9 results for "Stephan Windecker"

Amplatzer Amulet Left Atrial Appendage Occluder Versus Watchman Device for Stroke Prophylaxis (Amulet IDE): A Randomized, Controlled Trial

Dhanunjaya Lakkireddy; David Thaler; Christopher R. Ellis et al.

Circulation · 2021 · English · OpenAlex Scopus

Background: Percutaneous closure of the left atrial appendage (LAA) is an alternative to chronic oral anticoagulation to reduce stroke risk in patients with nonvalvular atrial fibrillation. The Amulet IDE trial (Amplatzer Amulet Left Atrial Appendage Occluder IDE Trial) was designed to evaluate the…

Effect of Evolocumab on Coronary Plaque Phenotype and Burden in Statin-Treated Patients Following Myocardial Infarction

Stephen James Nicholls; Yu Kataoka; Steven E. Nissen et al.

JACC. Cardiovascular imaging · 2022 · English · OpenAlex Scopus

Dual Antiplatelet Therapy after PCI in Patients at High Bleeding Risk

Marco Valgimigli; Enrico Frigoli; Dik Heg et al.

New England Journal of Medicine · 2021 · English · OpenAlex Scopus

BACKGROUND: The appropriate duration of dual antiplatelet therapy in patients at high risk for bleeding after the implantation of a drug-eluting coronary stent remains unclear. METHODS: One month after they had undergone implantation of a biodegradable-polymer sirolimus-eluting coronary stent, we…

Polymer-based or Polymer-free Stents in Patients at High Bleeding Risk

Stephan Windecker; Azeem Latib; Elvin Kedhi et al.

New England Journal of Medicine · 2020 · English · OpenAlex Scopus

BACKGROUND: Polymer-free drug-coated stents provide superior clinical outcomes to bare-metal stents in patients at high bleeding risk who undergo percutaneous coronary intervention (PCI) and are treated with 1 month of dual antiplatelet therapy. Data on the use of polymer-based drug-eluting stents…

Obesity and cardiovascular disease: an ESC clinical consensus statement

Konstantinos C. Koskinas; Emeline M. Van Craenenbroeck; Charalambos A. Antoniades et al.

European Heart Journal · 2024 · English · OpenAlex Scopus

The global prevalence of obesity has more than doubled over the past four decades, currently affecting more than a billion individuals. Beyond its recognition as a high-risk condition that is causally linked to many chronic illnesses, obesity has been declared a disease per se that results in…

Bicuspid Aortic Valve Morphology and Outcomes After Transcatheter Aortic Valve Replacement

Sung‐Han Yoon; Won‐Keun Kim; Abhijeet Dhoble et al.

Journal of the American College of Cardiology · 2020 · English · OpenAlex Scopus

Right Ventricular-Pulmonary Arterial Coupling and Afterload Reserve in Patients Undergoing Transcatheter Tricuspid Valve Repair

Michael I. Brener; Philipp C. Lurz; Jörg Hausleiter et al.

Journal of the American College of Cardiology · 2022 · English · OpenAlex Scopus

Effect of Alirocumab Added to High-Intensity Statin Therapy on Coronary Atherosclerosis in Patients With Acute Myocardial Infarction

Lorenz Räber; Yasushi Ueki; Tatsuhiko Otsuka et al.

JAMA · 2022 · English · OpenAlex

Importance: Coronary plaques that are prone to rupture and cause adverse cardiac events are characterized by large plaque burden, large lipid content, and thin fibrous caps. Statins can halt the progression of coronary atherosclerosis; however, the effect of the proprotein convertase subtilisin…

Transfemoral tricuspid valve replacement and one-year outcomes: the TRISCEND study

Susheel Kodali; Rebecca Tung Hahn; Raj Makkar et al.

European Heart Journal · 2023 · English · OpenAlex Scopus

BACKGROUND AND AIMS: For patients with symptomatic, severe tricuspid regurgitation (TR), early results of transcatheter tricuspid valve (TV) intervention studies have shown significant improvements in functional status and quality of life associated with right-heart reverse remodelling. Longer-term…