7 results for "Li-Na Mei"
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Case Report: An NTRK1 fusion-positive embryonal rhabdomyosarcoma: clinical presentations, pathological characteristics and genotypic analyses
Rhabdomyosarcoma (RMS) is a prevalent form of soft tissue sarcoma that primarily affects children. Pediatric RMS is characterized by two distinct histological variants: embryonal (ERMS) and alveolar (ARMS). ERMS is a malignant tumor with primitive characteristics resembling the phenotypic and…
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Analysis of DNA mismatch repair and microsatellite instability in molecular typing of endometrial carcinoma
DNA mismatch repair (MMR)/microsatellite instability (MSI) status is an indispensable biomarker for predicting immunotherapy response, screening for Lynch syndrome (LS), and molecularly classifying endometrial carcinoma (EC). To investigate the consistency and the causes of discordance among…
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A case report: identifying a novel variant in ELOC(TCEB1)-mutant renal cell carcinoma
ELOC(TCEB1)-mutant renal cell carcinoma [ELOC(TCEB1)-RCC] is a newly recognized type of RCC characterized by clear cell morphology and ELOC(TCEB1) gene mutation. We analyzed one case with a point mutation in TCEB1 c.218T>A (p.V73E), which is a novel mutation site and has not been reported in…
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Dietary ellagic acid inhibiting gastrointestinal pathogens by modulation of microbiome-metabolite-immune axis
Abstract Antibiotic-induced depletion of the gut microbiota facilitated the colonization of vancomycin-resistant Enterococci (VRE) in the gastrointestinal tract, and then increased patients' susceptibility to secondary infections. Ellagic acid, a major constituent of fruits and nuts, showed various…
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Identification and intra-genus conservation analysis of non-conventional peptides in hybrid poplar 84K
The functional roles of non-conventional peptides (NCPs) encoded by short open reading frames (sORFs) are increasingly recognized. However, their evolutionary conservation among closely related species remains largely unexplored. This study presented a genome-wide identification of NCPs in the…
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Transcriptional and epigenetic dynamics of sex determining gene PdFERR and MADS-box related genes during flower development in Populus deltoides
Manipulation of genes controlling sex differentiation, flower development, and flowering in poplar is pivotal to shortening the juvenile phase for a speed breeding system or eliminate flowering to reduce the dispersions of polluting pollens and hairy seeds. The sex-determining gene (PtARR17/PdFERR)…
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In vitro and in vivo evaluation of macromolecular prodrug GC-FUA based nanoparticle for hepatocellular carcinoma chemotherapy
A novel type of macromolecular prodrug delivery system is reported in this research. The N-galactosylated-chitosan-5-fluorouracil acetic acid conjugate (GC-FUA) based nanoparticle delivery system was evaluated in vitro and in vivo. Biocompatibility of GC-FUA-NPs was screened by BSA adsorption test…