20 results for "Kumar Shantanu"
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Journal Article
Reinforcement learning-driven optimization of incentive-based demand response in distribution network with optimal placement of DG
Abstract Demand response (DR) is a key strategy for strengthening the economic efficiency, planning and operational stability of microgrids. This paper proposes an incentive-based DR program implemented through agent-based reinforcement learning, designed to optimize the profit of both the…
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Imaging Findings in Chiari I Malformation with Syringomyelia in a Case of Charcot Shoulder
Neuropathic arthropathy of the shoulder is reported in only 5% of cases. Here, we report a rare case of neuropathic arthropathy of the shoulder, secondary to Chiari malformation Type I with associated syringomyelia, that remained undetected for four years. A 38-year-old female presented to our…
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Hypervascular Pelvic Hemangiopericytoma Successfully Excised Without Embolization
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Presence of a Surface-Exposed Loop Facilitates Trypsinization of Particles of Sinsiro Virus, a Genogroup II.3 Norovirus
Noroviruses (NoVs) are the causative agents of nonbacterial acute gastroenteritis in humans. NoVs that belong to genogroup II (GII) are quite prevalent and prone to undergo recombination, and their three-dimensional structure is not yet known. Protein homology modeling of Sinsiro virus (SV), a…
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Bilateral Primary Aneurysmal Bone Cyst of Proximal Femur: A Rare Case Report
Aneurysmal bone cysts (ABC) are blood-filled, locally destructive, expansile lesions of the bone. ABC of the proximal femur is usually unilateral in presentation. As far as the English literature is concerned, there is no case report of bilateral involvement of the proximal femur by primary ABC. We…
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Insights into the fatty acid profile and taxonomy of the extremophilic moss Hedwigia emodica (Bryophyta, Hedwigiales, Hedwigiaceae)
Extremophilic mosses are known to produce a variety of long-chain polyunsaturated fatty acids in response to various abiotic stresses. These fatty acids facilitate in membrane fluidity, enabling their survival in extreme conditions. The present study investigates the fatty acid profile and taxonomy…
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Fate and plasticity of the epidermis in response to congenital activation of BRAF
Determining the developmental consequences of activated RAS and its downstream effectors is critical to understanding several congenital conditions caused by either germline or somatic mutations of the RAS pathway. Here we demonstrate that embryonic activation of BRAF in mouse ectoderm triggers…
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Multilevel noncontiguous spinal fractures in adolescent idiopathic scoliosis: A report of three cases
This is a report of three cases of patients with Adolescent Idiopathic Scoliosis who presented with multilevel noncontiguous fractures of the spine. Interestingly, the apical vertebrae of the scoliotic curve were involved in all these three cases. The first patient had a fracture at apical T7 of…
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Diversity of mosses (Bryophyta) in Pangi valley (Himachal Pradesh, India): an unexplored domain of northwestern Himalaya
Diversity of mosses of a unique and unexplored geographical location in Himalaya, the Pangi valley in Himachal Pradesh, India is investigated. A total of 49 moss species belonging to 21 families have been recorded, including Hedwigia emodica, the detail on the type specimen of which is uncertain…
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Abdominoscrotal Hydrocele with Intestinal Malrotation: A Rare Association
Abdominoscrotal hydrocele is an uncommon clinical entity and so is intestinal malrotation. We report a case of 15 year old boy who presented with lump in abdomen previously diagnosed as mesenteric cyst on ultrasound. A multislice CT scan and repeat ultrasound not only diagnosed the case as…
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Does serum albumin level affect the healing outcomes of simple diaphyseal tibial fractures?
Aims: To quantify the serum albumin level and its correlation with fracture healing progression and outcomes in adult patients. Settings and Design: A prospective cohort study at an institutional trauma center. Materials and Methods: A total of 50 adult patients with simple, fresh traumatic…
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A Comparative Study of the Results of the Anatomic Medial Portal and All-inside Arthroscopic Acl Reconstruction
Introduction: Many techniques of graft placement in Arthroscopic Anterior Cruciate Ligament (ACL) reconstruction is available nowa-days, like trans-tibial, anatomical accessory medial portal and anatomical all-inside technique. Aim: To compare the improvement in clinical status of patients treated…
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Phytochemical Profiling and In Silico Analyses Reveal Druglike Characteristics in the Moss Brachythecium salebrosum (Bryophyta, Brachytheciaceae)
Bryophytes have long been used as traditional medicine in many Asian countries, particularly China and India. They are known to possess a variety of phytochemicals with known medicinal properties. While bryophytes are broadly recognized for their medicinal potential, the moss Brachythecium…
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Quantifying Impact Damage Severity in Conventional, Hybrid and Natural-Based Composite Structures: An Acousto–Ultrasonics Approach
This study presents an approach to quantifying impact-induced damage severity in composites, focusing on synthetic carbon fibre-reinforced polymer (CFRP), natural flax fibre-reinforced polymer (FFRP) and hybrid fibre reinforced polymer (HFRP) composite of carbon and flax. The investigation aims to…
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Improved delivery of Cas9 protein/gRNA complexes using lipofectamine CRISPRMAX
OBJECTIVES: To identify the best lipid nanoparticles for delivery of purified Cas9 protein and gRNA complexes (Cas9 RNPs) into mammalian cells and to establish the optimal conditions for transfection. RESULTS: Using a systematic approach, we screened 60 transfection reagents using six commonly-used…
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Need of Revision of Lower Limb Amputations in a North Indian Tertiary Care Centre
Inrtoduction: Amputation of the extremity is a big challenge to mankind. Revision rate of primary amputations stands high despite of maximum care at tertiary care centres. The purpose of this study was to establish cause for the revision, identify preventable cause and to assess outcome of revision…
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Microsatellite markers of water buffalo, Bubalus bubalis - development, characterisation and linkage disequilibrium studies
BACKGROUND: Microsatellite markers are highly polymorphic and widely used in genome mapping and population genetic studies in livestock species. River buffalo, Bubalus bubalis is an economically important livestock species, though only a limited number of microsatellite markers have been reported…
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Efficient Generation of Human iPS Cells by a Synthetic Self-Replicative RNA
The generation of human induced Pluripotent Stem (iPS) cells holds great promise for development of regenerative medicine therapies to treat a wide range of human diseases. However, the generation of iPS cells in the absence of integrative DNA vectors remains problematic. Here we report a simple…
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Variant allele frequency enrichment analysis in vitro reveals sonic hedgehog pathway to impede sustained temozolomide response in GBM
Neoplastic cells of Glioblastoma multiforme (GBM) may or may not show sustained response to temozolomide (TMZ) chemotherapy. We hypothesize that TMZ chemotherapy response in GBM is predetermined in its neoplastic clones via a specific set of mutations that alter relevant pathways. We describe…