34 hasil untuk "Qing Lin"

The Characteristics of Chinese Orthographic Neighborhood Size Effect for Developing Readers

Jing Zhao; Qing-Lin Li; Hong-Yan Bi

Public Library of Science · 2012 · Inggris · PLOS Scopus

Orthographic neighborhood size (N size) effect in Chinese character naming has been studied in adults. In the present study, we aimed to explore the developmental characteristics of Chinese N size effect. One hundred and seventeen students (40 from the 3rd grade with mean age of 9 years; 40 from…

Parental Effect of Long Acclimatization on Thermal Tolerance of Juvenile Sea Cucumber Apostichopus japonicus

Qing-lin Wang; Shan-shan Yu; Yun-wei Dong

PLOS ONE, Vol. 10 No. 11 · 2015 · Inggris · PLOS Scopus

To evaluate the thermal resistance of marine invertebrates to elevated temperatures under scenarios of future climate change, it is crucial to understand parental effect of long acclimatization on thermal tolerance of offspring. To test whether there is parental effect of long acclimatization…

The different outcomes between breast-conserving surgery plus radiotherapy and mastectomy in metaplastic breast cancer: A population-based study

Lin-Yu Xia; Wei-Yun Xu; Qing-Lin Hu

PLOS ONE, Vol. 16 No. 9 · 2021 · Inggris · PLOS Scopus

Background: Metaplastic breast cancer (MBC) are rare. The survival outcomes of MBC patients after breast conserving surgery plus radiotherapy (BCS+RT) or mastectomy have not been established. The study aimed to compare survival outcomes of MBC patients subjected to BCS+RT or mastectomy therapeutic…

Physiological Responses in a Variable Environment: Relationships between Metabolism, Hsp and Thermotolerance in an Intertidal-Subtidal Species

Yun-wei Dong; Shan-shan Yu; Qing-lin Wang dkk.

PLoS ONE, Vol. 6 No. 10 · 2011 · Inggris · PLOS Scopus

Physiological responses to temperature reflect the evolutionary adaptations of organisms to their thermal environment and the capability of animals to tolerate thermal stress. Contrary to conventional metabolism theory, increasing environmental temperatures have been shown to reduce metabolic rate…

A Novel Selenocystine-Accumulating Plant in Selenium-Mine Drainage Area in Enshi, China

Linxi Yuan; Yuanyuan Zhu; Zhi-Qing Lin dkk.

PLoS ONE, Vol. 8 No. 6 · 2013 · Inggris · PLOS Scopus

Plant samples of Cardamine hupingshanesis (Brassicaceae), Ligulariafischeri (Ledeb.) turcz (Steraceae) and their underlying top sediments were collected from selenium (Se) mine drainage areas in Enshi, China. Concentrations of total Se were measured using Hydride Generation-Atomic Fluorescence…

Low pH-Induced Changes of Antioxidant Enzyme and ATPase Activities in the Roots of Rice ( Oryza sativa L.) Seedlings

Yi-Kai Zhang; De-Feng Zhu; Yu-Ping Zhang dkk.

PLOS ONE, Vol. 10 No. 2 · 2015 · Inggris · PLOS Scopus

Soil acidification is the main problem in the current rice production. Here, the effects of low pH on the root growth, reactive oxygen species metabolism, plasma membrane functions, and the transcript levels of the related genes were investigated in rice seedlings (Oryza sativa L.) in a hydroponic…

A monoclonal antibody targeting amyloid β (Aβ) restores complement factor I bioactivity: Potential implications in age-related macular degeneration and Alzheimer’s disease

Kameran Lashkari; Gianna Teague; Hong Chen dkk.

PLOS ONE, Vol. 13 No. 5 · 2018 · Inggris · PLOS Scopus

Activation of the alternative complement cascade has been implicated in the pathogenesis of age related macular degeneration (AMD) and Alzheimer’s disease (AD). Amyloid β (Aβ), a component of drusen, may promote complement activation by inhibiting CFI bioactivity. We determined whether Aβ reduced…

Risk Factors for Subdural Haematoma in Patients with Spontaneous Intracranial Hypotension

Ping Xia; Xing-Yue Hu; Jin Wang dkk.

PLOS ONE, Vol. 10 No. 4 · 2015 · Inggris · PLOS Scopus

Subdural haematoma (SDH) is a potentially life-threatening complication in patients with spontaneous intracranial hypotension (SIH). In serious cases, SIH patients who present with SDHs develop neurological deficits, a decreased level of consciousness, or cerebral herniation, and may even require…

An Experimental Analysis of the Molecular Effects of Trastuzumab (Herceptin) and Fulvestrant (Falsodex), as Single Agents or in Combination, on Human HR+/HER2+ Breast Cancer Cell Lines and Mouse Tumor Xenografts

Qing Chen; Ziyi Weng; Yunshu Lu dkk.

PLOS ONE, Vol. 12 No. 1 · 2017 · Inggris · PLOS Scopus

Purpose: To investigate the effects of trastuzumab (herceptin) and fulvestrant (falsodex) either in combination or alone, on downstream cell signaling pathways in lab-cultured human HR+/HER2+ breast cancer cell lines ZR-75-1 and BT-474, as well as on protein expression levels in mouse xenograft…

Systemic evaluation and localization of resistin expression in normal human tissues by a newly developed monoclonal antibody

Qing Lin; Shari A. Price; John T. Skinner dkk.

PLOS ONE, Vol. 15 No. 7 · 2020 · Inggris · PLOS Scopus

Resistin and resistin-like molecules are pleiotropic cytokines that are involved in inflammatory diseases. Our previous work suggested that resistin has the potential to be used as a biomarker and therapeutic target for human pulmonary arterial hypertension. However, data are limited on the…

Correction: An Experimental Analysis of the Molecular Effects of Trastuzumab (Herceptin) and Fulvestrant (Falsodex), as Single Agents or in Combination, on Human HR+/HER2+ Breast Cancer Cell Lines and Mouse Tumor Xenografts

Qing Chen; Ziyi Weng; Yunshu Lu dkk.

PLOS ONE, Vol. 19 No. 9 · 2024 · Inggris · PLOS Scopus

Human resistin is critical to activation of the NLRP3 inflammasome in macrophages

Udeshika Kariyawasam; Winson Lam; John Skinner dkk.

PLOS One, Vol. 21 No. 4 · 2026 · Inggris · PLOS Scopus

Elevated levels of human resistin (hResistin) have been associated with diverse inflammatory diseases, but the precise mechanisms through which hResistin’s many inflammatory effects contribute to the progression of these diseases remain poorly understood. NLRP3 inflammasome activation is essential…

Assessing the causal link between liver function and acute pancreatitis: A Mendelian randomisation study

Chun Zhang; Feng Lin; Deng-fang Guo dkk.

PLOS ONE, Vol. 19 No. 4 · 2024 · Inggris · PLOS Scopus

A correlation has been reported to exist between exposure factors (e.g. liver function) and acute pancreatitis. However, the specific causal relationship remains unclear. This study aimed to infer the causal relationship between liver function and acute pancreatitis using the Mendelian…

Cloning and Characterization of a Novel Vacuolar Na + /H + Antiporter Gene ( Dgnhx1 ) from Chrysanthemum

Qing-Lin Liu; Ke-Dong Xu; Ming Zhong dkk.

PLoS ONE, Vol. 8 No. 12 · 2013 · Inggris · PLOS Scopus

Plant vacuolar Na+/H+ antiporter genes play significant roles in salt tolerance. However, the roles of the chrysanthemum vacuolar Na+/H+ antiporter genes in salt stress response remain obscure. In this study, we isolated and characterized a novel vacuolar Na+/H+ antiporter gene DgNHX1 from…

Metabolic Impact of Adult-Onset, Isolated, Growth Hormone Deficiency (AOiGHD) Due to Destruction of Pituitary Somatotropes

Raul M. Luque; Qing Lin; José Córdoba-Chacón dkk.

PLoS ONE, Vol. 6 No. 1 · 2011 · Inggris · PLOS Scopus

Growth hormone (GH) inhibits fat accumulation and promotes protein accretion, therefore the fall in GH observed with weight gain and normal aging may contribute to metabolic dysfunction. To directly test this hypothesis a novel mouse model of adult onset-isolated GH deficiency (AOiGHD) was…

Disappearance of GFP-Positive Hepatocytes Transplanted into the Liver of Syngeneic Wild-Type Rats Pretreated with Retrorsine

Hiromichi Maeda; Masatoshi Shigoka; Yongchun Wang dkk.

PLoS ONE, Vol. 9 No. 5 · 2014 · Inggris · PLOS Scopus

Background and Aim: Green fluorescent protein (GFP) is a widely used molecular tag to trace transplanted cells in rodent liver injury models. The differing results from various previously reported studies using GFP could be attributed to the immunogenicity of GFP. Methods: Hepatocytes were obtained…

Oxygen-Carbon Nanotubes as a Chemotherapy Sensitizer for Paclitaxel in Breast Cancer Treatment

Yongkun Wang; Chuanying Wang; Yijun Jia dkk.

PLoS ONE, Vol. 9 No. 8 · 2014 · Inggris · PLOS Scopus

Objective: To study the in vivo and in vitro effects of adding oxygen carbon nanotubes (CNTs) to chemotherapy for breast cancer. Methods: MCF-7 and SK-BR-3 breast cancer cells were co-cultured with paclitaxel and then exposed to oxygen-CNTs under hypoxic conditions. Cell proliferation, viability…

Croton tiglium essential oil compounds have anti-proliferative and pro-apoptotic effects in A549 lung cancer cell lines

Qing-lin Niu; Hui Sun; Chao Liu dkk.

PLOS ONE, Vol. 15 No. 5 · 2020 · Inggris · PLOS Scopus

As a traditional Chinese medicine, Croton tiglium has the characteristics of laxative, analgesic, antibacterial and swelling. This study aimed to analyze the chemical composition of C. tiglium essential oil (CTEO) extracted from the seeds of C. tiglium and its cytotoxicity and antitumor effect in…

Cardiac Dysregulation and Myocardial Injury in a 6-Hydroxydopamine-Induced Rat Model of Sympathetic Denervation

Yue-Hua Jiang; Ping Jiang; Jin-long Yang dkk.

PLOS ONE, Vol. 10 No. 7 · 2015 · Inggris · PLOS Scopus

Background: Cardiac sympathetic denervation is found in various cardiac pathologies; however, its relationship with myocardial injury has not been thoroughly investigated. Methods: Twenty-four rats were assigned to the normal control group (NC), sympathectomy control group (SC), and a sympathectomy…

Clear Genetic Distinctiveness between Human- and Pig-Derived Trichuris Based on Analyses of Mitochondrial Datasets

Guo-Hua Liu; Robin B. Gasser; Ang Su dkk.

PLoS Neglected Tropical Diseases, Vol. 6 No. 2 · 2012 · Inggris · PLOS Scopus

The whipworm, Trichuris trichiura, causes trichuriasis in ∼600 million people worldwide, mainly in developing countries. Whipworms also infect other animal hosts, including pigs (T. suis), dogs (T. vulpis) and non-human primates, and cause disease in these hosts, which is similar to trichuriasis of…