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Journal of the Pakistan Medical Association
Scopus
ISSN 0030-9982 · Pakistan Medical Association · 1.838 artikel di indeks
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Artikel Jurnal
Seizures with abdominal pain—a case of porphyrias complicated with status epilepticus
Acute intermittent porphyria (AIP) is the most common type of porphyria, caused due to the deficiency of HMBS enzyme in the heme synthesis pathway. One of its infrequent and clinically challenging complications is status epilepticus. We present the case of a 14-year-old boy, who was previously…
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Artikel Jurnal
Paediatric Cerebral Sinovenous Thrombosis: Diagnostic challenges, therapeutic uncertainties, and context-sensitive management opportunities
Cerebral sinovenous thrombosis (CSVT) constitutes a relatively smaller, but clinically significant and disproportionately morbid cause of childhood cerebrovascular disease. The annual incidence of cerebral sinovenous thrombosis in children (term neonates through 18 years) ranges between 0.4 and 0.7…
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Artikel Jurnal
Quality of life before & after genitourinary fistula repair - Insights from WHOQOL-BREF
Objective: To compare preoperative and postoperative quality of life in women undergoing genitourinary fistula repair. Method: The quasi-experimental study was conducted at the Department of Urology, Sindh Institute of Urology and Transplantation, Karachi, from January to December 2023, and…
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Artikel Jurnal
Exploring the pubertal challenges of female adolescents with blindness
Objective: To explore the unique pubertal challenges and the experiences faced by female adolescents with blindness. Method: The qualitative study was conducted from October 2023 to August 2024 at the Department of Psychology, University of Central Punjab, Lahore, Pakistan, and comprised female…
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Artikel Jurnal
Retrospective study of correction of rigid adult clubfoot or equinovarus deformity using Ilizarov technique, outcomes in Pakistan
Abstract Objectives: To assess the outcomes of correction of adult equinovarus clubfoot with Ilizarov technique. Method: The retrospective study was conducted from December 2023 to January 2025 at the Department of Orthopaedic Surgery, Liaquat National Hospital and Medical College, Karachi, and…
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Artikel Jurnal
Genetic Profiling of GADD45A (1506T>C) Single Nucleotide Polymorphism rs3783469 in Breast Cancer Development
Objective: To assess the association between the growth arrest and deoxyribonucleic acid damage 45 alpha (1506 thymine > cytosine) polymorphism (reference single nucleotide polymorphism cluster ID 3783469) and breast cancer development in Pakistani females. Method: The case-control study was…
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Artikel Jurnal
Dual diuretic therapy for hypertension in advanced chronic kidney disease
Hypertension affects approximately 85% of individuals with advanced chronic kidney disease (glomerular filtration rate < 30 ml/min), primarily due to increased volume load[1]. At this stage, kidneys lose their ability to achieve the desired fractional excretion for sodium (FeNa), thus predisposing…
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Artikel Jurnal
Predictors of glycaemic control in children and adolescents with type 1 diabetes mellitus
Objective: To identify the predictors of glycaemic control in children and adolescents with type-1 diabetes mellitus. Method: The analytical, cross-sectional study was conducted at the Paediatric Endocrinology Department of the National Institute of Child Health, Karachi, from June to November…
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Artikel Jurnal
Deciphering the impact of pet or balloon play as a stress buster for exam-stressed students
Objectives: To explore if exam stress affects students by altering their heart rate and blood pressure, and if it varies with age and gender. Method: The cross-sectional, quasi-experimental study was conducted from January-December 2019 at the Virtual University of Pakistan (Rawalpindi campus). The…
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Artikel Jurnal
Pioneering 3D-printed dental crowns for adult patients: a pilot quasi-experimental study in Karachi, Pakistan
Objective: To compare patient-reported clinical outcomes between patients receiving three-dimensional-printed dental crowns versus conventional ones. Method: The pilot, quasi-experimental, single-blind study was conducted at Karachi Medical and Dental College, Karachi, from April to November 2024…
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Artikel Jurnal
Significance of CHEK2 expression in pathogenesis of breast cancer
Objective: To compare the histo-morphological features and CHEK2 expression in breast cancer versus benign breast disease. Methods: This cross-sectional study was conducted at the Department of Anatomy, Basic Medical Sciences Institute, in cooperation with Department of Surgical Units Jinnah…
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Artikel Jurnal
Relationship between anxiety, depression, stress and physical inactivity among university students of Quetta
Objective: To find the frequency of depression, anxiety and stress among university students, and to ascertain the condition’s association with physical inactivity. Method: The cross-sectional, analytical study was conducted from November 2023 to May 2024 at the Quetta Institute of Medical…
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Artikel Jurnal
Determination and comparison of urinary albumin creatinine ratio, neutrophil gelatinase associated Lipocalin and Cyclophilin A in relation to type 2 diabetes duration
Objectives: To determine and compare the levels of Urinary Albumin Creatinine Ratio, Neutrophil Gelatinase Associated Lipocalin and Cyclophilin A among groups based on duration of Type 2 diabetes. Methodology: This is an observational descriptive analytical study. The study was conduction in…
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Artikel Jurnal
Association of congenital abnormalities with maternal risk factors; an ultrasound based case-control study
Objective: To determine the association between foetal congenital abnormalities and maternal risk factors, including family history and consanguinity. Method: The case-control study was conducted from December 2022 to May 2023 at the Radiology Department of Jinnah Postgraduate Medical Center…
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Artikel Jurnal
Dynamics of immune reconstitution in post-allogeneic hematopoietic stem cell transplant patients and effect of potential factors from Pakistani cohort
Objective: To determine the dynamics of immune reconstitution by measuring lymphocyte subsets at periodic intervals after allogenic hematopoietic stem cell transplant, and to assess the impact of potential factors influencing immune reconstitution. Method: The retrospective was conducted at the…
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Artikel Jurnal
Alterations in the levels of cytokines associated with Th17 cells in the plasma of Guillain-Barre syndrome patients
Objective: To compare the cytokines associated with T helper 17 cells between Guillain-Barre syndrome patients and healthy controls. Method: The cross-sectional, comparative study was conducted from March 2024 to February 2025 at the Department of Immunology, University of Health Sciences, Lahore…
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Artikel Jurnal
Long-term survival with congenital Bartter syndrome: A case report
Bartter syndrome is a rare congenital salt-wasting renal tubular disorder, caused by defective salt reabsorption in the thick ascending limb of the loop of Henle. It is characterized by hypokalaemia, hyponatraemia, hypochloraemia, metabolic alkalosis, hyper-reninaemia, and hyperaldosteronism. A 26…
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Artikel Jurnal
Osteoporosis screening by measuring calcaneus bone mineral density through quantitative ultrasonography in healthcare workers
Objectives: To evaluate the frequency of low bone mineral density among healthcare workers, identify gender and age-related trends, and assess the feasibility of implementing routine screening programmes for early detection and prevention of bone health deterioration. Method: The analytical…
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Artikel Jurnal
A comprehensive assessment of cervical cancer risk factors, screening modalities, and cytological outcomes
Objective: To assess risk factors, awareness, screening practices and cytological outcomes related to cervical cancer. Method: The descriptive, cross-sectional study was conducted from January to December 2020 at tertiary care hospitals in Lahore, Pakistan, after approval from the ethics review…
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Artikel Jurnal
Determination of changes in the nutrition and physical activity status of academicians during the pandemic period
Objective: To assess the changes in nutrition habits, physical activity levels, sedentary behaviours, sleep patterns and quality of academicians before and during the coronavirus disease-2019 pandemic. Method: The descriptive, cross-sectional study was conducted from January to September 2022 after…
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