9 hasil untuk "Linlin Deng"
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Artikel Jurnal
The Mechanism of Acrylamide-Induced Neurotoxicity: Current Status and Future Perspectives
Acrylamide (ACR), a potential neurotoxin, is produced by the Maillard reaction between reducing sugars and free amino acids during food processing. Over the past decade, the neurotoxicity of ACR has caused increasing concern, prompting many related studies. This review summarized the relevant…
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Artikel Jurnal
Targeting the secretory autophagy–extracellular vesicle interface: fate decisions and translational opportunities
Autophagy preserves cellular homeostasis through lysosomal degradation, but its machinery also participates in extracellular release. This creates a pharmacological problem: changing autophagy or extracellular vesicle (EV) output can alter intracellular disposal, inflammatory signaling and…
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Artikel Jurnal
Measurement of multiple mechanical properties for polymer composites using digital image correlation at elevated temperatures
This work presents a cost-effective experimental method for measuring multiple mechanical properties for carbon fiber reinforced modified epoxy matrix composites using the digital image correlation method at elevated temperatures. The method is based on combining a calculated stress distribution…
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Artikel Jurnal
Current landscape of BRD4 inhibitors: Selective targeting and protein degradation for enhanced efficacy
The bromodomain and extra-terminal domain (BET) family of proteins has been implicated as a crucial factor in the pathogenesis of numerous diseases by regulating gene expression and chromatin dynamics through its bromodomains, which bind to acetylated lysine residues. As a key member of the BET…
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Artikel Jurnal Teks lengkap
Evaluating Free PPV23 Vaccination for the Elderly in Nanning, China: A Cost-Effectiveness Analysis
Background: This study aims to evaluate the cost-effectiveness of providing the 23-valent pneumococcal polysaccharide vaccine (PPV23) free of charge versus self-paying vaccination among adults aged 60 years and older in Nanning, Guangxi, China. Methods: A decision tree–Markov model was developed to…
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Artikel Jurnal
Economic evaluation of including the EV71 vaccine in the national immunization program: a modeling study in Guangxi, China
BackgroundHand, foot, and mouth disease (HFMD) remains a major public health concern among children in China, particularly in those under 5 years of age. Enterovirus 71 (EV71) is the leading cause of severe cases and mortality. Although EV71 vaccines are highly effective, they are currently…