6 hasil untuk "James Larkin"
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Artikel Jurnal Teks lengkap
The Predicted Impact of Ipilimumab Usage on Survival in Previously Treated Advanced or Metastatic Melanoma in the UK
Background: Evaluating long-term prognosis is important for physicians, patients and payers. This study reports the results of a model developed to predict long-term survival for UK patients receiving second-line ipilimumab. Methods: MDX010-20 trial data were used to predict survival for ipilimumab…
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Artikel Jurnal Teks lengkap
Understanding the social dimensions of kidney care pathways: A scoping review protocol
Objective: This scoping review aims to map the social dimensions of kidney care pathways. Introduction: End-stage kidney disease places significant demands on patients, caregivers, healthcare professionals, and the broader healthcare system. Kidney replacement therapy and conservative kidney…
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Artikel Jurnal Teks lengkap
Economic, cultural, and social inequalities in potentially inappropriate medication: A nationwide survey- and register-based study in Denmark
Background: Potentially inappropriate medication (PIM) is associated with negative health outcomes and can serve as an indicator of treatment quality. Previous studies have identified social inequality in treatment but often relied on narrow understandings of social position or failed to account…
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Artikel Jurnal Teks lengkap
Health-related quality of life with adjuvant immune checkpoint inhibition in renal cell carcinoma: A qualitative study of UK participants in the phase III RAMPART trial
Introduction: RAMPART is an international phase III trial evaluating adjuvant immune checkpoint inhibitors (ICIs) after nephrectomy for renal cell carcinoma. ICIs have a distinct toxicity profile that can significantly impact health-related quality of life (HRQoL); however existing HRQoL…
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Artikel Jurnal Teks lengkap
Common Variation at 1q24.1 ( ALDH9A1 ) Is a Potential Risk Factor for Renal Cancer
So far six susceptibility loci for renal cell carcinoma (RCC) have been discovered by genome-wide association studies (GWAS). To identify additional RCC common risk loci, we performed a meta-analysis of published GWAS (totalling 2,215 cases and 8,566 controls of Western-European background) with…
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Artikel Jurnal Teks lengkap
The influence of obesity-related factors in the etiology of renal cell carcinoma—A mendelian randomization study
Background: Several obesity-related factors have been associated with renal cell carcinoma (RCC), but it is unclear which individual factors directly influence risk. We addressed this question using genetic markers as proxies for putative risk factors and evaluated their relation to RCC risk in a…