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5 hasil untuk "Steve Rodriguez"

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  1. Artikel Jurnal

    Dataset of breast thermography images for the detection of benign and malignant masses

    Steve Rodriguez-Guerrero; Humberto Loaiza-Correa; Andrés-David Restrepo-Girón dkk.

    Data in Brief, Vol. 54 · 2024 · Inggris · DOAJ Scopus

    Thermographic image analysis is a subfield of diagnostic image processing aimed at detecting breast abnormalities in women at an early stage. It is a developing field of research and its effectiveness and scope require scientific assessment to be determined. An open-access dataset has been created…

  2. Artikel Jurnal Teks lengkap

    Machine learning identifies candidates for drug repurposing in Alzheimer’s disease

    Steve Rodriguez; Clemens B. Hug; Petar V. Todorov dkk.

    Nature Communications · 2021 · Inggris · OpenAlex Scopus

    Clinical trials of novel therapeutics for Alzheimer's Disease (AD) have consumed a large amount of time and resources with largely negative results. Repurposing drugs already approved by the Food and Drug Administration (FDA) for another indication is a more rapid and less expensive option. We…

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  3. Artikel Jurnal

    Causal inference in medical records and complementary systems pharmacology for metformin drug repurposing towards dementia

    Marie-Laure Charpignon; Bella Vakulenko-Lagun; Bang Zheng dkk.

    Nature Communications, Vol. 13 No. 1 · 2022 · Inggris · DOAJ Scopus

    Previous observational studies of the diabetes drugs metformin vs. sulfonylureas have yielded mixed results about whether metformin reduces the risk of dementia, relative to the sulfonylureas. Here, the authors apply a novel competing risks approach to emulate dementia-related target trials in…

  4. Artikel Jurnal

    TYK2 mediates neuroinflammation in Alzheimer’s disease brains with TDP-43 pathology

    Laura E. König; Steve Rodriguez; Clemens Hug dkk.

    Nature Communications, Vol. 17 No. 1 · 2026 · Inggris · DOAJ Scopus

    Abstract Neuroinflammation is a pathological feature of neurodegenerative diseases like Alzheimer’s disease and ALS. Cytoplasmic dsRNA (cdsRNA) triggers a type-I interferon response in human neural cells, leading to their death, and is found in neurons of C9ORF72-ALS patients. Here, we report the…