2 hasil untuk "Madison Butler"

MGMT Status as a Clinical Biomarker in Glioblastoma

Madison Butler; Lőrinc Sándor Pongor; Yuting Su dkk.

Trends in cancer · 2020 · Inggris · OpenAlex Scopus

Identifying and exploiting combinatorial synthetic lethality by characterizing adaptive kinome rewiring of EGFRvIII-driven glioblastoma

Benjamin Lin; Abigail K. Shelton; Erin Smithberger dkk.

Acta Neuropathologica Communications, Vol. 13 No. 1 · 2025 · Inggris · DOAJ Scopus

Abstract GBM is an aggressive primary malignant brain tumor that has a poor prognosis. Molecular characterization of GBM has shown that EGFR mutations are present in over 50% of tumors. However, EGFR inhibitors have not shown clinical efficacy in contrast to other EGFR-driven neoplasms due to the…