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Yanke Xuebao
ISSN 1000-4432 · Zhongshan Ophthalmic Center, Sun Yat-sen University · 162 artikel di indeks
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Artikel Jurnal
Microglial modulation of maturation and vascularization in retinal organoids: current advances and future perspectives
Human induced pluripotent stem cell (hiPSC)-derived retinal organoids (ROs) have emerged as robust in vitro platforms for investigating retinal development and disease mechanisms. However, traditional ROs models typically lack essential immune components, specifically microglia, which limits their…
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Artikel Jurnal
Three-dimensional characteristics and their clinical significance of the choroidal vascularity index in wet age-related macular degeneration
Objective: This study aims to utilize swept-source optical coherence tomography angiography (SS-OCTA) technology to investigate the distribution characteristics and clinical significance of the three-dimensional choroidal vascularity index (3D-CVI) in patients with wet age-related macular…
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Artikel Jurnal
Practice in the establishment and management of a rhegmatogenous retinal detachment green channel in an ophthalmic specialty hospital
Fresh rhegmatogenous retinal detachment (RRD) is a common ophthalmic emergency in which surgical timing directly determines visual prognosis. Under conventional diagnostic and treatment models, the interval from diagnosis to surgery averaged 7 to 14 days, substantially limiting functional visual…
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Artikel Jurnal
Health promotion behaviors and their influencing factors among patients with diabetic retinopathy
Objective: To investigate the current status of health promotion behaviors among patients with diabetic retinopathy (DR) and analyze their relationship with sociodemographic characteristics and illness perception, providing an empirical basis for tailored health education and behavioral…
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Artikel Jurnal
Standardized emergency treatment protocol for fresh rhegmatogenous retinal detachments
Rhegmatogenous retinal detachment is a common cause of acute vision loss and requires timely surgical intervention. Photoreceptor damage begins within 12 hours of retinal detachment and typically peaks at 2 to 3 days. Macular involvement without timely surgery often results in severe, irreversible…
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Artikel Jurnal
A study on visual quality of life and mental health status of cataract patients with different economic support conditions
Objective: To explore differences in visual quality of life and mental health among cataract patients with varying economic support statuses (five-guarantee households and non-five-guarantee households) and to identify the influencing factors. Methods: A cross-sectional study was conducted. From…
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Artikel Jurnal
Big data evaluation and analysis on the availability and affordability of negotiated ophthalmic drugs from 2016 to 2023
Objective: To investigate the changes in the accessibility and affordability of ophthalmic drugs under national negotiation before and after its implementation, and to provide a basis for evaluating the implementation effect and optimizing the negotiation policy. Methods: Using descriptive…
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Artikel Jurnal
Awareness, information needs, and influencing factors for eye health management among Guangzhou residents
Objective: To assess the current status of eye health management awareness and service needs among Guangzhou residents and to identify factors influencing their willingness to participate. Methods: A cross-sectional survey was conducted among 499 Guangzhou residents from September 2024 to January…
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Artikel Jurnal
Research advances of circulating tumor DNA in retinoblastoma
Retinoblastoma (RB) is the most common primary intraocular malignancy in children, originating from retinal photoreceptor precursor cells. It is highly malignant and can be life-threatening if not treated promptly. Currently, the diagnosis of RB mainly relies on clinical features, such as fundus…
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Artikel Jurnal
Disease burden of cataract attributable to high BMI and its changing trends globally and in China from 1990 to 2021
Objective: To investigate the disease burden and trends of cataract attributable to high body mass index (BMI) globally and in China from 1990 to 2021, analyze its distribution by age, sex, and socio-demographic index (SDI), and project future trends from 2022 to 2040. The study aim is to provide…
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Artikel Jurnal
Application of corneal visualization scheimpflug technology in ophthalmology
The Corneal Visualization Scheimpflug Technology (Corvis ST) combines ultra-high-speed Scheimpflug imaging with non-contact tonometry, allowing for dynamic monitoring of the corneal deformation and recovery process. It provides a range of key biomechanical parameters, including highest concavity…
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Artikel Jurnal
Global and regional trends in cataract burden attributable to household air pollution, 1990-2021:comparative analysis across China and high-burden regions
Objective: To analyze the sex- and age-specific distribution of cataract attributable to household air pollution (HAP) globally, in China, and in high-burden regions (South Asia, Southeast Asia, Oceania, and sub-Saharan Africa) from 1990 to 2021, and to project trends through 2035. This study aims…
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Artikel Jurnal
Age-related macular degeneration burden and its age-specific patterns across different socio-demographic index regions: an analysis based on the Global Burden of Disease database
Objective: To analyze the disease burden and trends of age-related macular degeneration (AMD) globally and across different Socio-Demographic Index (SDI) regions from 1990 to 2021, using the data from the Global Burden of Disease (GBD) 2021. Methods: Data were sourced from the GBD 2021 database…
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The relationship between serum sexual hormone levels and female tear drainage time
Objective: To investigate the relationship between serum sex hormone levels and tear drainage time. Methods:Female health volunteers from the physical examination center between May 2023 to May 2024 were selected. Using a menopause duration of ≥12 months as the criterion for menopause, they were…
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Artikel Jurnal
Clinical commonly used drug-induced dry eye and its related pathogenesis
Dry eye is a disease caused by abnormal secretion from cells or glands responsible for producing the three layers of tear film on the ocular surface due to various reasons, leading to reduced tear film stability and ocular surface damage. This, in turn, results in ocular discomfort and visual…
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Artikel Jurnal
The application of visual impairment simulation training based on DIKW model in the training of novice ophthalmic nurses
Objective: To investigate the application effects of visual impairment simulation training based on the data-information-knowledge-wisdom (DIKW) model on humanistic professional competence, empathy, professional identity, patient satisfaction, and the incidence of adverse events among newly…
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Artikel Jurnal
Research progress on retinal astrocytes in retinal angiogenesis
Retinal astrocytes, as key elements of the neurovascular unit, fulfill a multitude of roles in preserving retinal homeostasis. These roles include providing structural support, supplying nutrients, facilitating metabolic waste clearance, and regulating immune responses. This review presents a…
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Artikel Jurnal
Progress on ferroptosis and ocular surface diseases
Ferroptosis, a unique form of regulated cell death marked by iron-dependent lipid peroxidation, has attracted considerable attention in recent ophthalmic research due to its cruciall role in the pathogenesis of various ocular disorders. This process entails the build-up of lipid peroxides, which…
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Experiences and in-depth reflection on the clinical skills competition for ophthalmic residents in Guangdong Province
The inaugural Guangdong Province Ophthalmology Resident Clinical Skills Competition was jointly organized by the Ophthalmologists Branch of the Guangdong Medical Association and Zhongshan Ophthalmic Center, Sun Yat-sen University in August 2024. This event drew participants from 30 ophthalmology…
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Artikel Jurnal
Expert consensus on the application of topical anesthetics in ophthalmic surgery
Topical ocular anesthesia is conducted by the instillation of topical anesthetics into the conjunctival sac to temporarily block sensory nerve conduction in the ocular surface area, thereby anesthetizing the area of cornea and conjunctiva. Now, topical anesthesia has become main important…