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Acta Pharmacologica Sinica
ISSN 0253-9756 · Springer Nature · 12 articles in the index
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Mitochondrial-derived damage-associated molecular patterns amplify neuroinflammation in neurodegenerative diseases
Abstract Both mitochondrial dysfunction and neuroinflammation are implicated in neurodegeneration and neurodegenerative diseases. Accumulating evidence shows multiple links between mitochondrial dysfunction and neuroinflammation. Mitochondrial-derived damage-associated molecular patterns (DAMPs)…
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Natural products: potential treatments for cisplatin-induced nephrotoxicity
Cisplatin is a clinically advanced and highly effective anticancer drug used in the treatment of a wide variety of malignancies, such as head and neck, lung, testis, ovary, breast cancer, etc. However, it has only a limited use in clinical practice due to its severe adverse effects, particularly…
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Artesunate synergizes with sorafenib to induce ferroptosis in hepatocellular carcinoma
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Anti-SARS-CoV-2 activities in vitro of Shuanghuanglian preparations and bioactive ingredients
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Growth factors-based therapeutic strategies and their underlying signaling mechanisms for peripheral nerve regeneration
Peripheral nerve injury (PNI), one of the most common concerns following trauma, can result in a significant loss of sensory or motor function. Restoration of the injured nerves requires a complex cellular and molecular response to rebuild the functional axons so that they can accurately connect…