4 hasil untuk "Rodrigo Cataldi"
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Artikel Jurnal
Hypochlorite-induced oxidation promotes aggregation and reduces toxicity of amyloid beta 1-42
Exacerbated hypochlorite (OCl−) production is linked to neurodegenerative processes, but there is growing evidence that lower levels of hypochlorite activity are important to protein homeostasis. In this study we characterise the effects of hypochlorite on the aggregation and toxicity of amyloid…
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Artikel Jurnal Teks lengkap
The worldwide costs of dementia in 2019
INTRODUCTION: Dementia is a leading cause of death and disability globally. Estimating total societal costs demonstrates the wide impact of dementia and its main direct and indirect economic components. METHODS: We constructed a global cost model for dementia, presenting costs as cumulated global…
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Artikel Jurnal
A dopamine metabolite stabilizes neurotoxic amyloid-β oligomers
Cataldi et al. investigates the impact of the dopamine derivative DOPAL on the Aβ peptide oligomer formation. They report that DOPAL promotes the formation of stable Aβ oligomers that exert toxicity on neuroblastoma cells by increasing cytosolic calcium levels and generating reactive oxygen…
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Artikel Jurnal
Publisher Correction: A dopamine metabolite stabilizes neurotoxic amyloid-β oligomers
A Correction to this paper has been published: https://doi.org/10.1038/s42003-021-01680-7