6 hasil untuk "Xiang-Rong Qin"
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Artikel Jurnal Teks lengkap
The non-structural protein of SFTSV activates NLRP1 and CARD8 inflammasome through disrupting the DPP9-mediated ternary complex
Inflammasomes function as immune-signaling platforms that were assembled following detection of pathogens. NLRP1 and CARD8 are related inflammasomes that use their C-terminal (CT) fragments containing a caspase recruitment domain (CARD) and the UPA domain to initiate the inflammasome. At rest…
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Artikel Jurnal Teks lengkap
Severe fever with thrombocytopenia syndrome can masquerade as hemorrhagic fever with renal syndrome
Background: Severe fever with thrombocytopenia syndrome (SFTS) is an emerging viral hemorrhagic fever with a high fatality rate and high frequency of person-to-person transmission and is caused by SFTSV, a tick-borne Phlebovirus. Because SFTS has similar clinical manifestations and epidemic…
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Artikel Jurnal Teks lengkap
Novel Bartonella Species in Insectivorous Bats, Northern China
Bartonella species are emerging human pathogens. Bats are known to carry diverse Bartonella species, some of which are capable of infecting humans. However, as the second largest mammalian group by a number of species, the role of bats as the reservoirs of Bartonella species is not fully explored…
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Artikel Jurnal Teks lengkap
Pathogenic Rickettsia , Anaplasma , and Ehrlichia in Rhipicephalus microplus ticks collected from cattle and laboratory hatched tick larvae
Background: The order Rickettsiales contains a group of vector-borne gram-negative obligate intracellular bacteria, which often cause human emerging infectious diseases and economic losses for dairy and meat industries. The purpose of this study is to investigate the distribution of the pathogens…
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Artikel Jurnal Teks lengkap
Emergence of Zika virus infection in China
Currently, Zika virus (ZIKV) is spreading across the world and no ZIKV infection cases have ever been reported in China. Here, we aimed to determine whether ZIKV infection exists in China. Blood samples of 273 healthy individuals were collected from Nanning City, Guangxi Province, China in March…
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Artikel Jurnal Teks lengkap
Pair combinations of human monoclonal antibodies fully protected mice against bunyavirus SFTSV lethal challenge
Severe fever with thrombocytopenia syndrome (SFTS) is a viral hemorrhagic fever caused by a tick-borne virus SFTSV with a mortality rate of up to 30%. Currently, there is no vaccine or effective therapy for SFTS. Neutralizing monoclonal antibody therapy, which provides immediate passive immunity…