum…

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  2. Journal Article Full text

    Impact of a bi-annual community-directed treatment with ivermectin programme on the incidence of epilepsy in an onchocerciasis-endemic area of Mahenge, Tanzania: A population-based prospective study

    Dan Bhwana; Luís-Jorge Amaral; Athanas Mhina et al.

    PLOS Neglected Tropical Diseases, Vol. 17 No. 6 · 2023 · English · PLOS Scopus

    Background: Community-directed treatment with ivermectin (CDTi) is used to eliminate onchocerciasis. However, despite 25 years of annual CDTi in Mahenge, Tanzania, the prevalence of onchocerciasis and onchocerciasis-associated epilepsy remained high in certain rural villages. Therefore, in 2019…

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  3. Journal Article Full text

    Molecular surveillance of malaria in Tanzania: Baseline surveillance of vectors that drive persistent malaria transmission in regions with varying transmission intensities

    Yahya A. Derua; Bernard M. Batengana; Filbert Francis et al.

    PLOS One, Vol. 21 No. 4 · 2026 · English · PLOS Scopus

    Malaria has remained persistently high in some regions of Tanzania despite increased control interventions. To address the burden of malaria in these regions, monitoring malaria vector dynamics is crucial to inform control interventions. This study assessed the composition and infectivity of…

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  4. Journal Article Full text

    Attributable risk factors for asymptomatic malaria and anaemia and their association with cognitive and psychomotor functions in schoolchildren of north-eastern Tanzania

    Geofrey Makenga; Vito Baraka; Filbert Francis et al.

    PLOS ONE, Vol. 17 No. 5 · 2022 · English · PLOS Scopus

    In Africa, children aged 5 to 15 years (school age) comprises more than 50% (>339 million) of the under 19 years population, and are highly burdened by malaria and anaemia that impair cognitive development. For the prospects of improving health in African citizens, understanding malaria and its…

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