95 hasil untuk "Ling Lin"

The experience of urgent dialysis patients with end-stage renal disease: A qualitative study

Min-Ling Lin; Kuei-Hui Chu

PLOS ONE, Vol. 17 No. 1 · 2022 · Inggris · PLOS Scopus

Purpose: Taiwan is among the countries with the highest global prevalence of chronic renal disease. However, when advised to undergo dialysis therapy, patients with end-stage renal disease often hesitate. Attitudes toward medication and Taiwanese cultures are the main reasons for this delay, and…

The characteristics and survival of second primary lung cancer after Hodgkin’s lymphoma: A comparison with first primary lung cancer using the SEER database

Ling Lin; Daquan Wang; Haizhu Chen

PLOS ONE, Vol. 18 No. 5 · 2023 · Inggris · PLOS Scopus

Objective: The study aimed to compare the characteristics and prognosis between patients with second primary lung cancer following Hodgkin’s lymphoma and those with primary lung cancer. Materials and methods: Using the SEER 18 database, the characteristics and prognosis were compared between the…

Correction: Let’s make it better: An updated model interpreting international student satisfaction in China based on PLS-SEM approach

Ling Lin; Zhengwei Huang; Bestoon Othman dkk.

PLOS ONE, Vol. 15 No. 11 · 2020 · Inggris · PLOS Scopus

Let’s make it better: An updated model interpreting international student satisfaction in China based on PLS-SEM approach

Ling Lin; Zhengwei Huang; Bestoon Othman dkk.

PLOS ONE, Vol. 15 No. 7 · 2020 · Inggris · PLOS Scopus

Research studying into student satisfaction has been developing in the light of customer satisfaction theory which considers perceived value and quality as important predictors of student satisfaction. But the importance of value co-creation is very much overlooked. Hence this study intends to…

Revealing the Molecular Mechanism of Gastric Cancer Marker Annexin A4 in Cancer Cell Proliferation Using Exon Arrays

Li-Ling Lin; Hsuan-Cheng Huang; Hsueh-Fen Juan

Public Library of Science · 2012 · Inggris · PLOS Scopus

Gastric cancer is a malignant disease that arises from the gastric epithelium. A potential biomarker for gastric cancer is the protein annexin A4 (ANXA4), an intracellular Ca2+ sensor. ANXA4 is primarily found in epithelial cells, and is known to be involved in various biological processes…

Four Common Vascular Endothelial Growth Factor Polymorphisms (−2578C>A, −460C>T, +936C>T, and +405G>C) in Susceptibility to Lung Cancer: A Meta-Analysis

Ling Lin; Kejian Cao; Wenhu Chen dkk.

PLoS ONE, Vol. 8 No. 10 · 2013 · Inggris · PLOS Scopus

Background and Objective: Vascular endothelial growth factor (VEGF) is one of the key initiators and regulators of angiogenesis and it plays a vital role in the onset and development of malignancy. The association between VEGF gene polymorphisms and lung cancer risk has been extensively studied in…

Short Sleep Duration Is Associated with Reduced Leptin, Elevated Ghrelin, and Increased Body Mass Index

Shahrad Taheri; Ling Lin; Diane Austin dkk.

PLoS Medicine, Vol. 1 No. 3 · 2004 · Inggris · PLOS Scopus

Background: Sleep duration may be an important regulator of body weight and metabolism. An association between short habitual sleep time and increased body mass index (BMI) has been reported in large population samples. The potential role of metabolic hormones in this association is unknown…

Catechol-O-Methyltransferase Val158Met Polymorphism Associates with Individual Differences in Sleep Physiologic Responses to Chronic Sleep Loss

Namni Goel; Siobhan Banks; Ling Lin dkk.

PLoS ONE, Vol. 6 No. 12 · 2011 · Inggris · PLOS Scopus

Background: The COMT Val158Met polymorphism modulates cortical dopaminergic catabolism, and predicts individual differences in prefrontal executive functioning in healthy adults and schizophrenic patients, and associates with EEG differences during sleep loss. We assessed whether the COMT Val158Met…

VdNUC-2 , the Key Regulator of Phosphate Responsive Signaling Pathway, Is Required for Verticillium dahliae Infection

Sheng Deng; Cai-yue Wang; Xin Zhang dkk.

PLOS ONE, Vol. 10 No. 12 · 2015 · Inggris · PLOS Scopus

In fungal cells, a phosphate (Pi) responsive signaling and metabolism (PHO) pathway regulates Pi-homeostasis. NUC-2/PHO81 and its homologs are one of the most important components in the regulation pathway. In soil-borne phytopathogenic fungus Verticillium dahliae, we identified a Neurospora crassa…

Visualizing the Attack of RNase Enzymes on Dendriplexes and Naked RNA Using Atomic Force Microscopy

Hosam G. Abdelhady; Yen-Ling Lin; Haiping Sun dkk.

PLoS ONE, Vol. 8 No. 4 · 2013 · Inggris · PLOS Scopus

Cationic polymers such as poly(amidoamine), PAMAM, dendrimers have been used to electrostatically complex siRNA molecules forming dendriplexes for enhancing the cytoplasmic delivery of the encapsulated cargo. However, excess PAMAM dendrimers is typically used to protect the loaded siRNA against…

Involvement of Phosphorylation of Adenosine 5′-Monophosphate-Activated Protein Kinase in PTTH-Stimulated Ecdysteroidogenesis in Prothoracic Glands of the Silkworm, Bombyx mori

Shi-Hong Gu; Yun-Chin Hsieh; Shun-Chieh Young dkk.

PLoS ONE, Vol. 8 No. 5 · 2013 · Inggris · PLOS Scopus

In this study, we investigated inhibition of the phosphorylation of adenosine 5′-monophosphate-activated protein kinase (AMPK) by prothoracicotropic hormone (PTTH) in prothoracic glands of the silkworm, Bombyx mori. We found that treatment with PTTH in vitro inhibited AMPK phosphorylation in time-…

Bone edema on magnetic resonance imaging is highly associated with low bone mineral density in patients with ankylosing spondylitis

Danmin Wang; Zhiduo Hou; Yao Gong dkk.

PLOS ONE, Vol. 12 No. 12 · 2017 · Inggris · PLOS Scopus

Objective: This study aimed to assess the relationship between bone marrow edema (BME) on magnetic resonance imaging (MRI) and bone mineral density (BMD) in patients with ankylosing spondylitis (AS). Methods: The study included 333 patients with AS who underwent BMD measurements and axial MRI…

New Phylogenetic Groups of Torque Teno Virus Identified in Eastern Taiwan Indigenes

Kuang-Liang Hsiao; Li-Yu Wang; Chiung-Ling Lin dkk.

PLOS ONE, Vol. 11 No. 2 · 2016 · Inggris · PLOS Scopus

Torque teno virus (TTV) is a single-stranded DNA virus highly prevalent in the world. It has been detected in eastern Taiwan indigenes with a low prevalence of 11% by using N22 region of which known to underestimate TTV prevalence excessively. In order to clarify their realistic epidemiology, we…

Capecitabine in Combination with Standard (Neo)Adjuvant Regimens in Early Breast Cancer: Survival Outcome from a Meta-Analysis of Randomized Controlled Trials

Ze-Chun Zhang; Qi-Ni Xu; Sui-Ling Lin dkk.

PLOS ONE, Vol. 11 No. 10 · 2016 · Inggris · PLOS Scopus

Capecitabine has been investigated in early breast cancer in several studies, but it was undefined that whether it could improve survival. To investigate whether the addition of capecitabine affected survival in patients with early breast cancer, a meta-analysis was conducted and overall survival…

Single-cell transcriptomics profiling reveals cellular origins and molecular drivers underlying melanoma brain metastasis

Jingxin Zeng; Ling Lin; Yangyang Ma dkk.

PLOS One, Vol. 20 No. 11 · 2025 · Inggris · PLOS Scopus

Melanoma brain metastasis (MBM) remains lethal with limited treatment efficacy. Meanwhile, the cellular origins and drivers of brain metastasis from melanoma have yet to be defined. Through integrated single-cell/single-nucleus RNA sequencing of 26 melanoma samples, we identified a…

Changes in postural sway and cortical activities after napping

Hui-Ya Chen; Li-Yuan Chen; Shu-Zon Lou dkk.

PLOS ONE, Vol. 20 No. 4 · 2025 · Inggris · PLOS Scopus

Lowered arousal state after napping may lead to poorer standing balance and the need to recalibrate the sensory organization system. This study aimed to examine the changes in postural sway and sensory associated cortical activities immediately after waking from a nap. A convenience sample of young…

Application of a SODOSM-based MCDM method for evaluating comprehensive fruit quality: A case study of pineapple

Ru Zhou; Ling Lin; Qi Li dkk.

PLOS One, Vol. 20 No. 9 · 2025 · Inggris · PLOS Scopus

This study constructs an evaluation index system and model by integrating objective evaluation methods such as the entropy weight method and TOPSIS with subjective evaluation methods like Delphi and AHP. By analyzed the scatter plots of the comprehensive quality evaluation values of commodity…

Preventive effects of folic acid on Zika virus-associated poor pregnancy outcomes in immunocompromised mice

Yogy Simanjuntak; Hui-Ying Ko; Yi-Ling Lee dkk.

PLOS Pathogens, Vol. 16 No. 5 · 2020 · Inggris · PLOS Scopus

Zika virus (ZIKV) infection may lead to congenital microcephaly and pregnancy loss in pregnant women. In the context of pregnancy, folic acid (FA) supplementation may reduce the risk of abnormal pregnancy outcomes. Intriguingly, FA may have a beneficial effect on the adverse pregnancy outcomes…

Post-Streptococcal Antibodies Are Associated with Metabolic Syndrome in a Population-Based Cohort

Adi Aran; Ling Lin; Laurel Ann Finn dkk.

PLoS ONE, Vol. 6 No. 9 · 2011 · Inggris · PLOS Scopus

Background: Streptococcal infections are known to trigger autoimmune disorders, affecting millions worldwide. Recently, we found an association between post-streptococcal autoantibodies against Protein Disulphide Isomerase (PDI), an enzyme involved in insulin degradation and insulin resistance…

Reducing Amyloid Plaque Burden via Ex Vivo Gene Delivery of an Aβ-Degrading Protease: A Novel Therapeutic Approach to Alzheimer Disease

Matthew L Hemming; Michaela Patterson; Casper Reske-Nielsen dkk.

PLoS Medicine, Vol. 4 No. 8 · 2007 · Inggris · PLOS Scopus

Background: Understanding the mechanisms of amyloid-β protein (Aβ) production and clearance in the brain has been essential to elucidating the etiology of Alzheimer disease (AD). Chronically decreasing brain Aβ levels is an emerging therapeutic approach for AD, but no such disease-modifying agents…