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Ecotoxicology and Environmental Safety
Scopus
ISSN 0147-6513 · Elsevier · 9.056 artikel di indeks
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Artikel Jurnal
Environmental adaptation and functional diversity of calcin peptides from the venom of East Asian scorpions
Toxins as naturally occurring hazardous substances, have evolved as a defense mechanism in organisms for survival. The expression of toxins is profoundly influenced by environmental factors, and the investigation of their correlation holds significant implications for understanding toxin-induced…
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EGFR–Annexin A2 signaling–mediated tauopathy in amyloid-β and aluminum chloride–induced Alzheimer’s disease and its modulation by the HDAC inhibitor butyrate
Alzheimer’s disease (AD) is typified by amyloid-β (Aβ) accumulation and tauopathy, culminating in synaptic destabilization, dendritic atrophy, and widespread neurodegeneration. Epidermal growth factor receptor (EGFR), prominently expressed during neurodevelopment, is largely quiescent in adulthood…
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Long-term exposure to silica nanoparticles induces DNA damage by activating ferritinophagy in the lungs
Amorphous silica nanoparticles (SiNPs) have been extensively produced and applied; therefore, their adverse health effects after long-term exposure should be investigated thoroughly. This study demonstrated that long-term exposure to SiNPs led to persistent DNA damage in the lungs of rats. After…
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Alleviation of microplastic stress on Astragalus mongholicus by selenium-enriched microbial fertilizer
The impact of microplastic pollution on the ecological environment can no longer be ignored, especially the absorption process of microplastics by plants, which is becoming an important link in pollution transmission. At present, the governance of microplastic pollution has been gradually carried…
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Pathophysiological and behavioral consequences of dichlorvos-induced oxidative stress in rodent models: A systematic review of mechanisms and protective strategies
DDVP, a widely used organophosphate insecticide, exerts toxicity primarily through acetylcholinesterase inhibition and redox imbalance, culminating in multi-organ injury. This systematic review compiles findings from rodent studies to outline the toxicodynamic profile of DDVP, emphasizing oxidative…
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Residential greenness mitigates the adverse effects of ambient ozone exposure on sperm quality: A nationwide study in China
Epidemiological studies have linked ambient ozone (O₃) and residential greenness to semen quality, but their interaction has rarely been explored. We conducted a nationwide cross-sectional analysis of 26,997 semen donors from 33 Chinese provinces (from 2019 to 2022), with retrospective…
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Iprodione impairs reproductive health of Chinese honeybee (Apis cerana cerana) drones via morphological alterations, sperm dysfunction, ATPase inhibition, and colony-level compensation mechanisms
Iprodione is a widely used fungicide for preventing various fungal diseases in numerous crops. Its residues in the environment pose potential risks to pollinating insects and may also cause reproductive toxicity in male animals. However, its impact on the reproductive health of drones of the…
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Exposure to 77PD quinone inhibits longevity and healthspan via affecting mitochondrial signals in Caenorhabditis elegans
The 77PD quinone (77PDQ), a member of PPDQs family, can be frequently detected in environment and bioavailable to organisms. In nematodes, toxicity of 77PDQ on longevity and healthspan and underlying mechanism were determined. Exposure to 0.1–10 μg/L 77PDQ reduced lifespan and inhibited healthspan…
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1,3,6,8-Tetrabromocarbazole induces neurodegenerative damage in mice: Mechanistic insights from combined transcriptomic and metabolomic profiling
1,3,6,8-Tetrabromocarbazole (1368-BCZ), an emerging dioxin-like persistent organic pollutant, can enter the body through multiple routes including dietary intake, inhalation, and dermal contact. Growing concerns have been raised about its potential toxicity, particularly regarding its poorly…
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Hexavalent chromium inhalation exposure induces metabolic reprogramming underlying lung injury and partial endogenous repair in mice
Hexavalent chromium [Cr(VI)] is a pervasive toxicant in occupational and environmental settings, posing significant respiratory risks, yet the metabolic mechanisms underpinning its pulmonary toxicity and repair remain unclear. In this study, C57BL/6 J mice underwent 28 days of whole‑body inhalation…
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Association between environmental exposure, gut microbiome and risk of gestational diabetes mellitus in Guangzhou, China
Gestational diabetes mellitus (GDM) is a prevalent pregnancy complication. Both environmental changes and gut dysbiosis have been associated with increased risk of GDM. While environmental exposures may influence gut microbiome, the exact mechanisms linking these factors to GDM risk remain poorly…
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Methyl triclosan alters amino acid and glycerophospholipid metabolism in human ovarian granulosa cells
Methyl triclosan (MTCS) is the principal metabolic product of the broad-spectrum antimicrobial compound triclosan (TCS) and is more toxic to aquatic life. However, knowledge about the toxicity of MTCS to humans and its effect on fertility remains limited. In this investigation, non-targeted…
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Developmental exposure to polystyrene nanoplastics induces persistent neurobehavioral changes and alters later-life susceptibility to hexabromocyclododecane in zebrafish
Micro- and nanoplastic pollution poses a global threat due to environmental accumulation, poor reversibility, and adverse effects on humans and wildlife. Nanoplastics can cross the blood-brain barrier (BBB) and induce neurotoxicity, yet studies investigating the developmental effects of nanoplastic…
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γ-Polyglutamic acid alleviates chromium toxicity in tobacco plants: physiological regulation and microbial mechanismMendeley Data
Chronic chromium (Cr) contamination in agricultural soils causes pronounced physiological perturbations in Nicotiana tabacum L. cv. Honghuadajinyuan, urging eco-friendly remediation strategies. Notably, the multifunctional biopolymer γ-polyglutamic acid (γ-PGA) holds great promise for heavy metal…
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Triphenyl phosphate accelerates collagen-rich ECM remodeling and proliferation in gastric cancer via partially TGFβ/NOTCH-dependent transcription Programs
Organophosphate esters are increasingly used as replacements for legacy halogenated flame retardants, yet their tumor-promoting potential remains poorly defined. Here, we identify triphenyl phosphate (TPP) as a potent environmental driver of extracellular-matrix (ECM) remodeling and growth in…
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Minimal oil exposure causes sublethal damage in early larval stages of a key prey species, lesser sandeel (Ammodytes marinus)
The lesser sandeel (Ammodytes marinus) is a vital forage species in the North Sea, supporting numerous seabird, fish, and marine mammal populations. Its life cycle is characterized by benthic dwelling during juvenile and adult stages and a pelagic larval stage, which makes it especially sensitive…
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Association between prenatal exposure to polycyclic aromatic hydrocarbons and neonatal birth outcomes: Cross-sectional study
This study sought to characterize the concentrations of urinary polycyclic aromatic hydrocarbon (PAH) metabolites in pregnant women across gestational stages and to explore their associations with neonatal birth outcomes. A total of 3689 pregnant women aged 20–45 years were recruited, among whom…
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Spatiotemporal distribution, sources, and ecological risk of steroids in a large shallow lake and its inflows in central China
Steroids in the aquatic environment, including extremely important natural hormones and numerous synthetic hormones, have garnered significant attention due to their endocrine disrupting effects. This study conducted a comprehensive investigation of steroid pollutants in Lake Chao and its inflows…
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1,6-Dihydroxynaphthalene as a potential environmental obesogen induces lipid accumulation and liver developmental defects in zebrafish
1,6-Dihydroxynaphthalene (1,6-DHN), a key dye intermediate and metabolite of polycyclic aromatic hydrocarbons, may pose environmental endocrine-disrupting risks. However, its toxicological effects remain poorly understood. Using zebrafish as a model, this study systematically examined the impact of…
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Efficient and effective immobilization of thallium and organic dyes from wastewater by iron fabricated hydrochar derived from microalgae biomass
Abstracts: Co-pollution of toxic thallium (Tl) and dyes (crystal violet, CV) is common in industrial wastewater, and the coexistence of both significantly increases environmental risk. Meanwhile, large quantities of microalgae biomass generated from algal blooms are typically discarded. In this…
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