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The dynamics of asymptomatic Plasmodium spp. infections following 10 years of malaria control interventions in Northern Sahelian Ghana
Current interventions targeting malaria control in sub-Saharan Africa (SSA) are focused on Plasmodium falciparum, the most prevalent species infecting humans. Despite renewed efforts for malaria elimination in SSA, little attention has been paid to the neglected parasites P. malariae, P. ovale…
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Recurrent episodes of pneumonia are associated with worse lung function in people with HIV
Background: HIV is associated with a decreased diffusing capacity for carbon monoxide (DLco), decreased spirometry, and an increased risk for developing obstructive lung disease, even in never-smokers. Pneumonia is a risk factor for impaired pulmonary function in people with HIV (PWH), but whether…
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Discovery of a Roman Quarry for Pozzolanic aggregates in the Euganean Hills Magmatic District, Northeast Italy: A stepwise archaeometric approach
This study investigates the provenance of volcanic aggregates used in Roman lime-based mortars from the theatre–bath complex at Via Scavi in Montegrotto Terme (ancient Fons Aponi, northeastern Italy), dated to the Early Imperial period. An integrated stepwise archaeometric approach combining…
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Psychometric properties of the Chinese version of the Athletic Identity Measurement Scale Plus: A confirmatory study on Chinese adolescents
Background: Athletic identity plays a crucial role in athletes’ psychological well-being and performance. Although the Athletic Identity Measurement Scale Plus (AIMSP) effectively assesses this construct in Western contexts, its application in diverse cultural settings remains challenging. This…
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Genome-wide bioinformatics analysis of the MATE gene family for abiotic stress tolerance in sunflower ( Helianthus annuus L.)
Abiotic stressors, such as drought, salinity, and heavy metals, induce physiological changes, nutritional imbalances, molecular alterations, and oxidative stress in plants, which significantly reduce productivity. However, the secondary transporters, multidrug and toxic compound extrusion (MATE)…
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Time to sputum culture conversion, treatment outcomes, and associated factors among rifampicin-resistant or multidrug-resistant tuberculosis patients in the Sidama region, Ethiopia: A retrospective follow-up study
Background: Time to sputum culture conversion is critical for follow-up treatment effectiveness in multidrug-resistant tuberculosis patients. However, the evidence regarding time to culture conversion, treatment outcomes, and the associated factors was sparse and inconsistent. Objective: This study…
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Exploring the association between serum vitamins and CAP-defined hepatic steatosis in lean and non-lean adults with NAFLD: A cross-sectional study
Background: Non-alcoholic fatty liver disease (NAFLD) is highly prevalent worldwide, yet the role of serum vitamins in hepatic fat accumulation, particularly across lean and non-lean individuals, remains incompletely understood. This study evaluated associations between serum levels of vitamins A…
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A food-grade cell dissociation agent via regulatory pre-check framework
Advancements in cell-based foods require materials that meet the highest food safety standards. Conventional cell dissociation agents, such as animal-derived trypsin, pose significant risks including viral contamination and allergenicity, which hinder their use in food production. To overcome this…
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Multi-task adaptive deep sparse canonical correlation analysis for multi-omics cancer survival prediction
Integrating high-dimensional multi-omics data is essential for uncovering the coordinated molecular mechanisms underlying cancer progression and improving survival prediction. DNA methylation and mRNA expression represent two tightly coupled regulatory layers; however, many existing approaches…
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Point-of-care brain magnetic resonance imaging in children with head trauma (BRAINCHILD): Protocol for a prospective observational cohort study
Background: Traumatic brain injury (TBI) is a leading cause of disability and death in children. More than 30% of children presenting to the emergency department (ED) with head trauma undergo brain computed tomography (CT), the standard neuroimaging modality in acute evaluation of intracranial…
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Research on fire scenario analysis and emergency response strategies for L-shaped buildings using FDS
With the rapid development of information and communication technologies, modern fire rescue models are evolving towards informatization, proactivity, and spatialization. Existing fire simulation models primarily focus on the impact of individual building parameters, lacking a systematic analysis…
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Adverse events in different administration routes of Edaravone: A pharmacovigilance study based on the FDA adverse event reporting system
The U.S. Food and Drug Administration (FDA) approved intravenous edaravone for the treatment of amyotrophic lateral sclerosis (ALS) in 2017, followed by the approval of the oral formulation in 2022. This study aims to utilize the FDA#39;s Adverse Event Reporting System (FAERS) to investigate the…
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The response of small boreal catchments to extreme weather event: Hurricane Larry
The boreal environment is high in dissolved organic carbon (DOC) and iron concentrations. This DOC is enriched in functional groups allowing it to bind strongly with iron and act as a significant source of iron to the coastal and marine environment. As climate change intensifies more extreme…
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Effect of intravenous vitamin C administration on chemotherapy-induced adverse events in patients with nasopharyngeal cancer
Nasopharyngeal carcinoma is prevalent in Thailand, with a substantial proportion of cases diagnosed at advanced stages. The standard treatment, concurrent chemoradiotherapy, is associated with considerable adverse effects, which may compromise therapeutic efficacy and diminish patients’ quality of…
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Virologic suppression among HIV-positive pregnant and lactating women receiving antiretroviral therapy in Africa: A systematic review and meta-analysis
Background: The elimination of mother-to-child transmission of human immunodeficiency virus (HIV) is a key global public health priority. In Africa, virologic failure among people living with HIV continues to pose a significant public health challenge, affecting both individual well-being and…
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Barriers and facilitators to condom use among People Who Inject Drugs in Georgia: A qualitative study guided by the COM-B model
People who inject drugs (PWID) are at a heightened risk of contracting and transmitting HIV due to shared needles and unsafe sexual practices. Evidence on what shapes condom use among PWID in Georgia is limited. We conducted qualitative study among PWID recruited from two harm-reduction…
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Epidemiological review on the resurgence of measles outbreaks in Canada during the post-elimination era: A scoping review
In 1998, the World Health Organization declared that measles had been eliminated in Canada. Despite this status, Canada continues to experience sporadic outbreaks driven by importations from endemic countries. Understanding the post-elimination outbreaks is crucial for informing prevention and…
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Knowledge, acceptability, and attitudes regarding minimally invasive tissue sampling (MITS) techniques in Brazil
Determining cause of death is fundamental for health services to guide the formulation of appropriate public policies to reduce and prevent mortality. In Brazil, some deaths still do not have their underlying cause defined, and in these cases, performing a complete diagnostic autopsy (CDA) is…
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