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Journal of Pharmacy & Pharmacognosy Research
Scopus
ISSN 0719-4250 · GarVal Editorial Ltda. · 828 artikel di indeks
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Artikel Jurnal Teks lengkap
Determinants of adherence to antihypertensive medication among outpatients in a mountainous province of Vietnam: A cross-sectional study
Context: Adherence to antihypertensive medication is essential for blood pressure control. However, adherence patterns in mountainous areas of Vietnam, where socioeconomic and access barriers may differ, remain insufficiently described. Aims: To evaluate adherence to antihypertensive medication and…
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Artikel Jurnal Teks lengkap
Effectiveness of vaccine strategies in modulating immune responses and reducing atherosclerotic lesions in preclinical animal models: A systematic review and meta-analysis
Context: Atherosclerosis is driven by lipid accumulation and chronic immune-mediated inflammation, and immunization strategies have been proposed to modulate pathogenic immune pathways in vivo. Aims: To evaluate the effectiveness of vaccine-based interventions in inducing immune responses and…
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Artikel Jurnal Teks lengkap
Protective effects of Zanthoxylum acanthopodium DC in a DMBA-induced rat model: Renal, inflammatory, and histopathological evaluation
Context: Renal injury associated with carcinogen exposure is often mediated by systemic oxidative stress and inflammation. Zanthoxylum acanthopodium is a medicinal plant rich in bioactive compounds with potential protective effects. Aims: To evaluate the protective effects of Z. acanthopodium…
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Artikel Jurnal Teks lengkap
5-O-Methylgenistein of Phaleria macrocarpa (Scheff.) Boerl. revealed as a potential therapeutic compound for endometriosis
Context: Endometriosis is a chronic estrogen-dependent inflammatory disorder associated with pelvic pain and infertility. Flavonoids from Phaleria macrocarpa have been reported to exhibit anti-inflammatory activity; however, their molecular mechanisms relevant to endometriosis remain insufficiently…
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Artikel Jurnal Teks lengkap
Dietary supplement marketing: The crucial role of psychological factors in customer satisfaction
Context: Dietary supplements are increasingly used to maintain health and prevent illness and are often perceived as non-medicinal products that do not require a prescription or consultation with healthcare professionals. Aims: To examine the impact of psychological factors (attitudes, beliefs, and…
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Artikel Jurnal Teks lengkap
Neuroprotective effects of nanoformulated Paraboea leuserensis B.L.Burtt on memory loss and depression in traumatic brain injury–induced rats: Behavioral and molecular insights
Context: Traumatic brain injury (TBI) is a major neurological disorder leading to memory loss and depression due to neuroinflammation and neuronal damage. Aims: To evaluate the neuroprotective effects of nanoformulated Paraboea leuserensis (PL) on behavioral and molecular alterations in TBI-induced…
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Artikel Jurnal Teks lengkap
Neuroprotective nanotherapy of Paraboea leuserensis in traumatic brain injury: Modulation of oxidative stress, inflammation, and apoptosis
Context: Traumatic brain injury (TBI) is a major cause of disability and mortality worldwide. In addition to the primary insult, secondary mechanisms such as oxidative stress, neuroinflammation, and neuronal apoptosis worsen neurological outcomes. Existing treatments like corticosteroids offer…
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Artikel Jurnal Teks lengkap
Antimalarial activity and toxicity of Garcinia mangostana L. pericarp extracts and major xanthones: A systematic review of in vitro and in vivo studies
Context: Malaria morbidity remains high, and resistance to antimalarial drugs and diagnostics continues to expand. Aims: To systematically evaluate the in vitro/in vivo antimalarial efficacy and toxicity of Garcinia mangostana L. pericarp extracts (MP)/fractions and major xanthones. Methods: A…
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Artikel Jurnal Teks lengkap
Linezolid-related adverse drug reactions in patients with drug-resistant tuberculosis: A retrospective study at a government lung hospital
Context: Drug-resistant tuberculosis (DR-TB) remains a major public health challenge in Indonesia. Treatment outcomes are often compromised by adverse drug reactions (ADRs), particularly those related to prolonged linezolid use. Aims: To compare the incidence and temporal patterns of hematological…
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Artikel Jurnal Teks lengkap
Targeting PCOS-related inflammation with bioactive compounds of Syzygium polyanthum (Wight) Walp. leaves extract: An in silico study
Context: Polycystic ovary syndrome (PCOS) is a prevalent endocrine disorder affecting reproductive-aged women, often associated with chronic inflammation. The search for novel therapeutic agents has led to the exploration of natural compounds with anti-inflammatory properties. Syzygium polyanthum…
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Artikel Jurnal Teks lengkap
Anti-inflammatory activity of phytosomal ethanolic extract of propolis (Tetragonula sp.) in a rat model of carrageenan-induced edema
Context: Propolis from Tetragonula sp. has demonstrated anti-inflammatory effects in studies. However, the limited absorption and permeability of flavonoids reduce their bioavailability and therapeutic use. Phytosomes, as nanocarriers, offer a promising way to improve the bioavailability of…
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Artikel Jurnal Teks lengkap
Neuroprotective effects of Morinda citrifolia L. fruit extract in RCCAO-induced cerebral hypoperfusion in Wistar rats
Context: Cerebral hypoperfusion contributes to neurovascular injury and functional impairment. Morinda citrifolia L. fruits contain bioactive constituents associated with neuroprotective activity in several preclinical models. Aims: To evaluate the neuroprotective effects of an ethanolic extract of…
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Artikel Jurnal Teks lengkap
Salacca zalacca peel modulates uricemia and IL-6 in rats
Context: Hyperuricemia promotes oxidative stress and inflammation. Ethanolic salak (Salacca zalacca) peel extract (ESP) contains flavonoids with antioxidant potential. Aims: To evaluate the effects of ESP on serum uric acid (UA), interleukin-6 (IL-6), and glutathione peroxidase (GPx) protein levels…
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Artikel Jurnal Teks lengkap
Identifying high-efficiency α-glucosidase inhibitors from Abelmoschus manihot (L.) Medik.: A quadrant-based integration of in vitro potency and in silico analysis
Context: α-Glucosidase represents one of the key treatments for diabetes based on its ability to regulate postprandial blood glucose levels. Aims: To evaluate the α-glucosidase inhibitory potential of Abelmoschus manihot (L.) Medik, an endemic species of Minahasa, Indonesia, which is consumed as a…
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Artikel Jurnal Teks lengkap
Additive effects of clove (Syzygium aromaticum) and rosemary (Rosmarinus officinalis) essential oils on hair regrowth in a rat model: A comparative study with 2% minoxidi
Context: Alopecia affects a large population and current treatments have limited efficacy and tolerability. Essential oils have gained increasing interest as natural, low-risk alternatives. Aims: To evaluate the effects of Syzygium aromaticum and Rosmarinus officinalis oils, alone and in…
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Artikel Jurnal Teks lengkap
Phytochemical composition, anti-inflammatory, antioxidant, antimicrobial, antiplasmodial, antidiabetic and anticancer activities of Sonchus arvensis L
Context: Sonchus arvensis L. is widely used both as a traditional medicine and as a nutritional vegetable for its diverse bioactivities. Despite its widespread use, a comprehensive evaluation of its phytochemical profile and therapeutic potential remains limited. Aims: To conduct a review for…
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Artikel Jurnal Teks lengkap
Network pharmacology and molecular docking approach to identify the mechanisms and molecular targets of Allium ascalonicum L. extract against atherosclerosis
Context: Atherosclerosis remains a leading cause of mortality globally, and current therapeutic strategies are often insufficient. Allium ascalonicum L. (shallot) has demonstrated cardioprotective effects, but its molecular mechanisms remain inadequately defined. Aims: To elucidate the molecular…
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Artikel Jurnal Teks lengkap
Differentially expressed genes analysis for diagnostics and therapy of diarrhea due to pathogenicity and antibiotic resistance genes in children
Context: Pediatric diarrhea is often associated with dysbiosis and pathogenic microorganisms, necessitating further molecular investigation. Differential gene expression (DEG) analysis offers potential insights into biomarkers for the molecular pathogenic mechanisms of diarrhea and antibiotic…
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Artikel Jurnal Teks lengkap
Streptomyces sennicomposti GMY01 extract induces apoptosis and cell cycle arrest in T47D breast cancer cells
Context: Streptomyces spp. produces diverse anticancer secondary metabolites. Strain GMY01, isolated from marine sediment, exhibits cytotoxicity against multiple cancer cell lines. Despite that, the anticancer mechanism, especially in breast cancer cell lines T47D, resulting from the ethyl acetate…
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Artikel Jurnal Teks lengkap
Ethnopharmacology of medicinal plants in Morocco’s Central Plateau: Diversity and knowledge transmission
Context: Medicinal plants have historically been integral to Morocco’s healthcare traditions, supported by a rich flora and intergenerational knowledge transmission. Aims: To identify the diversity and traditional uses of medicinal plants in the Central Plateau, and culturally important species…