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Frontiers in Oncology
Scopus
ISSN 2234-943X · Frontiers Media S.A. · 38,836 articles in the index
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Journal Article
Deceptive initial presentation of systemic DLBCL with CNS progression following Oligometabolic PET/CT: case report
We present a diagnostically challenging case of a 51-year-old woman with systemic diffuse large B-cell lymphoma (DLBCL) that progressed to secondary central nervous system (CNS) involvement. The initial presentation was notable for a whole-body PET/CT scan showing only subtle, diffuse…
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Journal Article
Association between map-like redness and the risk of gastric cancer and high-risk precancerous lesions: a systematic review and meta-analysis
Background and aimsThe risk of gastric cancer (GC) following Helicobacter pylori (HP) eradication has gained increasing attention. Map-like redness (MLR) is an easily recognizable and highly specific endoscopic feature observed after eradication. We aimed to quantify the association between MLR and…
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Journal Article
Hepatic carcinosarcoma: a rare and aggressive case with unusual molecular signature!
BackgroundPrimary hepatic carcinosarcoma is a rare, aggressive tumour with both carcinomatous and sarcomatous components. Limited documented cases hinder comprehensive understanding, making diagnosis, treatment, and management particularly challenging for clinicians.CaseA 62-year-old female, with…
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Journal Article
Role of Intermediate dose escalation of radiotherapy in the survival of unresectable stage III non-small cell lung cancer patients in the era of immunotherapy
BackgroundThe role of dose escalation of radiotherapy (RT) in unresectable stage III NSCLC followed by immunotherapy is unclear. The objective of the current study is to investigate if intermediate dose escalation (IDE) is beneficial in stage III NSCLC patients who receive definitive concurrent…
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Journal Article
Heterogeneity in benefit finding among breast cancer patients: a latent profile analysis and influencing factors
ObjectivesThis study investigates factors influencing benefit finding among breast cancer patients based on social cognitive theory and develops a nomogram to predict the probability of low benefit finding in breast cancer patients.MethodsA study of 666 breast cancer patients in northern Anhui…
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Journal Article
Case Report: Novel molecular characterization of rare primary mucinous adenocarcinoma of the renal pelvis
Mucinous adenocarcinoma of the renal pelvis (MAC-RP) is an exceedingly rare condition, accounting for less than 1% of malignancies originating from this epithelial site. We report a case of MAC-RP in a woman presenting with right flank pain from obstructing stones, recurrent urinary tract…
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Journal Article
Case Report: Looks can deceive: acute postoperative progressive renal dysfunction and hyperkalemia without significant hydronephrosis
IntroductionHydronephrosis is typically considered a hallmark radiographic finding of urinary tract obstruction, expected to develop within 7 days of onset. However, this timeline may not apply universally. We report a rare case of delayed-onset hydronephrosis in the context of borderline end-stage…
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Journal Article
Clinical characteristics, treatment patterns, and survival in mantle cell lymphoma: a real-world cohort
IntroductionMantle cell lymphoma is a rare, typically aggressive B-cell non-Hodgkin lymphoma that often presents at an advanced stage and carries substantial long-term mortality despite therapeutic advances. Multiple clinical, biological, and treatment-related factors may influence survival in…
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Journal Article
Thyroid and breast carcinomas in a patient with Pendred syndrome: a case report and literature review
BackgroundGoiter in the course of Pendred syndrome may in rare cases be associated with thyroid cancer (about 1% of all Pendred syndrome patients). The coexistence of Pendred syndrome with both thyroid and breast cancer is an even rarer condition reported in only one case.Case presentationWe report…
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Journal Article
Research on potential biomarkers of prostate cancer in Latin America and the Caribbean: a scoping review
BackgroundLatin America and the Caribbean (LAC) have higher prostate cancer (PCa) mortality rates than other regions, possibly due to disparities in detection and treatment, as well as differences in tumor biology and behavior. This scoping review aimed to identify studies conducted in LAC that…
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Journal Article
Pulsed ultrasound-stimulated microbubbles alter the tumor blood supply to enhance the efficacy of high-intensity focused ultrasound ablation of vascular tumors
ObjectiveTo investigate the therapeutic effect and mechanism of Pulsed ultrasound stimulated microbubbles to form thrombus and enhance the effect of high-intensity focused ultrasound (HIFU) for ablation of vascular tumors.MethodsAfter EOMA cells were inoculated subcutaneously in mice to form a…
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Journal Article
Malnutrition determined by the controlling nutritional status score, prognostic nutritional index and hemoglobin-albumin-lymphocyte-platelet score is associated with prolonged hospital stay in liver cancer patients who underwent interventional treatment
BackgroundThe purpose of this study was to investigate the association between the nutritional status evaluated by the Controlling Nutritional Status (CONUT) score, Prognostic Nutritional Index (PNI) and hemoglobin-albumin-lymphocyte-platelet (HALP) score, and the prolonged hospital stay in liver…
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Journal Article
LPCAT1 as a prognostic biomarker and risk indicator for hepatocellular carcinoma: insights into genes related to lipid metabolism
BackgroundHepatocellular carcinoma (HCC) is a lethal malignancy. Lipid metabolic reprogramming influences therapy response, but its prognostic value is undefined.MethodsFrom TCGA and GEO data, we derived an 8-gene lipid metabolism-related risk score (LMrisk) via LASSO regression. Its associations…
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Journal Article
Case Report: Urinary tract isolation of Cronobacter sakazakii in an oncohaematological patient in Southern Italy
BackgroundCronobacter sakazakii is an emerging Gram-negative opportunistic pathogen, mostly associated with severe neonatal infections. In adults, infections are rare and usually occur in immuno-compromised or elderly patients. Urinary tract infections caused by C. sakazakii in oncological adults…
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Journal Article
The methyltransferase METTL16 in digestive system cancers: functions and mechanisms
N6-methyladenosine (m6A) methylation, the most prevalent mRNA modification, affects RNA transcription, splicing, and stability. Methyltransferase-like 16 (METTL16), a novel m6A methyltransferase, regulates the expression of target mRNAs via m6A-mediated modifications. The methyltransferase domain…
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Journal Article
Early peritumoral edema change improve prediction of pathological complete response in breast cancer: a multiparametric magnetic resonance imaging-based model
ObjectiveTo evaluate the independent and additive predictive value of peritumoral edema for pathological complete response (pCR) following neoadjuvant chemotherapy (NAC) in patients with breast cancer.Materials and methodsBreast cancer patients who underwent NAC between February 2018 and December…
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