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2 hasil untuk "Sam Singleton"

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  1. Artikel Jurnal

    The impact of adverse childhood experiences on DNA methylation age: a systematic review and meta-analysis

    Hannah Russell; Gregor Angus; Sam Singleton dkk.

    Clinical Epigenetics, Vol. 18 No. 1 · 2026 · Inggris · DOAJ Scopus

    Abstract Adverse childhood experiences (ACEs), such as abuse and neglect, are associated with poor health in adulthood. One proposed biological mechanism linking early adversity to health outcomes is epigenetic age acceleration (EAA), a measure of biological aging derived from DNA methylation…

  2. Artikel Jurnal

    Adverse childhood experiences and chronic pain in adults aged 86: findings from the Lothian Birth Cohort 1936

    Dhaneesha N. S. Senaratne; Sam Singleton; Kate Timmins dkk.

    Frontiers in Aging, Vol. 6 · 2025 · Inggris · DOAJ Scopus

    BackgroundChronic pain, a major cause of disability, is prevalent in older people. Exposure to multiple adverse childhood experiences (ACEs) is associated with increased levels of chronic pain in later life. However, this association has not been investigated in people aged older than 80 years…