78 hasil untuk "Li Cen"

Gene 33/Mig6/ERRFI1, an Adapter Protein with Complex Functions in Cell Biology and Human Diseases

Xu, Dazhong; Li, Cen

Cells · 2021 · Inggris · PubMed Central

Gene 33 (also named Mig6, RALT, and ERRFI1) is an adapter/scaffold protein with a calculated molecular weight of about 50 kD. It contains multiple domains known to mediate protein–protein interaction, suggesting that it has the potential to interact with many cellular partners and have multiple…

Regulation of the SIAH2-HIF-1 Axis by Protein Kinases and Its Implication in Cancer Therapy

Xu, Dazhong; Li, Cen

Front Cell Dev Biol · 2021 · Inggris · PubMed Central

The cellular response to hypoxia is a key biological process that facilitates adaptation of cells to oxygen deprivation (hypoxia). This process is critical for cancer cells to adapt to the hypoxic tumor microenvironment resulting from rapid tumor growth. Hypoxia-inducible factor 1 (HIF-1) is a…

Polo-like kinase 3, hypoxic responses, and tumorigenesis

Xu, Dazhong; Dai, Wei; Li, Cen

Cell Cycle · 2017 · Inggris · PubMed Central

The cellular hypoxic response contributes to cell transformation and tumor progression. Hypoxia-inducible factor 1 (HIF-1) is a key transcription factor that mediates transcription of genes whose products are essential for cellular adaptation to hypoxia. The activity of HIF-1 is largely regulated…

Video Game Payment Trends: A Comparative Study Of Traditional Transactions And Microtransactions

Tony Wibowo; Victor Fernando; Li Cen

INSERT, Vol. 7 No. 1 · 2026 · Indonesia · DOAJ SINTA 3

Abstrak Industri video game telah mengalami perkembangan pesat dengan munculnya berbagai model monetisasi, termasuk pembelian langsung dan mikrotransaksi. Secara global, mikrotransaksi menjadi dominan, namun penelitian yang menyoroti persepsi gamer di Indonesia terhadap kedua model ini masih…

Study on the correlation between serum total cholesterol levels and suicidal ideation in patients with first-episode drug-naïve schizophrenia: a cross-sectional study

Wang, Jiale; Li, Cen; Zhang, Xiaojuan dkk.

Front Psychiatry · 2025 · Inggris · PubMed Central

BACKGROUND: The pathological physiology of schizophrenia (SZ) is associated with defects in biological energy metabolism. Abnormal blood lipid levels may influence the emergence of suicidal ideation (SI) in SZ. This study aims to evaluate the relationship between blood lipid levels, psychiatric…

Quantitative detection of enrofloxacin in chicken and pork by magnetic solid phase extraction and surface-enhanced Raman spectroscopy

WANG Panxue; WANG Li; LI Cen dkk.

Zhongguo shipin weisheng zazhi, Vol. 36 No. 5 · 2024 · Tionghoa · DOAJ Scopus

ObjectiveTo develop a rapid and quantitative method for the detection of enrofloxacin in chicken and pork using magnetic solid phase extraction （MSPE） combined with surface enhanced Raman spectroscopy （SERS）.MethodsMagnetic Fe3O4@ covalent organic framework （COF） nanocomposites were synthesized and…

Gene 33/Mig6 inhibits hexavalent chromium-induced DNA damage and cell transformation in human lung epithelial cells

Park, Soyoung; Li, Cen; Zhao, Hong dkk.

Oncotarget · 2016 · Inggris · PubMed Central

Hexavalent Chromium [Cr(VI)] compounds are human lung carcinogens and environmental/occupational hazards. The molecular mechanisms of Cr(VI) carcinogenesis appear to be complex and are poorly defined. In this study, we investigated the potential role of Gene 33 (ERRFI1, Mig6), a multifunctional…

Mutual regulation between Polo-like kinase 3 and SIAH2 E3 ubiquitin ligase defines a regulatory network that fine-tunes the cellular response to hypoxia and nickel

Li, Cen; Park, Soyoung; Zhang, Xiaowen dkk.

J Biol Chem · 2017 · Inggris · PubMed Central

Elevated cellular response to hypoxia, which contributes to cell transformation and tumor progression, is a prominent feature of malignant cells in solid tumors. Polo-like kinase 3 (Plk3) is a serine/threonine protein kinase known to inhibit the cellular response to hypoxia and tumorigenesis…

Hyperoxia induces alveolar epithelial cell apoptosis by regulating mitochondrial function through small mothers against decapentaplegic 3 (SMAD3) and extracellular signal-regulated kinase 1/2 (ERK1/2)

Jiang, Jun; Wang, Juan; Li, Cen dkk.

Bioengineered · 2021 · Inggris · PubMed Central

Oxygen therapy and mechanical ventilation are widely used to treat and manage neonatal emergencies in critically ill newborns. However, they are often associated with adverse effects and result in conditions such as chronic lung disease and bronchopulmonary dysplasia. Hence, aclear understanding of…

Reliable and Rapid Detection and Quantification of Enrofloxacin Using a Ratiometric SERS Aptasensor

Wang, Panxue; Wang, Li; Li, Cen dkk.

Molecules · 2022 · Inggris · PubMed Central

Reliable detection and quantification of antibiotic residues in food using surface-enhanced Raman spectroscopy remain challenging, since the intensities of SERS signals are vulnerable to matrix and experimental factors. In this work, a ratiometric SERS aptasensor using 6-Carboxyl-X-Rhodamine…

Alterations in physico-chemical properties, microstructure, sensory characteristics, and volatile compounds of red pepper (Capsicum annuum var. conoides) during various thermal drying durations

Li, Cen; Wu, Yongjun; Zhu, Qiyan dkk.

Food Chem X · 2024 · Inggris · PubMed Central

Red pepper (Capsicum annuum var. conoides) is commonly used for dried pepper production in China, and the drying process, particularly the during duration, profoundly affects its quality. The findings indicate that prolonged exposure to high temperatures during thermal drying results in significant…

Comparison of ovarian preservation versus oophorectomy on fertility outcomes in patients with endometriosis post-laparoscopic surgery: A prospective study

Zhou, Jin-Jin; Yu, Ke; Mao, Hai-Yan dkk.

World J Clin Cases · 2024 · Inggris · PubMed Central

BACKGROUND: Endometriosis is a chronic inflammatory condition affecting a significant proportion of women of reproductive age. Although laparoscopic surgery is commonly the preferred treatment, the decision to preserve or remove the ovaries remains controversial. Previous studies have yielded…

User-Centered Development of a Non-Halal Food Service Locator App

Li Cen; Albet Novendo; Mieko Huang Vincent dkk.

Jurnal Nasional Teknik Elektro dan Teknologi Informasi, Vol. 15 No. 2 · 2026 · Indonesia · DOAJ

The rapid growth of culinary tourism has increased demand for location-based applications that support specific dietary preferences. In Indonesia, particularly in Batam City, non-Muslim users often have trouble identifying non-halal food services due to the generalized nature of existing similar…

Effect of cooling rate on the size fluctuation of V-containing phases in Al-V master alloys

Meng Yi; Li Cen; Cao Leigang dkk.

MATEC Web of Conferences, Vol. 356 · 2022 · Prancis · DOAJ

To investigate the relationship between the solidification cooling rate and the size fluctuation of different V-containing phases, Al-4 wt. % V master alloys with various V-containing constituents were prepared at different cooling rates carried out by a wedge-shaped water-cooled copper mold, a…

SPSED: A Signal Peptide Secretion Efficiency Database

Peng, Chong; Guo, Yixue; Ren, Shaodong dkk.

Front Bioeng Biotechnol · 2022 · Inggris · PubMed Central

Improvement in Noodle Quality and Changes in Microstructure and Disulfide Bond Content through the Addition of Pepper Straw Ash Leachate

Li, Xinyang; Wu, Yongjun; Li, Cen dkk.

Foods · 2024 · Inggris · PubMed Central

Every year, a significant amount of pepper stalks are wasted due to low utilization. The ash produced from pepper stalks contains a significant amount of alkaline salts, which are food additives that can enhance the quality of noodles. Therefore, utilizing natural pepper straw ash to improve the…

An Improved ResNet-1d with Channel Attention for Tool Wear Monitor in Smart Manufacturing

Dong, Liang; Wang, Chensheng; Yang, Guang dkk.

Sensors (Basel) · 2023 · Inggris · PubMed Central

Tool wear is a key factor in the machining process, which affects the tool life and quality of the machined work piece. Therefore, it is crucial to monitor and diagnose the tool condition. An improved CaAt-ResNet-1d model for multi-sensor tool wear diagnosis was proposed. The ResNet18 structure…

A critical role for MSR1 in vesicular stomatitis virus infection of the central nervous system

Yang, Duomeng; Lin, Tao; Li, Cen dkk.

iScience · 2021 · Inggris · PubMed Central

Macrophage scavenger receptor 1 (MSR1) plays an important role in host defense to bacterial infections, M2 macrophage polarization, and lipid homeostasis. However, its physiological function in viral pathogenesis remains poorly defined. Herein, we report that MSR1 facilitates vesicular stomatitis…

Amortized Safe Active Learning for Real-Time Data Acquisition: Pretrained Neural Policies From Simulated Nonparametric Functions

Li, Cen-You; Toussaint, Marc; Rakitsch, Barbara dkk.

arXiv · 2025 · Inggris · arXiv

Safe active learning (AL) is a sequential scheme for learning unknown systems while respecting safety constraints during data acquisition. Existing methods often rely on Gaussian processes (GPs) to model the task and safety constraints, requiring repeated GP updates and constrained acquisition…

Chemical Compositions of Metals in Bhasmas and Tibetan Zuotai Are a Major Determinant of Their Therapeutic Effects and Toxicity

Liu, Jie; Zhang, Feng; Ravikanth, Velagapudi dkk.

Evid Based Complement Alternat Med · 2019 · Inggris · PubMed Central

Minerals are alchemically processed as Bhasmas in Ayurvedic medicines or as Zuotai in Tibetan medicines. Ayurveda is a knowledge system of longevity and considers the mineral elixir made from “nature” capable of giving humans perpetual life. Herbo-metallic preparations have a long history in the…