26 hasil untuk "Jen-Der Lin"

Discovering Incidental Thyroid Disease by Imaging Studies

Jen-Der Lin

Journal of Medical Ultrasound, Vol. 23 No. 1 · 2015 · Inggris · DOAJ Scopus

Disease-specific mortality and secondary primary cancer in well-differentiated thyroid cancer with type 2 diabetes mellitus.

Szu-Tah Chen; Chuen Hsueh; Wen-Ko Chiou dkk.

PLoS ONE, Vol. 8 No. 1 · 2013 · Inggris · DOAJ Scopus

BACKGROUND: Increased body mass index is related to the incidence of thyroid cancer. However, the presentation and therapeutic outcomes of different thyroid cancers and type 2 diabetes mellitus (DM) have not been studied. This study investigated the effect of type 2 DM on the clinical presentations…

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Thyrotoxic periodic paralysis in an 81-year-old diabetes patient with insulin treatment

Sheng-Fong Kuo; Bie-Yui Huang; Ning-I Yang dkk.

Journal of the Formosan Medical Association, Vol. 111 No. 6 · 2012 · Inggris · DOAJ Scopus

Long-term therapeutic outcomes of papillary thyroid carcinoma with concomitant hyperparathyroidism: A single center case-control study

Chih-Yiu Tsai; Szu-Tah Chen; Chuen Hsueh dkk.

Biomedical Journal, Vol. 43 No. 1 · 2020 · Inggris · DOAJ Scopus

Background: Papillary thyroid carcinoma occasionally presents with concomitant hyperparathyroidism; however, the clinical significance has not been well established. This study aimed to evaluate the long-term cancer prognosis following a multimodality therapy. Methods: We conducted a case-control…

A cyclin-dependent kinase inhibitor, dinaciclib in preclinical treatment models of thyroid cancer.

Shu-Fu Lin; Jen-Der Lin; Chuen Hsueh dkk.

PLoS ONE, Vol. 12 No. 2 · 2017 · Inggris · DOAJ Scopus

We explored the therapeutic effects of dinaciclib, a cyclin-dependent kinase (CDK) inhibitor, in the treatment of thyroid cancer.Seven cell lines originating from three pathologic types of thyroid cancer (papillary, follicular and anaplastic) were studied. The cytotoxicity of dinaciclib was…

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Therapeutic Outcome of Second Primary Malignancies in Patients with Well-Differentiated Thyroid Cancer

Miaw-Jene Liou; Ngan-Ming Tsang; Chuen Hsueh dkk.

International Journal of Endocrinology, Vol. 2016 · 2016 · Inggris · DOAJ Scopus

Background. The aims of this study were to analyze the clinical characteristics of SPM in patients with well-differentiated thyroid cancer and to determine the long-term prognosis in patients with double malignancies. Materials and Methods. We retrospectively analyzed 2,864 patients with…

Gender-Specific Variation in the Prognosis of Papillary Thyroid Cancer TNM Stages II to IV

Sheng-Hwu Hsieh; Szu-Tah Chen; Chuen Hsueh dkk.

International Journal of Endocrinology, Vol. 2012 · 2012 · Inggris · DOAJ Scopus

To investigate the correlation between gender and the clinical presentation of papillary thyroid cancer and the long-term followup results, 435 patients who underwent total or near-total thyroidectomy were enrolled in this study. Among these papillary thyroid cancer patients, 12.2% showed lymph…

Utility of a histone deacetylase inhibitor (PXD101) for thyroid cancer treatment.

Shu-Fu Lin; Jen-Der Lin; Ting-Chao Chou dkk.

PLoS ONE, Vol. 8 No. 10 · 2013 · Inggris · DOAJ Scopus

BACKGROUND:We evaluated the therapeutic effects of the histone deacetylase inhibitor PXD101 alone and in combination with conventional chemotherapy in treating thyroid cancer. METHODOLOGY/PRINCIPAL FINDINGS:We studied eight cell lines from four types of thyroid cancer (papillary, follicular…

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Long-term follow-up of papillary and follicular thyroid carcinomas with bone metastasis.

Jen-Der Lin; Shu-Fu Lin; Szu-Tah Chen dkk.

PLoS ONE, Vol. 12 No. 3 · 2017 · Inggris · DOAJ Scopus

The aims of this study were to investigate papillary and follicular thyroid carcinomas with bone metastasis in various clinical presentations and to determine the prognostic factors after multimodality treatment. A retrospective analysis was performed of 3,120 patients with papillary and follicular…

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Risk factors of distant metastasis in the follicular variant of papillary thyroid carcinoma

Yan-Rong Li; Szu-Tah Chen; Chuen Hseuh dkk.

Journal of the Formosan Medical Association, Vol. 115 No. 8 · 2016 · Inggris · DOAJ Scopus

The follicular variant of papillary thyroid carcinoma (FVPTC) is the most common variant of papillary thyroid carcinoma (PTC). A previous population-based study revealed its clinical behavior as a mix of classic papillary thyroid carcinoma (C-PTC) and follicular thyroid carcinoma. Whereas…

Prognostic Evaluation of Patients With Multicentric Papillary Thyroid Microcarcinoma

Sheng-Fong Kuo; Tzu-Chieh Chao; Hung-Yu Chang dkk.

Journal of the Formosan Medical Association, Vol. 110 No. 8 · 2011 · Inggris · DOAJ Scopus

Patients with papillary thyroid microcarcinoma (PTMC) often have an excellent prognosis. We hypothesize that patients with multicentric PTMC are associated with good clinical outcome, although multicentricity in papillary thyroid carcinoma may be associated with poor prognosis. Methods…

Utility of a PI3K/mTOR inhibitor (NVP-BEZ235) for thyroid cancer therapy.

Shu-Fu Lin; Yu-Yao Huang; Jen-Der Lin dkk.

PLoS ONE, Vol. 7 No. 10 · 2012 · Inggris · DOAJ Scopus

BACKGROUND: We assessed the utility of the dual PI3K/mTOR inhibitor NVP-BEZ235 (BEZ235) as single agent therapy and in combination with conventional chemotherapy for thyroid cancer. METHODOLOGY/PRINCIPAL FINDINGS: Eight cell lines from four types of thyroid cancer (papillary, follicular…

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Prognosis of Multifocal Papillary Thyroid Carcinoma

Sheng-Fong Kuo; Shu-Fu Lin; Tzu-Chieh Chao dkk.

International Journal of Endocrinology, Vol. 2013 · 2013 · Inggris · DOAJ Scopus

This study was to investigate the clinical features and therapeutic outcomes of multifocal papillary thyroid microcarcinoma (PTMC). A total of 2,418 papillary thyroid carcinoma (PTC) patients had undergone thyroidectomy in one medical center between 1977 and 2010. There were 483 (20.0%) diagnosed…

Therapeutic Outcomes of Patients with Multifocal Papillary Thyroid Microcarcinomas and Larger Tumors

Soh-Ching Ng; Sheng-Fong Kuo; Szu-Tah Chen dkk.

International Journal of Endocrinology, Vol. 2017 · 2017 · Inggris · DOAJ Scopus

A retrospective review of 626 patients with multifocal papillary thyroid carcinoma (PTC) including 147 patients (23.5%) with multifocal papillary thyroid microcarcinoma (PTMC) from a total of 2,536 patients with PTC who visited the Chang Gung Medical Center in Linkou, Taiwan, was performed. A…

Subclinical hypothyroidism and metabolic risk factors association: A health examination-based study in northern Taiwan

Feng-Hsuan Liu; Jawl-Shan Hwang; Chang-Fu Kuo dkk.

Biomedical Journal, Vol. 41 No. 1 · 2018 · Inggris · DOAJ Scopus

Background: Subclinical hypothyroidism (SCH) is defined as elevation in serum thyroid-stimulating hormone (TSH) levels despite normal serum levels of free thyroxine. It remains controversial whether people with SCH have higher total cholesterol and low-density lipoprotein cholesterol levels…