8 hasil untuk "Pascal Cohen"

Score to assess the probability of relapse in granulomatosis with polyangiitis and microscopic polyangiitis

Hervé Devilliers; Luc Mouthon; Pascal Cohen dkk.

RMD Open, Vol. 9 No. 1 · 2023 · Inggris · DOAJ Scopus

Objective To develop a score assessing the probability of relapse in granulomatosis with polyangiitis (GPA) and microscopic polyangiitis (MPA).Methods Long-term follow-up data from GPA and MPA patients included in five consecutive randomised controlled trials were pooled. Patient characteristics at…

Comparison of rituximab induction and maintenance regimens in anti-neutrophil cytoplasmic antibodies (ANCA)-associated vasculitis: PK/PD modelling of ANCA and gammaglobulin levels in real-world patientsResearch in context

Blaise Pasquiers; Benoit Blanchet; Xavier Puéchal dkk.

EBioMedicine, Vol. 121 · 2025 · Inggris · DOAJ Scopus

Summary: Background: We aimed to provide pharmacokinetic-pharmacodynamic (PK/PD) rationale for selecting the optimal induction and maintenance dosing regimens in ANCA-associated vasculitis (AAV) using a population modelling approach based on PK, ANCA, and gammaglobulins data from a real-world…

Autoantibodies versus Skin Fibrosis Extent in Systemic Sclerosis: A Case-Control Study of Inverted Phenotypes

Ashley Tieu; Benjamin Chaigne; Bertrand Dunogué dkk.

Diagnostics, Vol. 12 No. 5 · 2022 · Inggris · DOAJ Scopus

Objective: to describe the prevalences, characteristics, and survivals of patients with anti-topoisomerase 1 antibodies (ATA) and limited cutaneous systemic sclerosis (lSSc) and anti-centromere antibodies (ACA) and diffuse cutaneous systemic sclerosis (dSSc). Methods: patients with ATA lSSc or with…

Comparative study of granulomatosis with polyangiitis subsets according to ANCA status: data from the French Vasculitis Study Group Registry

Eric Hachulla; Luc Mouthon; Michele Iudici dkk.

RMD Open, Vol. 8 No. 1 · 2022 · Inggris · DOAJ Scopus

Unravelling IPAF, VEDOSS and connective tissue diseases classifications through the mixed connective tissue disease spectrum

Patrice Cacoub; Eric Hachulla; Nathalie Costedoat-Chalumeau dkk.

RMD Open, Vol. 11 No. 4 · 2025 · Inggris · DOAJ Scopus

Background Mixed connective tissue disease (MCTD) has long been debated as an early nonspecific phase/symptom of differentiated connective tissue diseases (dCTD), similarly to interstitial pneumonia with autoimmune features (IPAF) and very early diagnosis of systemic sclerosis (SSc)…

Concordance between presenting features and relapse in granulomatosis with polyangiitis: implications for risk assessment and counselling

Vincent Cottin; Eric Hachulla; Luc Mouthon dkk.

RMD Open, Vol. 11 No. 4 · 2025 · Inggris · DOAJ Scopus

Objective To investigate the concordance between organ involvement at diagnosis and relapse in granulomatosis with polyangiitis and factors associated with new disease features at relapse.Methods Data from a national database of newly diagnosed patients was analysed. Clinical features were recorded…

Factors associated with patient-reported likelihood of using online self-care interventions: a Scleroderma Patient-centered Intervention Network (SPIN) cohort study

Thierry Martin; Carter Thorne; Brett D Thombs dkk.

BMJ Open, Vol. 9 No. 10 · 2019 · Inggris · DOAJ Scopus

Objectives The Scleroderma Patient-centered Intervention Network (SPIN) Cohort uses the cohort multiple randomised controlled trial design to embed trials of online self-care interventions for people living with systemic sclerosis (SSc; scleroderma). To offer interventions to patients interested in…

Assessing differential item functioning for the Social Appearance Anxiety Scale: a Scleroderma Patient-centred Intervention Network (SPIN) Cohort Study

Arsène Mekinian; Thierry Martin; Eric Hachulla dkk.

BMJ Open, Vol. 10 No. 10 · 2020 · Inggris · DOAJ Scopus

Objectives The Social Appearance Anxiety Scale (SAAS) is a 16-item questionnaire developed to evaluate fear of appearance-based evaluation by others. The primary objective of this research was to investigate the existence of differential item functioning (DIF) for the 16 SAAS items, comparing…