6 hasil untuk "Meng-Han Lin"

Cholesterol affected dynamics of lipids in tailor-made vesicles by ArcVes software during multi micro second coarse grained molecular dynamics simulations

Chia-Wen Wang; Meng-Han Lin

AIMS Biophysics, Vol. 10 No. 4 · 2023 · Inggris · DOAJ Scopus

In biotechnology, as well as in nanomedicine, vesicular structures are essential features of the cellular life cycle. Lipid compositions define the applicability of the vesicles. Here, the dynamics of lipid molecules within vesicles of approximately 10 nm in diameter are monitored using…

A Taiwanese Patient with Multiple Epiphyseal Dysplasia Type 1 was Found to have Novel Mutation of Cartilage Oligomeric Matrix Protein: A Case Report

Meng-Han Lin; Wei-Hsun Wang

Formosan Journal of Musculoskeletal Disorders, Vol. 16 No. 3 · 2025 · Inggris · DOAJ

COMPopathies, caused by COMP gene mutations, include multiple epiphyseal dysplasia type 1 (MED type 1) and pseudoachondroplasia, typically manifesting as short stature, joint pain, hypermobility, and gait disturbances. While clinical and radiographic features guide initial diagnosis, genetic…

iStable 2.0: Predicting protein thermal stability changes by integrating various characteristic modules

Chi-Wei Chen; Meng-Han Lin; Chi-Chou Liao dkk.

Computational and Structural Biotechnology Journal, Vol. 18 · 2020 · Inggris · DOAJ Scopus

Protein mutations can lead to structural changes that affect protein function and result in disease occurrence. In protein engineering, drug design or and optimization industries, mutations are often used to improve protein stability or to change protein properties while maintaining stability. To…

Neurotrophic Effect of Citrus 5-Hydroxy-3,6,7,8,3′,4′-Hexamethoxyflavone: Promotion of Neurite Outgrowth via cAMP/PKA/CREB Pathway in PC12 Cells

Hui-Chi Lai; Ming-Jiuan Wu; Pei-Yi Chen dkk.

PLoS ONE, Vol. 6 No. 11 · 2011 · Inggris · PLOS Scopus

5-Hydroxy-3,6,7,8,3′,4′-hexamethoxyflavone (5-OH-HxMF), a hydroxylated polymethoxyflavone, is found exclusively in the Citrus genus, particularly in the peels of sweet orange. In this research, we report the first investigation of the neurotrophic effects and mechanism of 5-OH-HxMF in PC12…

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Developmental validation of FaSTR™ DNA: Software for the analysis of forensic DNA profiles

Meng-Han Lin; Shan-I Lee; Xinlong Zhang dkk.

Forensic Science International: Reports, Vol. 3 · 2021 · Inggris · DOAJ Scopus

The analysis of forensic DNA profiles is complicated by the presence of undesirable artefactual peaks such as stutter, pull-up, and dye blobs. We describe the developmental validation of FaSTR™ DNA analysis software, which can assist with the streamlined analysis of forensic DNA profiles. A total…