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Majalah Kedokteran Bandung
ISSN 0126-074X · Universitas Padjajaran · 687 artikel di indeks
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Artikel Jurnal
Effect of SH-MSC on IL-10 and STAT3 Gene Expression in Infected Wounds
Superficial wounds infected with Staphylococcus aureus trigger inflammatory responses and oxidative stress that impair wound healing. The secretome from hypoxia-conditioned mesenchymal stem cells (SH-MSC) has been shown to modulate inflammation by upregulating anti-inflammatory mediators, including…
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Artikel Jurnal
Tuberculosis Risk Factors in Children Aged 0–5 Years in an Indonesian Hospital
Tuberculosis (TB) is an infectious disease that poses a substantial public health challenge in developing countries, including Indonesia. Children under five years of age show increased susceptibility to the infection due to incompletely developed immune systems. Therefore, this study aimed to…
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Artikel Jurnal
Comparison of Short-Term Memory Levels of Stunted and Non-Stunted Children Aged 2–5 Years
Stunting remains a significant public health issue in developing countries, including Indonesia as it can adversely affect children's growth and development, particularly impairing the maturation of memory functions that may subsequently lead to diminished cognitive abilities. While the effects of…
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Artikel Jurnal
Modulatory Effects of Clitoria ternatea Extract on TNF-α Protein and Gys Gene Expression in Diabetic–Dyslipidemic Rats
Diabetes mellitus (DM) is a metabolic disorder characterized by chronic hyperglycemia resulting from impaired insulin secretion or insulin action. Dyslipidemia is a common complication of DM and is associated with an increased risk of cardiovascular disease. Although pharmacological therapies are…
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Artikel Jurnal
VEGF and NLR as Diagnostic Biomarkers in Malignant, Non-Malignant, and Tuberculosis Pleural Effusion Patients
Differentiating malignant from non-malignant pleural effusions, as well as distinguishing malignancy from tuberculosis, remains challenging and carries significant diagnostic and therapeutic implications. This study aimed to analyze vascular endothelial growth factor (VEGF) level and the…
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Artikel Jurnal
Characteristics and Surgical Outcomes of Pediatric Hypospadias Patients
Hypospadias is a prevalent congenital abnormality in boys, with its exact causes being multifactorial, involving genetic, endocrine, and environmental factors. This study aimed to investigate the characteristics of pediatric hypospadias patients treated at Dr. Hasan Sadikin General Hospital…
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Artikel Jurnal
Relationship between Septum Deviation Type and Radiologic Extent of Middle Ear and Mastoid Infection in CSOM
Chronic suppurative otitis media (CSOM) is a multifactorial inflammatory disease of the middle ear that may be influenced by chronic upper airway pathology, including nasal septum deviation, which can contribute to impaired ventilation of the Eustachian tube and persistence of infection. Several…
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Artikel Jurnal
Laparoscopic Surgery for Liver Abscess and Cholecystitis Caused by Ascariasis
Intrahepatic and gallbladder ascariasis complicated by liver abscess is an exceptionally rare clinical condition that presents significant diagnostic and therapeutic challenges. The migration of Ascaris lumbricoides into the biliary system is uncommon due to the narrow and tortuous anatomy of the…
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Artikel Jurnal
Impact of CYP3A4 and CYP3A5 Genetic Variants on Tacrolimus Dosing and Therapeutic Outcomes in Kidney Transplant Recipients
Tacrolimus is the cornerstone of immunosuppressive therapy in kidney transplantation; however, its narrow therapeutic index and variable metabolism make dose optimization difficult. Genetic variations in the CYP3A4 and CYP3A5 genes significantly influence tacrolimus metabolism yet limited data are…
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Artikel Jurnal
Development of the Diabetic Health Impact Indicator (DHII) as Composite Biomarker Based Score for Diabetes Health Assessment
Diabetes mellitus is a global significant health concern that affects various body systems. Current assessment tools mostly rely on individual biomarkers, which do not fully capture the overall health burden of the disease. Therefore, a comprehensive and understandable measure is needed to evaluate…
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Artikel Jurnal
Whole-Exome Sequencing Reveals SHANK3 and CHD8 Variants in Autism Spectrum Disorder
Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder associated with synaptic dysfunction and chromatin remodeling abnormalities. Among the genes implicated in ASD, SHANK3 and CHD8 play essential roles in synaptic organization and neurodevelopmental regulation. This study aimed…
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Artikel Jurnal
Preliminary Screening of Conjunctivitis-Associated Beta Hemolytic Strains of Staphylococcus aureus and Their Resistance Against Different Antibacterial Agents
Conjunctivitis is one of the most common ocular infections encountered in clinical and hospital settings, particularly among children under seven years of age. This study aimed to evaluate the antimicrobial susceptibility of ophthalmic isolates of Staphylococcus aureus to different antibacterial…
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Artikel Jurnal
Case of Gonorrheal Urethritis and Post-Traumatic Stress Disorder Due to Sexual Abuse in a Boy
Sexual violence against children and the occurence of sexually transmitted infections (STIs), particularly gonorrheal urethritis, are rare in the pediatric population. This case report describes an 8-year-old boy who acquired a sexually transmitted infection uncommon for his age group, suggesting…
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Artikel Jurnal
LRINEC Scoring Accuracy and Its Association with Clinical Outcomes in Necrotizing Fasciitis Patients
Necrotizing Fasciitis (NF) is a soft tissue infection characterized by rapidly progressive necrosis of the fascia and is associated with high morbidity and mortality worldwide. It has atypical clinical symptoms during the early course of the disease, making timely diagnosis challenging. Early and…
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Artikel Jurnal
Physical and Mental Burden of Ocular Surface Squamous Neoplasia on Health-Related Quality of Life
Patients diagnosed with ocular surface squamous neoplasia (OSSN) often experience a significant decline in health-related quality of life (HRQoL) due to its potential for visual impairment. This study aimed to investigate the association between OSSN and HRQoL by considering various determinants. A…
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Artikel Jurnal
Correlation of Age, PSA Value, Gleason Score, and Staging with Metastasis in Prostate Cancer
Prostate cancer is the fifth most common cancer among men in Indonesia and carries a substantial risk of metastasis. However, data on prognostic factors such as age, prostate-specific antigen (PSA) value, Gleason score, and local stage among Indonesian patients are still limited. This retrospective…
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Artikel Jurnal
Patterns of Pulmonary Function in Patients Undergoing Spirometry at a Tertiary Referral Hospital in West Java, Indonesia
Spirometry is a fundamental tool for assessing pulmonary function, as it provides critical insights into respiratory health. This study aimed to explore pulmonary function abnormalities among patients undergoing spirometry at Dr. Hasan Sadikin General Hospital, Bandung, Indonesia. Conducted in May…
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Artikel Jurnal
Types of Social Participation among the Elderly in Bandung City, Indonesia
Elderly individuals are at increased risk of experiencing various health problems associated with isolation and loneliness. Social participation with family, friends, neighbors, and engagement in community activities has been proven to reduce these risks. This study aimed to identify the types of…
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Artikel Jurnal
Correlation Between Pre-Transplant Anemia and Mortality After Kidney Transplantation in Diabetic and Non-Diabetic Patients
Anemia is an established risk factor for mortality and graft failure among kidney transplant recipients, particularly those with diabetes mellitus; however, the combined effects of these conditions remains poorly understood. Regular anemia evaluation is important for patients with End-Stage Kidney…
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Artikel Jurnal
ESBL-Producing Enterobacteriaceae Isolated from Hospital and Community Health Center Wastewater in Pekanbaru, Indonesia
Wastewater originating from medical facilities, particularly hospitals, serves as an important reservoir for Extended-Spectrum Beta-Lactamase (ESBL)-producing bacteria. This study assessed ESBL-producing strains of Escherichia coli and Klebsiella pneumonia in the inlet and outlet of wastewater…