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Acta Medica Indonesiana
Scopus
ISSN 0125-9326 · Interna Publishing · 1.665 artikel di indeks
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Artikel Jurnal
The Relationship Between Serum Interleukin-31 Levels and Chronic Kidney Disease-Associated Pruritus in Patients Undergoing Hemodialysis
Background: Chronic kidney disease-associated pruritus (CKD-aP) has been linked to immune dysregulation, including elevated interleukin-31 (IL-31) levels. However, the limited research on serum IL-31 levels in patients with CKD-aP has yielded inconsistent findings due to heterogeneous patient…
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Artikel Jurnal
Thyroid Dysfunction and Its Association with Glycemic Control in Patients with Type 2 Diabetes Mellitus (T2DM): A Systematic Review and Meta-Analysis
Background: Diabetes mellitus (DM) is characterized by metabolic anomalies, such as hyperglycemia, resulting from pancreatic β-cell dysfunction. In this context, thyroid dysfunction is the second most prevalent endocrine disorder after DM, and the interaction with glycemic control in type 2…
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TIMI Score Modification for Predicting 30-Day Mortality Following Primary Percutaneous Coronary Intervention among STEMI Patients at Cipto Mangunkusumo National Hospital
Background: This study to validate the TIMI (Thrombolysis in Myocardial Infarction) core and also assess the validity of a modified TIMI score that includes three additional variables from primary percutaneous coronary intervention (PPCI) findings: left ventricular ejection fraction based on…
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Artikel Jurnal
Plasma Galectin-3 as a Predictor of Cardiac Dysfunction in Patients Undergoing Doxorubicin Chemotherapy: A Prospective Cohort Study
Background: Doxorubicin is widely used in chemotherapy in oncology. However, it is associated with dose-dependent cardiotoxicity. Thus, early detection of cardiac dysfunction is crucial to preventing heart failure. This study aimed to evaluate plasma Galectin-3 levels, a biomarker of fibrosis and…
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Artikel Jurnal
Diagnostic Performance of Non-Invasive Tests in Assessing Liver Fibrosis Among Type 2 Diabetes Mellitus
Background: Noninvasive tools for assessing liver fibrosis are essential, especially in patients with Type 2 Diabetes Mellitus (T2DM) who are at high risk of developing metabolic dysfunction-associated fatty liver disease (MAFLD). This study aimed to evaluate the correlation between the diagnostic…
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Artikel Jurnal
Cost-Effectiveness Analysis of Multidisciplinary Care in Chronic Heart Failure: Insights from an Indonesian Tertiary Hospital
Background: Chronic heart failure (CHF) is the leading cause of morbidity and healthcare expenditure in Indonesia, largely due to recurrent hospitalizations. Multidisciplinary Programs (MDSs) have been introduced to provide clinical and economic advantages by reducing hospitalizations. This study…
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Artikel Jurnal
Cirrhotic Cardiomyopathy: Proportion and Correlation with Liver Fibrosis Severity
Background: Cirrhotic cardiomyopathy is characterized by an impaired systolic response to stress, diastolic dysfunction, and electrophysiological abnormalities, without underlying structural heart disease. Left ventricular diastolic dysfunction (LVDD) is the most common manifestation found in…
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Artikel Jurnal
Novel Prognostic Model to Predict In-Hospital Mortality in Patients with Liver Cirrhosis
Background: Liver cirrhosis remains a major global health concern associated with high in-hospital mortality, especially in Southeast Asia. Existing prognostic scores, such as Child-Pugh and albumin-bilirubin scores, exhibit variable accuracy, necessitating simpler and more practical tools. This…
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Artikel Jurnal
Acute Respiratory Distress Syndrome and Corticosteroids: Reconciling Conflicting Evidence
Acute respiratory distress syndrome (ARDS) is a life-threatening form of acute inflammatory lung injury in which loss of alveolar-capillary membrane integrity produces protein-rich pulmonary edema, refractory hypoxemia, and reduced lung compliance, typically within 6–72 hours of a precipitating…
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Artikel Jurnal
Uncorrected Tetralogy of Fallot Complicated by Brain Abscess and Postoperative Intracranial Haemorrhage: A Case Report
Cerebral abscess is a rare but potentially fatal complication of cyanotic congenital heart disease, in which chronic hypoxia, polycythaemia and right-to-left shunting allow bacteraemia to bypass pulmonary filtration. A woman in her 20s with uncorrected tetralogy of Fallot presented with severe…
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Artikel Jurnal
Progression of Secondary to Tertiary Hyperparathyroidism with a Coexisting Parathyroid Adenoma in Stage 3b Chronic Kidney Disease: A Case Report
Tertiary hyperparathyroidism arises when prolonged secondary hyperparathyroidism progresses to autonomous parathyroid hormone secretion with persistent hypercalcemia, most often in chronic kidney disease. Diffuse or nodular multiglandular hyperplasia is the expected pathology; a discrete…
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Metabolic Imprinting and Intergenerational Cardiometabolic Risk in Human Populations: Implications for Preconception and Maternal Health
The global rise in obesity and type 2 diabetes has been too rapid to be explained by genetic change alone, which points to developmental and environmental contributions to cardiometabolic risk. Metabolic conditions during sensitive windows, particularly preconception, pregnancy, and early postnatal…
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Artikel Jurnal
Airway Stenting for Benign and Malignant Central Airway Obstruction: A Case Series
Central airway obstruction (CAO) is a life-threatening condition caused by malignant or benign processes involving the trachea and main bronchi. Bronchoscopic airway stenting is an established intervention to restore airway patency, relieve symptoms, and stabilize patients, particularly in urgent…
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Multiple Cavitary Lung Lesions in ANCA-Negative Small Vessel Vasculitis: A Case Report
Multiple cavitary lung lesions present a diagnostic challenge, with a broad differential diagnosis, including infectious, malignant, and autoimmune etiologies. ANCA-associated vasculitis (AAV), particularly in its seronegative form, is a rare yet important cause that is frequently overlooked, as…
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Artikel Jurnal
Scalp and Tongue Necrosis as Rare Manifestations of Giant Cell Arteritis Complicated with a Preauricular Abscess
Giant cell arteritis (GCA) is a systemic vasculitis that involves cranial arteries, the aorta, and its proximal branches, characterized by granulomatous infiltration of the arterial walls. GCA predominantly occurs in older adults, typically those over the age of 50. The etiology of GCA-associated…
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Artikel Jurnal
Geriatric Assessment-Guided Care for Older Adults with Cancer: A Clinical Practice Review
Cancer is a growing global health burden among older adults, with incidence rising most rapidly in low- and middle-income countries. Chronological age alone poorly reflects physiological reserve, comorbidity, frailty, and functional status, which together determine how well an older patient…
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Artikel Jurnal
From Biomarkers to Better Outcomes: Precision Medicine in Modern Internal Medicine
Internal medicine has traditionally focused on population-based approaches, utilizing diagnostic algorithms and treatment thresholds designed for the "average" patient. While beneficial, this one-size-fits-all model often leads to treatment failures. Precision medicine addresses this limitation by…
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Artikel Jurnal
Risk Factors for Multi-Drug Resistance (MDR) Infections in COVID-19 Patients with Secondary Bacterial Infections
Background: The COVID-19 pandemic has significantly affected global health, contributing to an increase in secondary bacterial infections caused by multidrug-resistant (MDR) pathogens, thereby increasing morbidity and mortality. This study aims to evaluate the risk factors of MDR bacterial…
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Artikel Jurnal
Socio-Demographic Characteristics, Income, and Lifestyle of Internists Across Indonesia: A National Cross-Sectional Survey
Background: Internal medicine specialists have always been one of the pillars that support the health of Indonesian people. Currently, there is no available survey regarding the socio-demography, lifestyle, and income of any medical specialist in Indonesia. This study aims to report this gap in…
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Artikel Jurnal
Successful Conservative Management of Right Ventricular Perforation Caused by Temporary Pacemaker Placement during Complex Percutaneous Coronary Intervention: A Case Report
Cardiac tamponade is a critical condition that can result from complications during invasive cardiac procedures. This case report describes a 67-year-old male who developed right ventricular perforation leading to cardiac tamponade following elective complex percutaneous coronary intervention with…
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