4 results for "Reem Daouk"

Genome-wide gene expression analysis of a murine model of prostate cancer progression: Deciphering the roles of IL-6 and p38 MAPK as potential therapeutic targets

Reem Daouk; Hisham F. Bahmad; Eman Saleh et al.

PLOS ONE, Vol. 15 No. 8 · 2020 · English · PLOS Scopus

Background: Prostate cancer (PCa) is the most commonly diagnosed cancer and the second leading cause of cancer-related deaths among adult males globally. The poor prognosis of PCa is largely due to late diagnosis of the disease when it has already progressed to an advanced stage marked by…

Also available at: DOAJ

Genome-Wide and Phenotypic Evaluation of Stem Cell Progenitors Derived From Gprc5a-Deficient Murine Lung Adenocarcinoma With Somatic Kras Mutations

Reem Daouk; Maya Hassane; Hisham F. Bahmad et al.

Frontiers in Oncology, Vol. 9 · 2019 · English · DOAJ Scopus

Lung adenocarcinomas (LUADs) with somatic mutations in the KRAS oncogene comprise the most common molecular subtype of lung cancer in smokers and present with overall dismal prognosis and resistance to most therapies. Our group recently demonstrated that tobacco carcinogen-exposed mice with…

Modeling Adipogenesis: Current and Future Perspective

Hisham F. Bahmad; Reem Daouk; Joseph Azar et al.

Cells, Vol. 9 No. 10 · 2020 · English · DOAJ Scopus

Adipose tissue is contemplated as a dynamic organ that plays key roles in the human body. Adipogenesis is the process by which adipocytes develop from adipose-derived stem cells to form the adipose tissue. Adipose-derived stem cells’ differentiation serves well beyond the simple goal of producing…