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  1. Artikel Jurnal

    Autophagy in Parkinson's Disease

    Xu Hou; Jens O. Watzlawik; Fabienne C. Fiesel dkk.

    Journal of Molecular Biology · 2020 · Inggris · OpenAlex Scopus

    Impaired protein homeostasis and accumulation of damaged or abnormally modified protein are common disease mechanisms in many neurodegenerative disorders, including Parkinson's disease (PD). As one of the major degradation pathways, autophagy plays a pivotal role in maintaining effective turnover…

  2. Artikel Jurnal Teks lengkap

    cis-Regulatory Elements in Plant Development, Adaptation, and Evolution

    Alexandre P. Marand; Andrea L. Eveland; Kerstin Kaufmann dkk.

    Annual Review of Plant Biology · 2023 · Inggris · OpenAlex

    cis-Regulatory elements encode the genomic blueprints that ensure the proper spatiotemporal patterning of gene expression necessary for appropriate development and responses to the environment. Accumulating evidence implicates changes to gene expression as a major source of phenotypic novelty in…

  3. Artikel Jurnal Teks lengkap

    Current Challenges and Opportunities in Microstructure-Related Properties of Advanced High-Strength Steels

    Dierk Raabe; Binhan Sun; Alisson Kwiatkowski da Silva dkk.

    Metallurgical and Materials Transactions A · 2020 · Inggris · OpenAlex Scopus

    Abstract This is a viewpoint paper on recent progress in the understanding of the microstructure–property relations of advanced high-strength steels (AHSS). These alloys constitute a class of high-strength, formable steels that are designed mainly as sheet products for the transportation sector…

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  1. Artikel Jurnal Teks lengkap

    Single-cell analysis defines a pancreatic fibroblast lineage that supports anti-tumor immunity

    Colin P. Hutton; Felix Heider; Adrián Blanco‐Gómez dkk.

    Cancer Cell · 2021 · Inggris · OpenAlex Scopus

    Fibroblasts display extensive transcriptional heterogeneity, yet functional annotation and characterization of their heterocellular relationships remains incomplete. Using mass cytometry, we chart the stromal composition of 18 murine tissues and 5 spontaneous tumor models, with an emphasis on…

  2. Artikel Jurnal

    2021 American College of Rheumatology/Vasculitis Foundation Guideline for the Management of Giant Cell Arteritis and Takayasu Arteritis

    Mehrdad Maz; Sharon A. Chung; Andy Abril dkk.

    Arthritis & Rheumatology · 2021 · Inggris · OpenAlex Scopus

    OBJECTIVE: To provide evidence-based recommendations and expert guidance for the management of giant cell arteritis (GCA) and Takayasu arteritis (TAK) as exemplars of large vessel vasculitis. METHODS: Clinical questions regarding diagnostic testing, treatment, and management were developed in the…

  3. Artikel Jurnal Teks lengkap

    2021 American College of Rheumatology/Vasculitis Foundation Guideline for the Management of Antineutrophil Cytoplasmic Antibody–Associated Vasculitis

    Sharon A. Chung; Carol A. Langford; Mehrdad Maz dkk.

    Arthritis & Rheumatology · 2021 · Inggris · OpenAlex Scopus

    OBJECTIVE: To provide evidence-based recommendations and expert guidance for the management of antineutrophil cytoplasmic antibody-associated vasculitis (AAV), including granulomatosis with polyangiitis (GPA), microscopic polyangiitis (MPA), and eosinophilic granulomatosis with polyangiitis (EGPA)…

  4. Artikel Jurnal

    2025 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Association

    Seth Shay Martin; Aaron W. Aday; Norrina B. Allen dkk.

    Circulation · 2025 · Inggris · OpenAlex Scopus

    BACKGROUND: The American Heart Association (AHA), in conjunction with the National Institutes of Health, annually reports the most up-to-date statistics related to heart disease, stroke, and cardiovascular risk factors, including core health behaviors (smoking, physical activity, nutrition, sleep…

  5. Artikel Jurnal Teks lengkap

    A comparative genomics multitool for scientific discovery and conservation

    Diane P. Genereux; Aitor Serres; Joel Armstrong dkk.

    Nature · 2020 · Inggris · OpenAlex Scopus

    The Zoonomia Project is investigating the genomics of shared and specialized traits in eutherian mammals. Here we provide genome assemblies for 131 species, of which all but 9 are previously uncharacterized, and describe a whole-genome alignment of 240 species of considerable phylogenetic…

  6. Artikel Jurnal Teks lengkap

    Multiplexed CRISPR-based microfluidic platform for clinical testing of respiratory viruses and identification of SARS-CoV-2 variants

    Nicole L. Welch; Meilin Zhu; Catherine Hua dkk.

    Nature Medicine · 2022 · Inggris · OpenAlex Scopus

    The coronavirus disease 2019 (COVID-19) pandemic has demonstrated a clear need for high-throughput, multiplexed and sensitive assays for detecting severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and other respiratory viruses and their emerging variants. Here, we present a…