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An atlas of substrate specificities for the human serine/threonine kinome

Jared Lee Johnson; Tomer M. Yaron; Emily M. Huntsman dkk.

Nature · 2023 · Inggris · OpenAlex Scopus

Abstract Protein phosphorylation is one of the most widespread post-translational modifications in biology 1,2 . With advances in mass-spectrometry-based phosphoproteomics, 90,000 sites of serine and threonine phosphorylation have so far been identified, and several thousand have been associated…