25 hasil untuk "Naresh Kumar"

Individual Skills Based Volunteerism and Life Satisfaction among Healthcare Volunteers in Malaysia: Role of Employer Encouragement, Self-Esteem and Job Performance, A Cross-Sectional Study

Chanthiran Veerasamy; Murali Sambasivan; Naresh Kumar

PLoS ONE, Vol. 8 No. 10 · 2013 · Inggris · PLOS Scopus

The purpose of this paper is to analyze two important outcomes of individual skills-based volunteerism (ISB-V) among healthcare volunteers in Malaysia. The outcomes are: job performance and life satisfaction. This study has empirically tested the impact of individual dimensions of ISB-V along with…

Pyocyanin Facilitates Extracellular DNA Binding to Pseudomonas aeruginosa Influencing Cell Surface Properties and Aggregation

Theerthankar Das; Samuel K. Kutty; Naresh Kumar dkk.

PLoS ONE, Vol. 8 No. 3 · 2013 · Inggris · PLOS Scopus

Pyocyanin is an electrochemically active metabolite produced by the human pathogen Pseudomonas aeruginosa. It is a recognized virulence factor and is involved in a variety of significant biological activities including gene expression, maintaining fitness of bacterial cells and biofilm formation…

Pseudomonas fluorescens ATCC 13525 Containing an Artificial Oxalate Operon and Vitreoscilla Hemoglobin Secretes Oxalic Acid and Solubilizes Rock Phosphate in Acidic Alfisols

Kavita Yadav; Chanchal Kumar; G. Archana dkk.

PLoS ONE, Vol. 9 No. 4 · 2014 · Inggris · PLOS Scopus

Oxalate secretion was achieved in Pseudomonas fluorescens ATCC 13525 by incorporation of genes encoding Aspergillus niger oxaloacetate acetyl hydrolase (oah), Fomitopsis plaustris oxalate transporter (FpOAR) and Vitreoscilla hemoglobin (vgb) in various combinations. Pf (pKCN2) transformant…

Association of TLR5 Gene Polymorphisms in Ulcerative Colitis Patients of North India and Their Role in Cytokine Homeostasis

Naresh Kumar Meena; Vineet Ahuja; Kusumlata Meena dkk.

PLOS ONE, Vol. 10 No. 3 · 2015 · Inggris · PLOS Scopus

Background and Aim: In health, TLR signaling protects the intestinal epithelial barrier and in disease, aberrant TLR signaling stimulates diverse inflammatory responses. Association of TLR polymorphisms is ethnicity dependent but how they impact the complex pathogenesis of IBD is not clearly…

Correction: Association of miR-196a-2 and miR-499 variants with ulcerative colitis and their correlation with expression of respective miRNAs

Raju Ranjha; Naresh Kumar Meena; Abhiraman Singh dkk.

PLOS ONE, Vol. 12 No. 9 · 2017 · Inggris · PLOS Scopus

Fetal Kidney Cells Can Ameliorate Ischemic Acute Renal Failure in Rats through Their Anti-Inflammatory, Anti-Apoptotic and Anti-Oxidative Effects

Ashwani Kumar Gupta; Sachin H Jadhav; Naresh Kumar Tripathy dkk.

PLOS ONE, Vol. 10 No. 6 · 2015 · Inggris · PLOS Scopus

Fetal kidney cells may contain multiple populations of kidney stem cells and thus appear to be a suitable cellular therapy for the treatment of acute renal failure (ARF) but their biological characteristics and therapeutic potential have not been adequately explored. We have culture expanded fetal…

Association of miR-196a-2 and miR-499 variants with ulcerative colitis and their correlation with expression of respective miRNAs

Raju Ranjha; Naresh Kumar Meena; Abhiraman Singh dkk.

PLOS ONE, Vol. 12 No. 3 · 2017 · Inggris · PLOS Scopus

Background and aim: MicroRNAs are small non-coding RNAs that play an important role in regulating the gene expression of their target genes. SNP miR-196a-2 rs11614913 and miR-499 rs3746444 are reported to have association with the risk and prognosis of multiple-types of inflammatory diseases…

Artificial Citrate Operon Confers Mineral Phosphate Solubilization Ability to Diverse Fluorescent Pseudomonads

Hemanta Adhikary; Paulomi B. Sanghavi; Silviya R. Macwan dkk.

PLoS ONE, Vol. 9 No. 9 · 2014 · Inggris · PLOS Scopus

Citric acid is a strong acid with good cation chelating ability and can be very efficient in solubilizing mineral phosphates. Only a few phosphate solubilizing bacteria and fungi are known to secrete citric acids. In this work, we incorporated artificial citrate operon containing NADH insensitive…

COVID-19 market disruptions and food security: Evidence from households in rural Liberia and Malawi

Shilpa Aggarwal; Dahyeon Jeong; Naresh Kumar dkk.

PLOS ONE, Vol. 17 No. 8 · 2022 · Inggris · PLOS Scopus

We use data collected from panel phone surveys to document the changes in food security of households in rural Liberia and Malawi during the market disruptions associated with the COVID-19 lockdowns in 2020. We use two distinct empirical approaches in our analysis: (a) an event study around the…

Derepression of Mineral Phosphate Solubilization Phenotype by Insertional Inactivation of iclR in Klebsiella pneumoniae

Mahendrapal Singh Rajput; Bhagya Iyer; Maharshi Pandya dkk.

PLOS ONE, Vol. 10 No. 9 · 2015 · Inggris · PLOS Scopus

The mode of succinate mediated repression of mineral phosphate solubilization and the role of repressor in suppressing phosphate solubilization phenotype of two free-living nitrogen fixing Klebsiella pneumoniae strains was studied. Organic acid mediated mineral phosphate solubilization phenotype of…

Normative Database of Retinal Oximetry in Asian Indian Eyes

Ashwin Mohan; Supriya Dabir; Naresh Kumar Yadav dkk.

PLOS ONE, Vol. 10 No. 4 · 2015 · Inggris · PLOS Scopus

Objective: To study the oxygen saturation profile in normal Asian Indian eyes. Design: A cross sectional prospective study. Subjects: Ninety eight consecutive patients presenting to our hospital with best corrected distance visual acuity (BCVA) of 20/20 and a normal ophthalmic examination were…

TAM Receptors Support Neural Stem Cell Survival, Proliferation and Neuronal Differentiation

Rui Ji; Lingbin Meng; Xin Jiang dkk.

PLoS ONE, Vol. 9 No. 12 · 2014 · Inggris · PLOS Scopus

Tyro3, Axl and Mertk (TAM) receptor tyrosine kinases play multiple functional roles by either providing intrinsic trophic support for cell growth or regulating the expression of target genes that are important in the homeostatic regulation of immune responses. TAM receptors have been shown to…

Rational Design, Synthesis, and Biological Evaluation of Third Generation α-Noscapine Analogues as Potent Tubulin Binding Anti-Cancer Agents

Naresh Kumar Manchukonda; Pradeep Kumar Naik; Seneha Santoshi dkk.

PLoS ONE, Vol. 8 No. 10 · 2013 · Inggris · PLOS Scopus

Systematic screening based on structural similarity of drugs such as colchicine and podophyllotoxin led to identification of noscapine, a microtubule-targeted agent that attenuates the dynamic instability of microtubules without affecting the total polymer mass of microtubules. We report a new…

Ocular Fluid As a Replacement for Serum in Cell Cryopreservation Media

Vivek Phani Varma; Lalitha Devi; Naresh Kumar Venna dkk.

PLOS ONE, Vol. 10 No. 7 · 2015 · Inggris · PLOS Scopus

Cryostorage is of immense interest in biomedical research, especially for stem cell-based therapies and fertility preservation. Several protocols have been developed for efficient cryopreservation of cells and tissues, and a combination of dimethyl sulfoxide (DMSO) and fetal bovine serum (FBS) is…

Using machine learning to understand microgeographic determinants of the Zika vector, Aedes aegypti

Jagger Alexander; André Barretto Bruno Wilke; Alejandro Mantero dkk.

PLOS ONE, Vol. 17 No. 12 · 2022 · Inggris · PLOS Scopus

There are limited data on why the 2016 Zika outbreak in Miami-Dade County, Florida was confined to certain neighborhoods. In this research, Aedes aegypti, the primary vector of Zika virus, are studied to examine neighborhood-level differences in their population dynamics and underlying processes…

Potential impact of efflux pump genes in mediating rifampicin resistance in clinical isolates of Mycobacterium tuberculosis from India

Anshika Narang; Kushal Garima; Shraddha Porwal dkk.

PLOS ONE, Vol. 14 No. 9 · 2019 · Inggris · PLOS Scopus

Despite the consideration of chromosomal mutations as the major cause of rifampicin (RIF) resistance in M. tuberculosis, the role of other mechanisms such as efflux pumps cannot be ruled out. We evaluated the role of four efflux pumps viz., MmpL2 (Rv0507), MmpL5 (Rv0676c), Rv0194 and Rv1250 in…

Host outdoor exposure variability affects the transmission and spread of Zika virus: Insights for epidemic control

Marco Ajelli; Imelda K. Moise; Tricia Caroline S. G. Hutchings dkk.

PLOS Neglected Tropical Diseases, Vol. 11 No. 9 · 2017 · Inggris · PLOS Scopus

Background: Zika virus transmission dynamics in urban environments follow a complex spatiotemporal pattern that appears unpredictable and barely related to high mosquito density areas. In this context, human activity patterns likely have a major role in Zika transmission dynamics. This paper…

Larvicidal toxicity of Metarhizium anisopliae metabolites against three mosquito species and non-targeting organisms

Perumal Vivekanandhan; Kannan Swathy; Dharman Kalaimurugan dkk.

PLOS ONE, Vol. 15 No. 5 · 2020 · Inggris · PLOS Scopus

Background: The fungal toxin acts as effective, low-cost chemical substances for pest control worldwide and also an alternative to synthetic insecticides. This study assessed the larvicidal potential of Metarhizium anisopliae fungi derived metabolites against Aedes aegypti, Anopheles stephensi…

Deciphering the change in root system architectural traits under limiting and non-limiting phosphorus in Indian bread wheat germplasm

Palaparthi Dharmateja; Manjeet Kumar; Rakesh Pandey dkk.

PLOS ONE, Vol. 16 No. 10 · 2021 · Inggris · PLOS Scopus

The root system architectures (RSAs) largely decide the phosphorus use efficiency (PUE) of plants by influencing the phosphorus uptake. Very limited information is available on wheat’s RSAs and their deciding factors affecting phosphorus uptake efficiency (PupE) due to difficulties in adopting…

Synthesis and Evaluation of the 2-Aminothiazoles as Anti-Tubercular Agents

Edward A. Kesicki; Mai A. Bailey; Yulia Ovechkina dkk.

PLOS ONE, Vol. 11 No. 5 · 2016 · Inggris · PLOS Scopus

The 2-aminothiazole series has anti-bacterial activity against the important global pathogen Mycobacterium tuberculosis. We explored the nature of the activity by designing and synthesizing a large number of analogs and testing these for activity against M. tuberculosis, as well as eukaryotic…