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Lactate: A key regulator of the immune response

Alba Llibre; Salih Kucuk; Atrayee Gope dkk.

Immunity · 2025 · Inggris · OpenAlex Scopus

Lactate, the end product of both anaerobic and aerobic glycolysis in proliferating and growing cells-with the latter process known as the Warburg effect-is historically considered a mere waste product of cell and tissue metabolism. However, research over the past ten years has unveiled multifaceted…

DAMPs and DAMP-sensing receptors in inflammation and diseases

Ming Ma; Wei Jiang; Rongbin Zhou

Immunity · 2024 · Inggris · OpenAlex Scopus

Bile acids modified by the intestinal microbiota promote colorectal cancer growth by suppressing CD8+ T cell effector functions

Jingjing Cong; Pianpian Liu; Zili Han dkk.

Immunity · 2024 · Inggris · OpenAlex Scopus

New frontiers in the cGAS-STING intracellular DNA-sensing pathway

Steve Dvorkin; Stephanie Cambier; Hannah E. Volkman dkk.

Immunity · 2024 · Inggris · OpenAlex Scopus

Glucose-driven histone lactylation promotes the immunosuppressive activity of monocyte-derived macrophages in glioblastoma

Alessandra De Leo; Alessio Ugolini; Xiaoqing Yu dkk.

Immunity · 2024 · Inggris · OpenAlex Scopus

Decoding Toll-like receptors: Recent insights and perspectives in innate immunity

Taro Kawai; Moe Ikegawa; Daisuke Ori dkk.

Immunity · 2024 · Inggris · OpenAlex Scopus

LAG-3, TIM-3, and TIGIT: Distinct functions in immune regulation

Nicole Joller; Ana Carrizosa Anderson; Vijay Kumar Kuchroo

Immunity · 2024 · Inggris · OpenAlex Scopus

Microenvironment-driven metabolic adaptations guiding CD8+ T cell anti-tumor immunity

Jaeoh Park; Pei‐Chun Hsueh; Zhiyu Li dkk.

Immunity · 2023 · Inggris · OpenAlex Scopus

The landscape of immune dysregulation in Crohn’s disease revealed through single-cell transcriptomic profiling in the ileum and colon

Lingjia Kong; Vladislav Pokatayev; Ariel J. Lefkovith dkk.

Immunity · 2023 · Inggris · OpenAlex Scopus

Hypoxic niches attract and sequester tumor-associated macrophages and cytotoxic T cells and reprogram them for immunosuppression

Anirudh Sattiraju; Sangjo Kang; Bruno Giotti dkk.

Immunity · 2023 · Inggris · OpenAlex Scopus

Principles of regulatory T cell function

Stanislav Dikiy; Alexander Yu Rudensky

Immunity · 2023 · Inggris · OpenAlex Scopus

CD8+ T cells in the cancer-immunity cycle

Josephine Ruth Giles; Anna-Maria Globig; Susan M. Kaech dkk.

Immunity · 2023 · Inggris · OpenAlex Scopus

Oxidative phosphorylation selectively orchestrates tissue macrophage homeostasis

Stefanie K. Wculek; Ignacio Heras‐Murillo; Annalaura Mastrangelo dkk.

Immunity · 2023 · Inggris · OpenAlex Scopus

Tertiary lymphoid structures and B cells: An intratumoral immunity cycle

Wolf H. Fridman; Maxime Meylan; Guilhem Pupier dkk.

Immunity · 2023 · Inggris · OpenAlex Scopus

Sex hormone signaling and regulation of immune function

Joseph P. Hoffmann; Jennifer A. Liu; Kumba Seddu dkk.

Immunity · 2023 · Inggris · OpenAlex Scopus

Dendritic cells as shepherds of T cell immunity in cancer

Mikaël J. Pittet; Mauro Di Pilato; Christopher Garris dkk.

Immunity · 2023 · Inggris · OpenAlex Scopus

The cancer-immunity cycle: Indication, genotype, and immunotype

Ira Mellman; Daniel S. Chen; Thomas B. Powles dkk.

Immunity · 2023 · Inggris · OpenAlex Scopus

The cancer-immunity cycle provides a framework to understand the series of events that generate anti-cancer immune responses. It emphasizes the iterative nature of the response where the killing of tumor cells by T cells initiates subsequent rounds of antigen presentation and T cell stimulation…

Gasdermin D permeabilization of mitochondrial inner and outer membranes accelerates and enhances pyroptosis

Rui Miao; Cong Jiang; Winston Chang dkk.

Immunity · 2023 · Inggris · OpenAlex Scopus

CXCR3 expression in regulatory T cells drives interactions with type I dendritic cells in tumors to restrict CD8+ T cell antitumor immunity

Mariela Alejandra Moreno Ayala; Timothy F. Campbell; Chen‐Yu Zhang dkk.

Immunity · 2023 · Inggris · OpenAlex Scopus

Cytokines as emerging regulators of central nervous system synapses

Frauke Zipp; Stefan Bittner; Dorothy P. Schafer

Immunity · 2023 · Inggris · OpenAlex Scopus