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Yixue xinzhi zazhi
Scopus
ISSN 1004-5511 · Editorial Office of New Medicine · 713 articles in the index
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Application of digital teaching mode in outpatient general practice professional master training
General practitioners are the backbone of primary health care, responsible for the diagnosis and treatment of common diseases, the rational diversion of medical resources and continuous medical services. The "5+3" model adopted in the training of general practitioners in China has limitations in…
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A case report of vascular stent implantation for the treatment of hepatic venous outflow obstruction after liver transplantation and literature review
Hepatic venous outflow obstruction (HVOO) is a rare but life-threatening complication after liver transplantation. This article reports a 71-year-old male patient who developed localized stenosis of the infrahepatic inferior vena cava after piggyback liver transplantation for primary liver cancer…
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Research progress on the role of microRNA in epithelial-mesenchymal transition of colorectal cancer
Colorectal cancer (CRC) is the third most common cancer globally, with an incidence rate ranked just behind lung cancer and breast cancer in women. Epithelial-mesenchymal transition (EMT) enhances the migratory and invasive abilities of tumor cells but is also closely associated with tumor…
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The research progress of fibroblast growth factor 21 in retinal neovascularization diseases
Retinal neovascularization (RNV) diseases are one of the leading causes of visual impairment and blindness, including diabetic retinopathy, retinopathy of prematurity, retinal vein obstruction, and wet age-related macular degeneration. In recent years, fibroblast growth factor 21 (FGF21), a…
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Meta-integration of qualitative studies on the inner experience and nursing needs of breast cancer patients during radiotherapy and chemotherapy
Objective To systematically synthesize qualitative evidence on the inner experiences and care needs of Chinese breast cancer patients during radiotherapy and chemotherapy.Methods A systematic search was conducted in databases including PubMed, Web of Science, Embase, Cochrane Library, CNKI, VIP…
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Meta-analysis of the incidence and influencing factors of sleep disorders in patients with coronary heart disease
Objective To analyze the prevalence of sleep disorders among patients with coronary heart disease (CHD) and identify their associated influencing factors, thereby providing evidence to improve sleep quality in this patient population.Methods Systematic retrieval of Cochrane Library, PubMed, Web of…
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AURKA promotes Temozolomide resistance in glioma cells by inhibiting ferroptosis through activation of the JAK2/STAT3 pathway
Objective To investigate the impact of Aurora kinase A (AURKA) on Temozolomide (TMZ) resistance in glioma cells and its regulatory role in ferroptosis.Methods The expression profile of AURKA in glioma and its correlation with prognosis were explored using the GEPIA2 database. U87MG/TMZ and…
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SOX9 promotes ovarian cancer progression through activating ferroptosis via SLC7A11/GPX4 pathway
Objective To investigate the role and mechanism of sex-determining region Y-box protein 9 (SOX9) in the progression of ovarian cancer.Methods The ovarian cancer cell lines with stable knockdown of SOX9 were constructed. The effects of SOX9 knockdown on the proliferation, invasion and migration…
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Analysis of burden of type 2 diabetes mellitus and its attributable risk factors in global and China from 1990 to 2021
Objective To assess the changes in the disease burden and risk factors of type 2 diabetes mellitus (T2DM) globally and in China from 1990 to 2021 and predict their future trends.Methods Based on the Global Burden of Disease 2021 database, the age-standardized incidence rate (ASIR), age-standardized…
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The relationship between exercise duration, sleep duration, and depressive symptoms in adults in China: an empirical study based on the CFPS database 2022
Objective To examine the relationship and interaction effects between exercise duration, sleep duration, and depressive symptoms among Chinese adults.Methods Data from the 2022 China Family Panel Studies (CFPS) were used, restricted cubic spline (RCS) and multiple linear regression models were…
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Constructing a depression risk prediction model for elderly people with activities of daily living impairment based on machine learning algorithms
Objective Explore the influencing factors of depression in elderly people with activities of daily living (ADL) disorders, and construct a depression risk prediction model for elderly people with ADL disorders in China based on machine learning (ML) algorithms.Methods Based on the fifth round of…
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Detection value of umbilical artery pulsatility index in growth-restricted fetuses
Objective To investigate the impact and predictive value of bilateral umbilical artery (UA) pulsatility index (PI) abnormalities on perinatal outcomes in fetuses with fetal growth restriction (FGR).Methods FGR fetuses and their mothers who delivered at the Central Hospital of Enshi Tujia and Miao…
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Construction of a predictive model of deep vein thrombosis in elderly patients with hip fractures
Objective To identify risk factors for preoperative lower limb deep vein thrombosis (DVT) in elderly patients with hip fractures and to develop a predictive nomogram model.Methods Elderly patients with hip fractures admitted to the Third Affiliated Hospital of Guangzhou University of Chinese…
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Efficacy and safety of SOX chemotherapy combined with Sintilimab immunotherapy in treatment of patients with advanced gastric cancer
Objective To investigate the efficacy and safety of Sintilimab combined with SOX regimen in the treatment of patients with advanced gastric cancer.Methods The clinical data of patients with advanced gastric cancer in Wuxi Branch, Ruijin Hospital, Shanghai Jiaotong University School of Medicine from…
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Correlation between epidemiological characteristics and meteorological factors in critically ill patients with respiratory failure
Objective To analyze the clinical epidemiological characteristics of critically ill patients with respiratory failure, utilizing spatial epidemiological methods to investigate the relationship between disease onset and seasonal variations, as well as the impact of meteorological factors. Methods A…
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Research on living clinical practice guidelines in diabetes mellitus Ⅰ: a qualitative study of public-oriented web-based knowledge platform and guideline dissemination
Objective To understand the perceptions and needs of target users of the public-facing diabetes knowledge platform, and to provide support and guidance for the construction and optimization of the platform. Methods Using convenience sampling and employing a descriptive qualitative research…
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Voxel-based analysis of tremor-dominant Parkinson's disease: a study on brain magnetic resonance diffusion tensor imaging
Objective To investigate the diagnostic value of diffusion tensor imaging (DTI) technology in tremor-dominant Parkinson's disease (TD-PD).Methods Prospectively included TD-PD patients diagnosed in the Department of Neurology in the Yibin Second People's Hospital from December 2019 to March 2023…
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Ultrasound features of 33 cases of histiocytic necrotizing lymphadenitis in children
Objective To analyze the ultrasonic features of cervical lymph nodes and related involved sites in children with histiocytic necrotizing lymphadenitis (HNL).Methods The clinical data of children with HNL admitted to the First Affiliated Hospital of Henan University of Chinese Medicine between May…
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Research progress on granulosa cell apoptosis in premature ovarian failure
Premature ovarian failure (POF) is a pathological condition characterised by the decline of ovarian function in women under the age of 40. It is closely associated with decreased fertility, elevated risks of osteoporosis and cardiovascular diseases, and has emerged as a significant clinical issue…