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Kouqiang yixue
ISSN 1003-9872 · Editorial Office of Stomatology · 389 articles in the index
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Research progress in nanomaterials for the diagnosis and therapy of oral cancer
Oral cancer is one of the most common malignant tumors in the head and neck region, and its early diagnosis and effective treatment remain major clinical challenges. Conventional approaches such as surgery, radiotherapy, and chemotherapy exhibit limited efficacy and are often accompanied by various…
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Analysis of jaw bone CBCT based on motion blur modeling and inverse filtering enhancement
Objective To evaluate the feasibility of inverse filtering for cone-beam computed tomography(CBCT) assessment in dental implantology and to establish a workflow integrating inverse filtering enhancement with CTAn-based bone microstructural analysis, so as to improve the accuracy of peri-implant…
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Clinical study of immediate alveolar ridge reconstruction in immediate implant in the esthetic area
Objective To investigate and evaluate the clinical efficacy of immediate alveolar ridge reconstruction for tissue defects in the maxillary aesthetic zone. Methods Thirty patients undergoing immediate implant placement and restoration of maxillary anterior teeth at the Department of Prosthodontics…
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Construction and analysis of a three-dimensional finite element model of the cranio-maxillary complex and palatal obturator in neonates with unilateral complete cleft lip and palate
Objective To construct a three-dimensional finite element model of the cranio-maxillary complex combined with a palatal obturator in neonates with unilateral complete cleft lip and palate(UCCLP), and to evaluate the effects of different combinations of alveolar cleft closure distance and palatal…
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Research progress of immunotherapy for head and neck squamous cell carcinoma
The treatment paradigm for head and neck squamous cell carcinoma(HNSCC) has undergone fundamental changes since the emergence of immune checkpoint inhibitors(ICIs). This article provides a systematic review of the latest advances in HNSCC immunotherapy. ICIs, represented by PD-1 inhibitors, have…
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Analysis of risk factors for root resorption of adjacent teeth caused by impacted supernumerary teeth in the mandibular premolar region
Objective To investigate the influencing factors of adjacent tooth root resorption caused by impacted supernumerary teeth in the mandibular premolar region. Methods A retrospective study was conducted on 231 patients (with a total of 260 impacted supernumerary teeth). Cone-beam computed tomography…
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Capnocytophaga gingivalis promotes the migration and invasion of oral squamous cell carcinoma cells mediated by the IL-6/JAK2/STAT3 pathway
Objective To investigate the promotion of the migration and invasion of oral squamous cell carcinoma (OSCC) cells by Capnocytophaga gingivalis(C. gingivalis) mediated by the interleukin-6(IL-6)/Janus kinase 2(JAK2)/signal transducer and activator of transcription 3(STAT3) pathway. Methods SCC9…
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Experimental study on enamel remineralization induced by remineralization solutions with different calcium-to-phosphate ratios mediated by P-PAMAM
Objective To investigate the effects of remineralization solutions with different calcium-to-phosphate ratios on the properties of the remineralized layer induced by phosphorylated polyamidoamine (P-PAMAM) dendrimers, to determine appropriate P-PAMAM mass concentrations and calcium-to-phosphate…
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Study on the correlation between the wear characteristics of maxillary first molars and posterior dentition
Objective To explore the correlation between the wear area of the four cusps of maxillary first molars and the height of functional/non-functional cusps of maxillary posterior dentition cusp, cusp inclination, wear area and contact area (including the maxillary first molar), in order to provide a…
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Impact of timing of soft tissue augmentation on clinical prognosis for preventing peri-implantitis
Objective To investigate the effects of soft tissue augmentation procedures performed preoperatively and postoperatively on the health status of peri-implant soft tissues and the extent of bone resorption. Methods A retrospective analysis was conducted on 9 implant patients (totaling 12 implants)…
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Clinical considerations and decision-making in PAOO
The demand for adult orthodontic treatment is increasing, yet patients often face challenges such as prolonged treatment duration and elevated risks of periodontal complications. Periodontal accelerated osteogenic orthodontics(PAOO), which combines corticotomy with bone grafting, leverages the…
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Study on detection of saliva fingerprint spectrum based on surface enhanced Raman scattering technology for screening of periodontitis
Objective To explore the feasibility of using surface enhanced Raman scattering (SERS) to distinguish the saliva of patients with periodontitis from healthy people. Methods A total of 26 healthy volunteers and 26 periodontitis patients were enrolled as study subjects. General demographic data…
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Recent advances in comprehensive treatment of bone healing complications in jaw fractures
Bone healing complications following jaw fractures can markedly impair facial morphology and oral function and are often difficult to manage. This review summarizes the definition and risk factors of bone healing complications in jaw fractures, with a particular focus on comprehensive management…
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Pan-cancer analysis of the oncogenic role of interferon alpha-inducible protein 27 in tumors
Objective To investigate the differential expression of the IFI27 gene across various cancers and evaluate its potential as a prognostic biomarker. Methods A pan-cancer analysis was conducted using data from The Cancer Genome Atlas(TCGA) database, incorporating multiple online tools and R software…
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Causal relationship between sex hormones and oral lichen planus
Objective To investigate the causal relationship between serum sex hormone levels and oral lichen planus (OLP) using Mendelian randomization (MR), with supplementary serological validation. Methods A bidirectional two-sample MR analysis was conducted using publicly available genome-wide association…
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Comparison of direct microscopic examination and antigen detection methods for the diagnosis of oral candidiasis
Objective To compare the detection efficacy of direct microscopic examination and antigen detection in oral candidiasis infection, and provide a basis for clinical selection of rapid detection methods. Methods Oral swabs were collected from patients with suspected oral candidiasis in the Department…
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Bite plates in orthodontics: Therapeutic efficacy and clinical applications
Bite plates are essential auxiliary devices in orthodontic treatment, comprising various types such as fixed bite turbos, removable bite plates, and bite ramps used in clear aligner therapy. By modulating occlusal force distribution and mandibular position, these devices play a critical role in…
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Relationship between apical periodontitis and local marginal alveolar bone loss: A retrospective study
Objective To investigate the association between apical periodontitis(AP) and local marginal alveolar bone loss(ABL) based on cone beam computed tomography(CBCT). Methods This study adopted an intra-subject contralateral paired design. A total of 48 patients with 60 pairs of matched teeth were…
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Clinical study on the anterior approach for superior laryngeal nerve block combined with remimazolam for awake tracheal intubation in patients with hypertension
Objective To evaluate the clinical efficacy and safety of the anterior approach for ultrasound-guided superior laryngeal nerve (SLN) block combined with remimazolam for awake tracheal intubation in patients with hypertension and difficult airways. Methods A total of 60 patients with difficult…
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Analysis of factors influencing changes in residual ridge height and maxillary sinus mucosal thickness in the maxillary molar region of patients with periodontitis
Objective To investigate the factors influencing changes in residual ridge height (RRH) and maxillary sinus mucosal thickness (MT) in the maxillary molar region of patients with periodontitis. Methods A retrospective analysis was conducted on clinical and cone beam computed tomography(CBCT) data…