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Multimodal profiling of lung granulomas in macaques reveals cellular correlates of tuberculosis control

Hannah Priyadarshini Gideon; Travis K. Hughes; Constantine N. Tzouanas dkk.

Immunity · 2022 · Inggris · OpenAlex Scopus

Mycobacterium tuberculosis lung infection results in a complex multicellular structure: the granuloma. In some granulomas, immune activity promotes bacterial clearance, but in others, bacteria persist and grow. We identified correlates of bacterial control in cynomolgus macaque lung granulomas by…