49 hasil untuk "Peter Proff"
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Artikel Jurnal
Impact of different pretreatments and attachment materials on shear bond strength between monolithic zirconia restorations and metal brackets
Abstract To investigate the influence of different pretreatment methods, attachment materials and artificial aging on shear bond strength (SBS) between monolithic zirconia and metal brackets. Zirconia substrates were pretreated with silica coated alumina (CoJet) and (1) clearfill ceramic primer…
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Artikel Jurnal
Applying Automated Artificial Intelligence Models on Lateral Cephalometric Parameters to Accurately Classify Arab Orthodontic Patient Patterns
ABSTRACT Objectives Malocclusion and the treatment process can affect the person's quality of life, which includes physical and psychological effects. Classifying the patient accurately is critical to achieving the desired output. This study aimed to improve the current diagnostic process with…
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Artikel Jurnal
Predictors of changes in incisor inclination during orthodontic levelling and alignment with fixed appliances: a retrospective cross-sectional study
Abstract Introduction Labial tipping of the incisors, observed during levelling and alignment in orthodontic treatment with multibracket-appliances, can be an undesired side effect due to its association with relapse and attachment loss in excessive cases. Therefore, its pre-treatment prediction is…
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Artikel Jurnal
Comparative assessment of mouse models for experimental orthodontic tooth movement
Abstract Animal experiments are essential for the elucidation of biological-cellular mechanisms in the context of orthodontic tooth movement (OTM). So far, however, no studies comparatively assess available mouse models regarding their suitability. OTM of first upper molars was induced in C57BL/6…
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Artikel Jurnal
Comparative treatment outcomes after bilateral extractions of maxillary second molars or first premolars in patients with class II malocclusion: a retrospective study
Abstract Background This retrospective cohort study aimed to compare treatment results between bilateral extraction of upper second molars (M2) and first premolars (P1) in terms of treatment timing, cephalometry, upper third molar alignment and relapse in the long-term. Methods Fifty-three…
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Artikel Jurnal Teks lengkap
Housekeeping gene validation for RT-qPCR studies on synovial fibroblasts derived from healthy and osteoarthritic patients with focus on mechanical loading.
Selection of appropriate housekeeping genes is essential for the validity of data normalization in reverse transcription quantitative PCR (RT-qPCR). Synovial fibroblasts (SF) play a mediating role in the development and progression of osteoarthritis (OA) pathogenesis, but there is no information on…
Juga tersedia di: PLOS
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Artikel Jurnal
Relapse in class II orthognathic surgery: a systematic review
Abstract Objectives Relapse after orthognathic surgery seems to depend on diverse factors. Proffit et al. postulated in 2007 a “hierarchy of stability” (Head Face Med 6:66, 2007), ranking posttreatment stability after various orthognathic procedures, but no systematically reviewed evidence was…
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Artikel Jurnal
Effects of the Highly COX-2-Selective Analgesic NSAID Etoricoxib on Human Periodontal Ligament Fibroblasts during Compressive Orthodontic Mechanical Strain
Human periodontal ligament (hPDL) fibroblasts play a major role during periodontitis and orthodontic tooth movement, mediating periodontal inflammation, osteoclastogenesis, and collagen synthesis. The highly COX-2-selective NSAID etoricoxib has a favorable systemic side effect profile and high…
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Artikel Jurnal Teks lengkap
Effects of histamine on human periodontal ligament fibroblasts under simulated orthodontic pressure.
As type-I-allergies show an increasing prevalence in the general populace, orthodontic patients may also be affected by histamine release during treatment. Human periodontal ligament fibroblasts (PDLF) are regulators of orthodontic tooth movement. However, the impact of histamine on PDLF in this…
Juga tersedia di: PLOS
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Artikel Jurnal Teks lengkap
Effects of Histamine Receptor Antagonist Cetirizine on Orthodontic Tooth Movement
Many patients regularly take histamine receptor antagonists, such as cetirizine, to prevent allergic reactions, but these antiallergic drugs may have inadvertent effects on orthodontic treatment. In previous studies, histamine has been shown to modulate the sterile inflammatory reaction underlying…
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Artikel Jurnal Teks lengkap
Myeloid HIF1α Is Involved in the Extent of Orthodontically Induced Tooth Movement
During orthodontic tooth movement, transcription factor hypoxia-inducible factor 1α (HIF1α) is stabilised in the periodontal ligament. While HIF1α in periodontal ligament fibroblasts can be stabilised by mechanical compression, in macrophages pressure application alone is not sufficient to…
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Artikel Jurnal Teks lengkap
Association Between Single-Nucleotide Polymorphisms and DRAM1 Gene Expression in Periodontal Ligament Fibroblasts Under Orthodontic Compression
Background/Objectives: Autophagy is a key degradative pathway involved in orthodontic tooth movement. DNA damage-regulated autophagy modulator 1 (DRAM1), a protein that plays a central role in the degradation of autophagic cargo, exhibits differential regulation in human periodontal ligament (hPDL)…
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Artikel Jurnal
Role of Oxygen Supply in Macrophages in a Model of Simulated Orthodontic Tooth Movement
Apart from periodontal ligament fibroblasts, immune cells like macrophages also play an important mediating role in orthodontic tooth movement (OTM). Upon orthodontic force application to malpositioned teeth, macrophages in the periodontal ligament get exposed to both mechanical strain and hypoxic…
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Artikel Jurnal
Predictors of disease alleviation with mandibular advancement devices in obstructive sleep apnea: a retrospective cohort study
Abstract Background Obstructive sleep apnea (OSA) can be treated with mandibular advancement devices (MAD), preventing collapse of the upper airway and decreasing apnea-hypopnea index (AHI)/ h. Disease alleviation is expected to vary depending on specific predictors including OSA-severity and…
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Artikel Jurnal Teks lengkap
Local Vascularization during Orthodontic Tooth Movement in a Split Mouth Rat Model—A MRI Study
Orthodontic tooth movement to therapeutically align malpositioned teeth is supposed to impact blood flow in the surrounding tissues. Here, we evaluated actual vascularization in the tension area of the periodontal ligament during experimental tooth movement in rats (N = 8) with magnetic resonance…
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Artikel Jurnal
Curvature-dependent shear bond strength of different attachment materials for orthodontic lingual indirect bonding
Abstract To evaluate the shear bond strength (SBS) of different attachment materials used for lingual bonding, the influence of artificial aging and the radii of curvature of the enamel surface on SBS, 192 third molars were photographed to determine the radius of curvature of the oral surface…
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Artikel Jurnal
Effects of Compressive and Tensile Strain on Macrophages during Simulated Orthodontic Tooth Movement
During orthodontic tooth movement (OTM) to therapeutically correct the position of misaligned teeth, thus improving oral health and quality of life, fibroblasts, macrophages, and other immune cells within the periodontal ligament (PDL), which connects a tooth to its surrounding bone, are exposed to…
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Artikel Jurnal
The role of 25-hydroxyvitamin-D3 and vitamin D receptor gene in human periodontal ligament fibroblasts as response to orthodontic compressive strain: an in vitro study
Abstract Background This study aimed to investigate, if different physiological concentrations of vitamin D (25(OH)D3) and single nucleotide polymorphisms in vitamin D receptor (VDR) gene have an impact on gene expression in human periodontal ligament (hPDL) fibroblasts induced by simulated…