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Nature Communications
Scopus
ISSN 2041-1723 · Nature Portfolio · 84.859 artikel di indeks
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Artikel Jurnal
Roll-to-Roll AgNWs Networks/Ag Finger by Self-Masking Protection for Large-Area Monolithic Flexible Organic Solar Cells
Abstract Flexible large-area monolithic organic solar cells suffer from electrical loss during up-scaling due to the limited conductivity of transparent electrodes. In this work, highly conductive silver grid fingers are integrated onto a roll-to-roll gravure-printed silver nanowire electrode via…
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Artikel Jurnal
Influence of protein aggregates, extracellular vesicles, and lipoprotein fusion on ionizable lipid nanoparticles protein corona analysis
Abstract Since 2018, ionizable lipid nanoparticles (LNPs) have revolutionized nucleic acid therapeutics. However, achieving potent extrahepatic delivery remains a formidable challenge, primarily due to rapid hepatic uptake driven by apolipoprotein adsorption. While analyzing the LNP protein corona…
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Toward traceable global systems for end-of-life photovoltaic waste
Rapid global expansion of photovoltaics is driving degraded module flows to emerging markets. This flow occurs amid limited regulatory oversight and recycling capacity, posing substantial environmental risks to importing regions. Mitigating these risks necessitates cross-border governance and…
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Governing black soils for food and climate security
Black soils feed the world yet remain undervalued in food and climate governance frameworks. A policy package, including global monitoring as public infrastructure, co-designed and place-based solutions based on tailored tools, planning that fits land and people, mobilizing alliance with finance…
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Artikel Jurnal
A macrophage-induced subpopulation of mesenchymal cells expressing Fcer1g contributes to wound-induced fibrosis
Abstract Fibrosis commonly occurs during adult skin wound healing, characterized by excessive extracellular matrix (ECM), leading to scarring. Mesenchymal cells, the primary ECM-producing population, are heterogeneous with varying fibrotic propensity during healing. While pro-fibrotic embryonically…
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Artikel Jurnal
BRAHMA represses STOP1-NRT1.1 module to control plant rhizosphere alkalization and acid stress adaptation
Abstract Covering 40–50% of world’s arable lands, acidic soils pose a major constraint on global crop productivity by severely restricting root development and nutrient acquisition. The Arabidopsis C2H2-type transcription factor STOP1 plays a fundamental role in mitigating acid stress by activating…
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Male obesity causes adipose mitochondrial dysfunction in F1 mouse progeny via a let-7-DICER axis
Abstract Male obesity negative affects gametic function and offspring metabolism. We here describe that (F0) obesity and weight loss in male mice reversibly alter metabolism and impair adipose mitochondrial function. These metabolic aberrations are transmitted to male offsprings (F1), which display…
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Axially engineered single atoms in enzyme-mimic-binding pocket steering dehalogenation–polymerization pathways toward water pollutant upcycling
Abstract Polymerization-based advanced oxidation processes (P-AOPs) represent a promising strategy for simultaneous pollutant abatement and water resource recovery. However, selective removal of halogenated organic pollutants via P-AOP remains challenging due to uncontrollable oligomerization…
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Reconstitution of spermatogenesis and continuous generation of functional haploid germ cells in mouse testicular organoids
Abstract Testicular organoids that support spermatogenesis and generate functional haploid germ cells are still lacking. Here, we developed a formation-differentiation culture approach to generate optimized testicular organoids (O-Torgs) derived from neonatal mouse primary testicular cells. These…
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Artikel Jurnal
Nanoscale exchange-bias magnetic tunnel junctions enabled memristive synapse and leaky-integrate-fire neuron for neuromorphic computing
Abstract Neuromorphic computing implemented by spintronic memories offers computational advantages, including in-memory computing capability, high energy efficiency, and near-unlimited endurance. However, their basic units, magnetic tunnel junctions (MTJs), face inherent challenges in emulating…
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Artikel Jurnal
Cholesterol-lowering effects of oats induced by microbially produced phenolic metabolites in metabolic syndrome: a randomized controlled trial
Abstract Oats have various positive effects on human health, but the underlying mechanisms are not fully understood. To identify oat-microbiome-host interactions contributing to metabolic improvements, we conducted two randomized controlled dietary interventions in parallel-design in individuals…
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Distributed multitudes of bio-inspired, biodegradable Lagrangian sensors for environmental sustainability
Bioresorbable distributed Lagrangian sensors may enable environmentally sustainable spatio-temporal mapping of acute disasters through integrated dynamic and chemical sensing. We summarize recent work in bioinspired, ultraminiature structures, sensing targets, wireless communication and power…
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RAS/MEK/PI3K pathway inhibition augments response to CD40 agonism by targeting CD11b+ Bregs thereby overcoming melanoma PD1-resistance
Abstract Development of effective second-line treatment options for patients with BRAF wt NRAS wt or BRAF wt NRAS mut melanoma resistant to immune checkpoint blockade (ICB) is crucial. While systemic delivery of agonist CD40 (aCD40) plus anti-PD1 (αPD1) showed activity in patients with…
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Casein kinase 1a mediates a two-step subunit remodeling mechanism to regulate the FRQ-FRH circadian clock complex
Abstract The circadian clock of Neurospora operates through a negative feedback loop in which FREQUENCY (FRQ), along with FRQ-interacting RNA helicase (FRH) and casein kinase 1a (CK1a), inhibits its transcriptional activator, WHITE COLLAR COMPLEX (WCC), via phosphorylation. CK1a, anchored to FRQ…
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Artikel Jurnal
Intelectin-2 is a broad-spectrum antimicrobial lectin
Abstract Mammals regulate the localization, composition, and activity of their native microbiota at colonization sites. Lectins residing at these sites influence microbial populations, but their functional roles are often unclear. Intelectins are found in chordates at mucosal barriers, but their…
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Changes in phenology mediate vertebrate population responses to temperature globally
Abstract Phenotypic responses to climate affect individual fitness, but the extent to which this translates into effects on population dynamics remains poorly understood. We assemble 213 time series on phenotypes and population sizes of wild vertebrates globally and match them with local climate…
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Artikel Jurnal
Insights into the operational stability of wide-bandgap perovskite and tandem solar cells under rapid thermal cycling
Abstract Temperature variations can induce phase transformations and strain in perovskite solar cells (PSCs), undermining their structural stability and device performance. Despite growing interest, the operational stability of triple-cation wide-bandgap (WBG) PSCs and tandem solar cells (TSCs)…
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Efficient and stable catalytic hydrolysis of perfluorocarbon enabled by SO2-mediated proton supply
Abstract Catalytic hydrolysis is an effective strategy for decomposing tetrafluoromethane (CF4), one of the most chemically inert per- and polyfluoroalkyl substances (PFAS). A key challenge in this process lies in enhancing proton availability to facilitate efficient and stable C–F bond activation…
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Artikel Jurnal
Structural basis for the subtype-selectivity of KCa2.2 channel activators
Abstract Small-conductance (KCa2.2) and intermediate-conductance (KCa3.1) Ca2+-activated K+ channels are gated by a Ca2+-calmodulin dependent mechanism. NS309 potentiates the activity of both KCa2.2 and KCa3.1, while rimtuzalcap selectively activates KCa2.2. Rimtuzalcap has been used in clinical…
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Artikel Jurnal
Structural basis of outer membrane biogenesis by the TamAB translocase
Abstract The outer membrane is vital for Gram-negative bacteria, playing crucial roles in colonization, pathogenesis and drug resistance. The translocation and assembly module A and B (TamAB) nanomachinery has been reported to be involved in transport of phospholipids from the inner membrane to the…
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