2 results for "Victor Bessonneau-Gaborit"
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Journal Article
Expression profile of CASSIOPEIA patients refines prognostic value of MRD negativity in multiple myeloma
Abstract Long-term follow-up of the CASSIOPEIA trial (NCT02541383) demonstrated superior progression-free survival (PFS) with daratumumab, both in combination with bortezomib, thalidomide, and dexamethasone during induction and consolidation, and during maintenance therapy, in transplant-eligible…
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Journal Article
Exploring the impact of dexamethasone on gene regulation in myeloma cells
The study uncovers epigenomic changes associated with dexamethasone response heterogeneity in myeloma cells, revealing rewired promoter–enhancer interactions and DNA loop stabilization. Among glucocorticoids (GCs), dexamethasone (Dex) is widely used in treatment of multiple myelomas. However…