6 hasil untuk "Patrick Doherty"
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Artikel Jurnal Teks lengkap
The effectiveness of modern cardiac rehabilitation: A systematic review of recent observational studies in non-attenders versus attenders
Background: The beneficial effects of cardiac rehabilitation (CR) have been challenged in recent years and there is now a need to investigate whether current CR programmes, delivered in the context of modern cardiology, still benefit patients. Methods: A systematic review of non-randomised…
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Artikel Jurnal Teks lengkap
Transcriptional Basis for the Inhibition of Neural Stem Cell Proliferation and Migration by the TGFβ-Family Member GDF11
Signalling through EGF, FGF and endocannabinoid (eCB) receptors promotes adult neurogenesis, and this can be modelled in culture using the Cor-1 neural stem cell line. In the present study we show that Cor-1 cells express a TGFβ receptor complex composed of the ActRIIB/ALK5 subunits and that a…
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Artikel Jurnal Teks lengkap
Metacognitive therapy home-based self-help for anxiety and depression in cardiovascular disease patients in the UK: A single-blind randomised controlled trial
Background: Anxiety and depression in cardiac rehabilitation (CR) are associated with greater morbidity, mortality, and increased healthcare costs. Current psychological interventions within CR have small effects based on low-quality studies of clinic-based interventions with limited access to…
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Artikel Jurnal Teks lengkap
“It’s a slightly different vibe”. New pathways in condition-specific rehabilitation for people with new or existing joint pain
Background: Musculoskeletal (MSK) conditions are a leading cause of pain and disability in adults. Exercise-based rehabilitation programmes are recommended however, sustained behaviour change is often poor. New rehabilitation pathways designed to promote adherence to exercise, can be iteratively…
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Artikel Jurnal Teks lengkap
Targeted Lipidomics in Drosophila melanogaster Identifies Novel 2-Monoacylglycerols and N -acyl Amides
Lipid metabolism is critical to coordinate organ development and physiology in response to tissue-autonomous signals and environmental cues. Changes to the availability and signaling of lipid mediators can limit competitiveness, adaptation to environmental stressors, and augment pathological…
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Artikel Jurnal Teks lengkap
Drebrin Regulates Neuroblast Migration in the Postnatal Mammalian Brain
After birth, stem cells in the subventricular zone (SVZ) generate neuroblasts that migrate along the rostral migratory stream (RMS) to become interneurons in the olfactory bulb (OB). This migration is crucial for the proper integration of newborn neurons in a pre-existing synaptic network and is…