10 hasil untuk "Yair Alvarez-Ricardo"

New Coordination Polymers with Unexpected Octahedral copper(II) Geometry: Synthesis, Supramolecular and Theoretical Study

Yair Alvarez-Ricardo; Nicolás Puentes-Díaz; Mario A. Macías dkk.

ACS Omega, Vol. 11 No. 20 · 2026 · Inggris · DOAJ Scopus

High Yield Synthesis of Curcumin and Symmetric Curcuminoids: A “Click” and “Unclick” Chemistry Approach

Marco A. Obregón-Mendoza; William Meza-Morales; Yair Alvarez-Ricardo dkk.

Molecules, Vol. 28 No. 1 · 2022 · Inggris · DOAJ Scopus

The worldwide known and employed spice of Asian origin, turmeric, receives significant attention due to its numerous purported medicinal properties. Herein, we report an optimized synthesis of curcumin and symmetric curcuminoids of aromatic (bisdemethoxycurcumin) and heterocyclic type, with yields…

Expected and Unexpected Products in Half Curcuminoid Synthesis: Crystal Structures of But-3-en-2-ones and 3-Methylcyclohex-2-enones

Marco A. Obregón-Mendoza; Imilla I. Arias-Olguín; William Meza-Morales dkk.

Crystals, Vol. 11 No. 4 · 2021 · Inggris · DOAJ Scopus

The expected (E)-but-3-en-2-ones compounds I and II (half curcuminoids) were obtained by the Claisen–Schmidt reaction between aldehydes 3,4-dimethoxybenzaldehyde or 4-nitrobenzaldehyde with acetone. Concomitantly, 3-methylcyclohex-2-enones compounds III and IV arose from an unexpected reaction of…

Synthesis, Characterization, and Anticancer Activity of Vanadium (III) Complexes With Pyridyl–Triazole Ligands

Yair Alvarez-Ricardo; Deissy N. Jaramillo; Adrian Leonardo Orjuela dkk.

Bioinorganic Chemistry and Applications, Vol. 2026 · 2026 · Inggris · DOAJ Scopus

Three new V (III) complexes with triazole ligands were obtained and fully characterized using regular analytical techniques, including the unequivocal determination of the structure of complex VL3D by single-crystal x-ray diffraction analysis. The formation of VL3D involves an oxidation process…

A New Family of Homoleptic Copper Complexes of Curcuminoids: Synthesis, Characterization and Biological Properties

William Meza-Morales; Juan C. Machado-Rodriguez; Yair Alvarez-Ricardo dkk.

Molecules, Vol. 24 No. 5 · 2019 · Inggris · DOAJ Scopus

We report herein the synthesis and crystal structures of five new homoleptic copper complexes of curcuminoids. The scarcity of reports of homoleptic complex structures of curcuminoids is attributed to the lack of crystallinity of such derivatives, and therefore, their characterization by single…

Non-Cytotoxic Dibenzyl and Difluoroborate Curcuminoid Fluorophores Allow Visualization of Nucleus or Cytoplasm in Bioimaging

Marco A. Obregón-Mendoza; Imilla I. Arias-Olguín; M. Mirian Estévez-Carmona dkk.

Molecules, Vol. 25 No. 14 · 2020 · Inggris · DOAJ Scopus

Curcumin, the most important secondary metabolite isolated from Curcuma longa, is known for its numerous purported therapeutic properties and as a natural dye. Herein, based on curcumin’s intrinsic fluorescence, a search for improved curcumin-based fluorophores was conducted. Within the set of…

In Vivo Evaluation of a Nanoemulsion-Delivered Chromium(III)–Triazole Complex Against Fluconazole-Resistant Candida albicans

Maria Valentina Bedoya-Florez; Ricardo A. Murcia-Galán; Martha Viviana Roa-Cordero dkk.

Journal of Fungi, Vol. 12 No. 6 · 2026 · Inggris · DOAJ Scopus

Candida albicans remains one of the leading causes of invasive fungal infections and is recognized as a critical-priority pathogen by the World Health Organization. The increasing emergence of resistance to azole antifungals such as fluconazole highlights the need for alternative therapeutic…

Homoleptic Complexes of Heterocyclic Curcuminoids with Mg(II) and Cu(II): First Conformationally Heteroleptic Case, Crystal Structures, and Biological Properties

William Meza-Morales; Yuritzi Alejo-Osorio; Yair Alvarez-Ricardo dkk.

Molecules, Vol. 28 No. 3 · 2023 · Inggris · DOAJ Scopus

We report herein the synthesis and characterization of three heterocyclic curcuminoid ligands and their homoleptic metal complexes with magnesium and copper. Thus, N-methyl-2-pyrrolecarboxaldehyde, Furan-2-carboxaldehyde, and 2-Thiophenecarboxaldehyde were condensed with 2,4-pentanedione-boron…

Full Structural Characterization of Homoleptic Complexes of Diacetylcurcumin with Mg, Zn, Cu, and Mn: Cisplatin-level Cytotoxicity in Vitro with Minimal Acute Toxicity in Vivo

William Meza-Morales; M. Mirian Estévez-Carmona; Yair Alvarez-Ricardo dkk.

Molecules, Vol. 24 No. 8 · 2019 · Inggris · DOAJ Scopus

At the present time, scientists place a great deal of effort worldwide trying to improve the therapeutic potential of metal complexes of curcumin and curcuminoids. Herein, the synthesis of four homoleptic metal complexes with diacetylcurcumin (DAC), using a ligand designed to prevent the…

Spontaneous Enantiomeric Resolution of 1,3-Diols from the Naphtylidene Derivative of 2,4-Pentanedione

Yair Alvarez-Ricardo; Dylan Sánchez-López; William Meza-Morales dkk.

Molbank, Vol. 2022 No. 4 · 2022 · Inggris · DOAJ Scopus

Enantiomers (2S, 4S)- and (2R, 4R)-3-(naphthalene-1-ylmethyl) pentane-2,4-diols were synthesized by the reduction of (Z)-4-hydroxy-3-(naphthalene-1-ylmethyl) pent-3-en-2-one with NaBH4 in methanol (MeOH). Crystallization in dichloromethane of this racemic mixture led to simple crystals with a…