15 results
Showing 1–15 · 0.18 seconds · RSS
Canadian Medical Association Journal
Scopus
ISSN 0820-3946 · Canadian Medical Association · 15 articles in the index
-
Journal Article Full text
Diagnosis and management of endometriosis
[For a first-person account of endometriosis, see www.cmaj.ca/lookup/doi/10.1503/cmaj.230215][1] KEY POINTS Endometriosis is a chronic condition defined by the presence of endometrial-like tissue outside of the uterus, which can lead to estrogen-driven inflammation. The extent of disease can be
-
Journal Article Full text
Projected estimates of cancer in Canada in 2022
BACKGROUND: Regular cancer surveillance is crucial for understanding where progress is being made and where more must be done. We sought to provide an overview of the expected burden of cancer in Canada in 2022. METHODS: We obtained data on new cancer incidence from the National Cancer Incidence…
-
Journal Article Full text
Shifts in office and virtual primary care during the early COVID-19 pandemic in Ontario, Canada
BACKGROUND: Globally, primary care changed dramatically as a result of the coronavirus disease 2019 (COVID-19) pandemic. We aimed to understand the degree to which office and virtual primary care changed, and for which patients and physicians, during the initial months of the pandemic in Ontario…
-
Journal Article
Evaluation of the relative virulence of novel SARS-CoV-2 variants: a retrospective cohort study in Ontario, Canada
BACKGROUND: Between February and June 2021, the initial wild-type strains of SARS-CoV-2 were supplanted in Ontario, Canada, by new variants of concern (VOCs), first those with the N501Y mutation (i.e., Alpha/B1.1.17, Beta/B.1.351 and Gamma/P.1 variants) and then the Delta/B.1.617 variant. The…
-
Journal Article Full text
Projected estimates of cancer in Canada in 2020
BACKGROUND: report. METHODS: We obtained incidence data from the National Cancer Incidence Reporting System (1984-1991) and Canadian Cancer Registry (1992-2015). Mortality data (1984-2015) were obtained from the Canadian Vital Statistics - Death Database. All databases are maintained by Statistics…
-
Journal Article Full text
Mathematical modelling of COVID-19 transmission and mitigation strategies in the population of Ontario, Canada
BACKGROUND: Physical-distancing interventions are being used in Canada to slow the spread of severe acute respiratory syndrome coronavirus 2, but it is not clear how effective they will be. We evaluated how different nonpharmaceutical interventions could be used to control the coronavirus disease…
-
Journal Article Full text
Probable congenital SARS-CoV-2 infection in a neonate born to a woman with active SARS-CoV-2 infection
KEY POINTS A 40-year-old woman (gravida 2, para 1) was admitted to a tertiary hospital in Toronto, Ontario. She had familial neutropenia, gestational diabetes and a history of frequent bacterial infections, including 3 episodes (sinusitis, skin infection and bronchitis) during this pregnancy, which
-
Journal Article Full text
Obesity in adults: a clinical practice guideline
KEY POINTS Obesity is a complex chronic disease in which abnormal or excess body fat (adiposity) impairs health, increases the risk of long-term medical complications and reduces lifespan.[1][1] Epidemiologic studies define obesity using the body mass index (BMI; weight/height2), which can stratify
-
Journal Article Full text
Development of the Instrument to assess the Credibility of Effect Modification Analyses (ICEMAN) in randomized controlled trials and meta-analyses
BACKGROUND: Most randomized controlled trials (RCTs) and meta-analyses of RCTs examine effect modification (also called a subgroup effect or interaction), in which the effect of an intervention varies by another variable (e.g., age or disease severity). Assessing the credibility of an apparent…
-
Journal Article Full text
Smartphones, social media use and youth mental health
KEY POINTS In the last decade, increasing mental distress and treatment for mental health conditions among youth in North America has paralleled a steep rise in the use of smartphones and social media by children and adolescents. In Ontario, the proportion of teenagers reporting moderate to serious
-
Journal Article Full text
COVID-19 and people experiencing homelessness: challenges and mitigation strategies
KEY POINTS Infectious disease epidemics and pandemics have a disproportionate impact on people experiencing poverty, marginalization, stigmatization and discrimination.[1][1]–[3][2] Amid the current coronavirus disease 2019 (COVID-19) pandemic, this disparity is particularly relevant for
-
Journal Article Full text
Mitigating the psychological effects of COVID-19 on health care workers
KEY POINTS Although tremendous efforts are being made to investigate the pathophysiology, clinical outcomes and treatment of coronavirus disease 2019 (COVID-19), the psychological effects of this pandemic on health care workers cannot be overlooked. Experience from the 2003 severe acute respiratory
-
Journal Article Full text
Impact of climate and public health interventions on the COVID-19 pandemic: a prospective cohort study
BACKGROUND: It is unclear whether seasonal changes, school closures or other public health interventions will result in a slowdown of the current coronavirus disease 2019 (COVID-19) pandemic. We aimed to determine whether epidemic growth is globally associated with climate or public health…
-
Journal Article Full text
For-profit long-term care homes and the risk of COVID-19 outbreaks and resident deaths
BACKGROUND: Long-term care (LTC) homes have been the epicentre of the coronavirus disease 2019 (COVID-19) pandemic in Canada to date. Previous research shows that for-profit LTC homes deliver inferior care across a variety of outcome and process measures, raising the question of whether for-profit…
-
Journal Article Full text
Safety considerations with chloroquine, hydroxychloroquine and azithromycin in the management of SARS-CoV-2 infection
KEY POINTS Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread rapidly around the globe in recent months. With deaths from its associated disease, coronavirus disease 2019 (COVID-19), projected to reach into the millions and a vaccine unlikely in the near term, the search is on