19 hasil untuk "Marc Decramer"
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Tiotropium HandiHaler® in the treatment of COPD: A safety review
Steven Kesten1, Bart Celli2, Marc Decramer3, Inge Leimer4, Donald Tashkin51Boehringer Ingelheim Pharmaceuticals; Ridgefield, CT, USA; 2Caritas St. Elizabeth’s Medical Center, Boston, MA, USA; 3University of Leuven, Leuven, Belgium; 4Boehringer Ingelheim GmbH, Ingelheim, Germany; 5David Geffen…
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Perspectives using probe-based confocal laser endomicroscopy of the respiratory tract
QUESTIONS UNDER STUDY/PRINCIPLES: Although probe-based confocal laser endomicroscopy (pCLE) is on the edge of entering daily practice in gastroenterological endoscopy, findings in the field of respiratory medicine are only rarely reported, keeping pCLE during flexible bronchoscopy as a mere…
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Possíveis conseqüências de não se atingir a mínima atividade física diária recomendada em pacientes com doença pulmonar obstrutiva cronica estável Potential consequences for stable chronic obstructive pulmonary disease patients who do not get the recommended minimum daily amount of physical activity
OBJETIVO: O presente estudo investigou se pacientes com Doença Pulmonar Obstrutiva Crônica (DPOC) atingem a mínima atividade física recomendada pelos guidelines do American College of Sports Medicine (ACSM), assim como as consequências da não-aderência a esses guidelines. MÉTODOS: Atividade física…
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Proprioceptive Changes Impair Balance Control in Individuals with Chronic Obstructive Pulmonary Disease
Introduction: Balance deficits are identified as important risk factors for falling in individuals with chronic obstructive pulmonary disease (COPD). However, the specific use of proprioception, which is of primary importance during balance control, has not been studied in individuals with COPD…
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Physical Activity Counselling during Pulmonary Rehabilitation in Patients with COPD: A Randomised Controlled Trial
Background: Pulmonary rehabilitation programs only modestly enhance daily physical activity levels in patients with chronic obstructive pulmonary disease (COPD). This randomised controlled trial investigates the additional effect of an individual activity counselling program during pulmonary…
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Correction: Physical Activity Counselling during Pulmonary Rehabilitation in Patients with COPD: A Randomised Controlled Trial
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Two Distinct Chronic Obstructive Pulmonary Disease (COPD) Phenotypes Are Associated with High Risk of Mortality
Rationale: In COPD patients, mortality risk is influenced by age, severity of respiratory disease, and comorbidities. With an unbiased statistical approach we sought to identify clusters of COPD patients and to examine their mortality risk. Methods: Stable COPD subjects (n = 527) were classified…
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Long-term nose-only cigarette smoke exposure induces emphysema and mild skeletal muscle dysfunction in mice
SUMMARY Mouse models of chronic obstructive pulmonary disease (COPD) focus on airway inflammation and lung histology, but their use has been hampered by the lack of pulmonary function data in their assessment. Systemic effects such as muscle dysfunction are also poorly modeled in emphysematous…
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Impaired Postural Control Reduces Sit-to-Stand-to-Sit Performance in Individuals with Chronic Obstructive Pulmonary Disease
Background: Functional activities, such as the sit-to-stand-to-sit (STSTS) task, are often impaired in individuals with chronic obstructive pulmonary disease (COPD). The STSTS task places a high demand on the postural control system, which has been shown to be impaired in individuals with COPD. It…
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Moderate Intense Physical Activity Depends on Selected Metabolic Equivalent of Task (MET) Cut-Off and Type of Data Analysis
Background: Accelerometry data are frequently analyzed without considering whether moderate-to-vigorous physical activities (MVPA) were performed in bouts of >10 minutes as defined in most physical activity guidelines. We aimed i) to quantify MVPA by using different commonly-applied physical…
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Variants in the 15q24/25 Locus Associate with Lung Function Decline in Active Smokers
Genetic variation in nicotinic acetylcholine receptor subunit genes (nAChRs) is associated with lung function level and chronic obstructive pulmonary disease (COPD). It is unknown whether these variants also predispose to an accelerated lung function decline. We investigated the association of…
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An official American Thoracic Society/European Respiratory Society statement: research questions in COPD
Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity, mortality and resource use worldwide. The goal of this official American Thoracic Society (ATS)/European Respiratory Society (ERS) Research Statement is to describe evidence related to diagnosis, assessment, and…